Clinical cases in hepatology / / Nora V. Bergasa, editor

• Pubblicazione: London : , : Springer-Verlag, , [2022]; ©2022
• Descrizione fisica: 1 online resource (502 pages)
• Disciplina: 616.362
• Soggetto topico: Liver - Diseases; Liver - Diseases - Treatment
• Persona (resp. second.): BergasaNora V.
• Nota di contenuto: Intro -- Preface -- Acknowledgements -- Contents -- Chapter 1: The Liver -- Hepatic Blood Flow -- Liver Lymphatics -- Liver Histology -- Liver Organization -- Liver Function -- References -- Chapter 2: Approach to the Patient with Liver Disease -- Symptoms of Liver Disease -- Jaundice -- Fatigue -- Pruritus -- Poor Appetite and Weight Loss -- Abdominal Pain -- Alterations in the Senses of Taste and Smell -- Personality Changes and Sleep Disturbances -- Dyspnea -- Bleeding -- Stool Characteristics -- Vision Disturbance -- Bone Pain and Fractures -- Pain -- Hyperpigmentation -- Vascular Ulcers -- Chills and Rigors -- Dark Urine -- Sexual Dysfunction and Disinterest -- Muscle Cramps -- Identification of Risks for Liver Disease -- Recognizing Hepatic Manifestations of Comorbidities -- Past Medical and Surgical History -- Family History -- Review of Systems -- The Physical Examination -- Fetor Hepaticus -- The Skin, Mucous Membranes, and Nails -- Glands and Lymph Nodes -- Cardiovascular System -- Respiratory System -- Abdomen -- Extremities -- Neuropsychiatric Alterations -- Investigation of Liver Disease -- Liver Biopsy -- References -- Chapter 3: Primary Biliary Cholangitis -- Etiology -- Genetics -- Epigenetics -- Epidemiology -- Clinical Manifestations -- Natural History -- Associated Conditions -- Physical Exam -- Laboratory Exams -- Radiographic Studies -- Serology and Immunological Features -- Histology -- Cellular Immunology -- Treatment -- Treatment of Complications of PBC -- Pruritus -- Fatigue -- Sicca Symptoms -- Osteoporosis -- Complications Secondary to Chronic Scratching -- Cholelithiasis -- Xanthomata and Xanthelasmata -- Complications from Liver Disease from PBC -- Portal Hypertension -- Hepatocellular Carcinoma -- Hepatic Synthetic Dysfunction -- References -- Chapter 4: Autoimmune Hepatitis -- Autoimmune Hepatitis -- Etiology. ; Pathogenetics -- Genetics -- Epigenetics -- Clinical Manifestations -- Physical Examination -- Autoantibodies -- Histology -- Diagnostic Scores for AIH -- Overlap Syndromes -- Treatment of Autoimmune Hepatitis -- Hepatocellular Carcinoma -- Autoimmune Hepatitis in Children -- Liver Transplantation -- References -- Chapter 5: Primary Sclerosing Cholangitis -- Sclerosing Cholangitis -- Etiology -- Genetics -- Clinical Manifestations -- Differential Diagnosis -- Physical Examination -- Laboratory Findings -- Diagnosis -- Immunology -- Cellular Pathogenesis -- Dysbiosis -- Histology -- Epidemiology -- Natural History -- Liver Transplantation -- Cholangiocarcinoma -- Treatment -- Therapy of Complications Unique to PSC -- Liver Transplantation -- PSC in Children -- References -- Chapter 6: Chronic Hepatitis C -- Etiology -- Genetics -- Epidemiology -- Natural History -- Clinical Manifestations -- Physical Exam -- Differential Diagnosis -- Histology -- Extrahepatic Manifestations -- Diagnosis -- Treatment -- Treatment of Conditions Associated with Chronic Hepatitis C -- Cryoglobulinemia -- Porphyria Cutanea Tarda -- Nephropathy -- Xerostomia and Xerophthalmia -- Lichen Planus -- Liver Transplantation -- References -- Chapter 7: Chronic Hepatitis B -- Etiology of Chronic Hepatitis B: Hepatitis B Virus -- Genetics -- Epidemiology -- Clinical Manifestations -- Extrahepatic Manifestations -- Characteristics of Chronic Hepatitis B Virus Infection -- Laboratory Findings and Serology -- Differential Diagnosis -- Liver Histology -- Natural History of Chronic Hepatitis B -- Impact of Coinfection with HIV, HCV, and Delta Hepatitis Viri on the Natural History of Chronic Hepatitis B -- Delta Hepatitis -- Treatment of Chronic Hepatitis B -- Indications for Treatment of Hepatitis B -- Drugs for the Treatment of Chronic Hepatitis B -- Treatment of Chronic Delta Hepatitis. ; Liver Transplantation in Patients with