Chordomas and chondrosarcomas of the skull base and spine / / edited by Griffith R. Harsh, Francisco Vaz-Guimaraes

• Pubblicazione: London, : Academic Press, 2018
• Edizione: Second edition.
• Descrizione fisica: xix, 463 p. : ill. (chiefly col.) ; ; 29 cm
• Disciplina: 616.99491
• Soggetto topico: Skull Base Neoplasms; Spine - Cancer
• Altri autori: HarshGriffith R., IV. Vaz-GuimaraesFrancisco BilskyMark H (MSKCC.) LauferIlya (MSKCC.) LockneyNatalie Ausborn (MSKCC.) SchmittAdam Michael (MSKCC.) YamadaJosh (MSKCC.)
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Front Cover -- CHORDOMAS AND CHONDROSARCOMAS OF THE SKULL BASE AND SPINE -- CHORDOMAS AND CHONDROSARCOMAS OF THE SKULL BASE AND SPINE -- Copyright -- Dedication -- Contents -- List of Contributors -- Foreword -- Preface -- I - EMBRYOLOGY, PATHOLOGY,AND MOLECULAR BIOLOGY -- 1 - Embryology of the Skull Base and Vertebral Column -- INTRODUCTION -- THE SKULL BASE -- Genetic Control of Skull Base Development -- Embryology of the Skull Base -- EMBRYOLOGICAL DEVELOPMENT OF THE NOTOCHORD AND VERTEBRAL COLUMN -- References -- 2 - Pathology of Chordoma and Chondrosarcoma of the Axial Skeleton -- CHORDOMA -- INTRODUCTION -- EPIDEMIOLOGY -- CLASSIFICATION AND PATHOLOGY -- Conventional Chordoma -- Chondroid Chordoma -- Dedifferentiated Chordoma -- CYTOGENETICS -- PROGNOSTICALLY AND THERAPEUTICALLY SIGNIFICANT PATHOLOGICAL FEATURES -- CHONDROSARCOMA -- INTRODUCTION -- EPIDEMIOLOGY -- CLASSIFICATION AND PATHOLOGY -- References -- Further Reading -- 3 - Molecular Drivers in Chordoma -- PATHOGENESIS AND MOLECULAR BIOLOGY OF CHORDOMA -- Histological Grading -- Cytogenetic Abnormalities -- Epigenetic Deregulations -- Receptor Tyrosine Kinase Signaling Pathways -- HYPOXIA AND ANGIOGENESIS IN CHORDOMA -- APOPTOSIS IN CHORDOMA -- CANCER STEM CELLS -- ANIMAL MODELS OF CHORDOMA -- MOLECULAR DRIVERS IN CHORDOMA INVASION AND METASTASIS -- SUMMARY/CONCLUSIONS -- References -- 4 - Molecular Drivers in Chondrosarcoma -- INTRODUCTION -- CLINICOPATHOLOGICAL CLASSIFICATION OF CHONDROSARCOMA -- Conventional Chondrosarcoma -- Rare Chondrosarcoma Subtypes -- MOLECULAR DRIVERS IN CHONDROSARCOMA -- Central, Dedifferentiated, and Periosteal Chondrosarcoma -- IDH1 and IDH2 Mutations -- CELLULAR CONSEQUENCES OF AN IDH1 OR IDH2 MUTATION -- IDH1 AND IDH2 MUTATIONS IN ENCHONDROMA AND CHONDROSARCOMA -- COL2A1 Mutations -- Dysregulation of the Hedgehog Pathway. ; P53 and pRb Pathway Alterations in the Progression From Low to High-Grade Chondrosarcoma -- Apoptosis and Prosurvival Pathways Implicated in Chondrosarcoma -- Peripheral Chondrosarcoma -- EXT1 and EXT2 Mutations in Osteochondroma and Peripheral Chondrosarcoma -- p53 and pRb Pathway Alterations -- Mesenchymal Chondrosarcoma: HEY1-NCOA2 Fusion -- Clear-Cell Chondrosarcoma -- SUMMARY/CONCLUSION -- References -- II - DEMOGRAPHICS, PRESENTATION,AND DIAGNOSIS -- 5 - Demographics, Presentation, and Diagnosis -- INTRODUCTION -- DEMOGRAPHICS -- Chordomas -- Chondrosarcomas -- PRESENTATION -- Skull Base Tumors -- Spinal Tumors -- Pediatric Cases -- DIAGNOSIS -- Diagnostic Approach to Skull Base Tumors -- Diagnostic Approach to Spinal Tumors -- CONCLUSIONS -- References -- 6 - Differential Diagnosis of Clival and Spinal Tumors -- INTRODUCTION -- CONGENITAL TUMORS -- Ecchordosis Physaliphora -- Benign Notochordal Cell Tumor -- PRIMARY CARTILAGINOUS TUMORS -- Chondroma -- Chondroblastoma -- PRIMARY OSSEOUS TUMORS -- Osteoma and Osteoblastoma -- Osteosarcoma -- Giant Cell Tumor -- Intraosseous Hemangioma -- CENTRAL NERVOUS SYSTEM TUMORS -- Schwannoma -- Pituitary Macroadenoma -- SECONDARY