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Randomized phase II cancer clinical trials / / Sin-Ho Jung



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Autore: Jung Sin-Ho Visualizza persona
Titolo: Randomized phase II cancer clinical trials / / Sin-Ho Jung Visualizza cluster
Pubblicazione: Boca Raton, Fla. : , : Taylor & Francis Group, , 2013
Descrizione fisica: 1 online resource (236 p.)
Disciplina: 616.994060724
Soggetto topico: Cancer - Research
Clinical trials
Soggetto genere / forma: Electronic books.
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references.
Nota di contenuto: Front Cover; Contents; Preface; Chapter 1 Introduction; Chapter 2 Single-Arm Phase II Trial Designs; Chapter 3 Inference on the Binomial Probability in Single-Arm Multistage Clinical Trials; Chapter 4 Single-Arm Phase II Clinical Trials with Time-to-Event Endpoints; Chapter 5 Single-Arm Phase II Trials with Heterogeneous Patient Populations: Binary and Survival Outcomes; Chapter 6 Randomized Phase II Trials for Selection: No Prospective Control Arms; Chapter 7 Randomized Phase II Cancer Clinical Trials with a Prospective Control on Binary Endpoints (I): Two-Sample Binomial Test
Chapter 8 Randomized Phase II Cancer Clinical Trials with a Prospective Control on Binary Endpoints (II): Fisher's Exact TestChapter 9 Randomized Phase II Trials with Heterogeneous Patient Populations: Stratified Fisher's Exact Test; Chapter 10 Randomized Phase II Clinical Trials Based on Survival Endpoints: Two-Sample Log-Rank Test; Chapter 11 Some Flexible Phase II Clinical Trial Designs; Back Cover
Sommario/riassunto: In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an experimental therapy with a prospective control therapy. Randomized Phase II Cancer Clinical Trials explains how to properly select and accurately use diverse statistical metho
Titolo autorizzato: Randomized phase II cancer clinical trials  Visualizza cluster
ISBN: 0-429-06447-0
1-4398-7186-8
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910463246803321
Lo trovi qui: Univ. Federico II
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Serie: Chapman & Hall/CRC biostatistics series (Unnumbered)