Chronic Hepatitis B and Chronic Delta Hepatitis -- Hepatocellular Carcinoma in Chronic Hepatitis B -- References -- Chapter 8: Alcohol Induced Liver Disease -- Etiology -- Genetics -- Epidemiology -- Natural History of Alcoholic Liver Disease -- Clinical Manifestations -- Associated Conditions -- Laboratory and Radiological Exams -- Histology -- Treatment -- Alcohol Withdrawal -- Delirium Tremens -- Treatment of Alcoholic Hepatitis -- References -- Chapter 9: Nonalcoholic Fatty Liver Disease -- Epidemiology -- Etiology -- Genetics -- Clinical Manifestations -- Natural History -- Liver Histology -- Inflammation: Its Potential Role in the Pathogenesis of NAFLD -- NAFLD Associated Diseases -- Lean Nonalcoholic Fatty Liver Disease -- Treatment -- Bariatric Surgery -- References -- Chapter 10: Alpha-1-Antitrypsin Deficiency -- Genetics -- Epidemiology -- Natural History -- Clinical Manifestations -- Laboratory Tests -- Histology -- Hepatocellular Carcinoma -- Associated Conditions -- Treatment -- Liver Transplantation -- References -- Chapter 11: Hemochromatosis -- Iron Homeostasis -- Hepcidin -- Iron Mediated Injury -- Genetics -- Epidemiology -- Natural History -- Clinical Manifestations -- Laboratory Tests -- Histology -- Treatment -- Liver Transplantation -- Treatment of Other Genetic Iron Overload Conditions -- Potential Pharmacological Treatment of Hepcidin-Ferroportin Disease -- References -- Chapter 12: Wilson's Disease -- Etiology -- Copper Homeostasis -- Genetics of Wilson's Disease -- Epigenetics -- Epidemiology -- Natural History -- Clinical Manifestations -- Acute Liver Failure -- Liver Histology -- Laboratory Findings -- Diagnostic Investigations -- Imaging Studies -- Transient Elastography -- Screening in Wilson's Disease -- Treatment -- Hepatocellular Carcinoma -- Liver Transplantation -- References. ; Chapter 13: Tumors of the Liver -- Simple Hepatic Cysts -- Polycystic Liver Disease -- Hydadtic Cysts -- Liver Abscess -- Hepatic Hemangiomata -- Focal Nodular Hyperplasia -- Hepatocellular Adenomata -- Hepatocellular Carcinoma -- Fibrolamellar Carcinoma -- Intrahepatic Cholangiocarcinoma -- Hepatic Angiosarcoma -- Hepatic Epithelioid Hemangioendothelioma -- Hepatic Mucinous Cystic Neoplasm -- References -- Chapter 14: Drug Induced Liver Injury -- Etiology -- Risk Factors for Dili -- Genetics -- Age -- Gender -- Race and Ethnicity -- Alcohol -- Pregnancy -- Comorbidities -- Chronic Liver Disease -- Drug Dependent Risk Factors -- Drug Metabolism -- Lipophilicity -- Drug Interactions -- Mitochondrial Toxicity -- Inhibition of Hepatobiliary Transporters -- Epidemiology -- Approach to a Patient with Suspected Drug-Induced Liver Injury -- Clinical Manifestations -- Laboratory Exams -- Imaging Studies -- Liver Histology -- Natural History -- Associated Conditions -- Treatment -- Prevention of Drug-Induced Liver Injury -- References -- Chapter 15: Complications of Liver Disease -- Pruritus -- Therapies that Aim at the Removal of the Pruritogenic Substances(s) from the Body -- Antibiotics -- Changes in Neurotransmission -- Opiate Antagonists -- Serotonin Antagonists -- Antidepressants -- Potential Regulation of a 24-Hour Rhythm of Scratching Behavior -- Drugs to Treat the Liver Disease -- Fatigue -- Portal Hypertension -- Ascites -- Hepatic Hydrothorax -- Hyponatremia -- Bacterial Infections -- Spontaneous Bacterial Peritonitis -- Renal Insufficiency -- Hepatorenal Syndrome -- Muscle Cramps -- Hepatic Encephalopathy -- Cardiomyopathy -- Hepatopulmonary Syndrome -- Portopulmonary Hypertension -- Fat Malabsorption -- Vitamin Deficiencies -- Gynecomastia -- Cholelithiasis -- Malnutrition -- References -- Index.
• Sommario/riassunto: Comprising chapter-length case studies of patients with varied liver pathologies, this work enriches the knowledge of trainees and practicing clinicians, and includes a wealth of biopsy photographs, epidemiological analysis, and tabulated experimental data.
• Titolo autorizzato: Clinical Cases in Hepatology
• ISBN: 1-4471-4715-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910522960503321
• Lo trovi qui: Univ. Federico II