NEOPLASTIC TUMORS -- Metastatic Carcinoma -- Hematological Malignancies -- Plasma Cell Neoplasms -- Langerhans Cell Histiocytosis -- Adult T-cell Leukemia/Lymphoma -- Hodgkin and Non-Hodgkin Lymphomas -- Nasopharyngeal Carcinoma -- NONNEOPLASTIC TUMORS -- Aneurysmal Bone Cyst -- Fibrous Dysplasia -- OTHER TUMORS -- References -- 7 - Imaging Cranial Base Chordoma and Chondrosarcoma -- IMAGING TECHNIQUE -- PART I: CHORDOMA -- PART II: CHONDROSARCOMA -- PART III: POTENTIALLY CONFOUNDING LESIONS -- References -- Further Reading -- 8 - Imaging Chordoma and Chondrosarcoma of the Vertebrae and Sacrum -- PART I: CHORDOMA -- PART II: CHONDROSARCOMA. ; PART III: POTENTIALLY CONFOUNDING LESIONS -- References -- Additional Reading -- III - SURGERY OF SKULL BASE TUMORS -- 9 - Surgical Anatomy of the Skull Base -- INTRODUCTION -- GENERAL SKULL BASE ANATOMY2 -- Anterior Skull Base (Fig. 9.1) -- Middle Skull Base (Fig. 9.2) -- Posterior Skull Base (Fig. 9.3) -- ESSENTIAL ENDOSCOPIC ENDONASAL ANATOMY: THE SPHENOID BONE, SPHENOID SINUS, AND PITUITARY GLAND (FIG. 9.4) -- Sphenoid Bone -- The Sphenoid Sinus -- The Pituitary Gland and Suprasellar Space -- ANATOMY OF THE CLIVUS AND ENVIRONS -- General -- Surgical Subdivision of the Clivus (Fig. 9.5) -- Upper Clivus (Fig. 9.6) -- Middle Clivus (Fig. 9.7) -- Lower Clivus (Fig. 9.8) -- References -- 10 - Skull Base Tumors: Surgical Considerations -- INTRODUCTION -- TREATMENT STRATEGIES -- SKULL BASE SURGICAL PRINCIPLES -- PREOPERATIVE ASSESSMENT -- CHOICE OF APPROACH: ANATOMIC CONSIDERATIONS -- SURGICAL CORRIDORS TO ANATOMICALLY DISTINCT MODULES OF THE SKULL BASE -- ANTERIOR APPROACHES TO CLIVAL TUMORS -- Subfrontal Approaches -- Transfacial Approaches -- Transfacial-Transnasal Approaches -- Transfacial-Transoral Approaches -- Endoscopic Endonasal Approaches -- LATERAL APPROACHES TO CLIVAL AND PETROUS TUMORS -- Anterolateral Corridor -- Lateral Corridor -- Lateral-Inferior Corridor -- Posterolateral Corridor -- Inferior-Posterolateral Corridor -- CONCLUSIONS -- References -- 11 - Midline Subfrontal Approaches: The Transbasal Approach and Extended Modifications to Access the Clivus -- INTRODUCTION -- SURGICAL CONSIDERATIONS: SELECTION OF APPROACH -- PREOPERATIVE CONSIDERATIONS -- SURGICAL POSITIONING -- SKIN INCISION -- STANDARD BIFRONTAL TRANSBASAL APPROACH -- EXTENDED TRANSBASAL APPROACHES -- Level 1 Transbasal Approach -- Level 2 Transbasal Approach -- Level 3 Transbasal Approach -- MODIFIED ONE-PIECE EXTENDED TRANSBASAL APPROACH -- SUBCRANIAL APPROACH. ; COMBINED TRANSBASAL AND ENDOSCOPIC ENDONASAL APPROACH -- RECONSTRUCTION -- POSTOPERATIVE MANAGEMENT -- CONCLUSION -- References -- 12 - The Endoscopic Endonasal Approach to Chordomas and Chondrosarcomas -- INTRODUCTION -- ANATOMY-ENDONASAL PERSPECTIVE -- INDICATIONS AND PREOPERATIVE PLANNING -- APPROACH -- SINUS/NASAL PHASE -- TRANSMAXILLARY APPROACHES -- UPPER CLIVUS -- MID-CLIVUS -- LOWER CLIVUS/CRANIOCERVICAL JUNCTION -- PETROUS APEX/PETROCLIVAL JUNCTION/CAVERNOUS SINUS/OCCIPITAL CONDYLE (CORONAL PLANE) -- LIMITATIONS -- RECONSTRUCTION -- POSTOPERATIVE CARE -- RESULTS -- CONCLUSION -- References -- 13 - Transoral Approaches to Midline Skull Base Tumors -- SUMMARY -- References -- 14 - Chordomas and Chondrosarcomas of the Skull Base: Anterolateral Approaches -- INTRODUCTION -- INDICATIONS AND PREOPERATIVE PLANNING -- Endoscopic Versus Open Approaches -- Radiographic Evaluation -- Surgical Goals -- SURGICAL TECHNIQUE AND COMPLICATION AVOIDANCE -- Parasellar Region Anatomy -- Frontotemporal-Orbitozygomatic Approach -- Bony Cuts -- Cavernous Sinus Access -- Anterior Petrosectomy -- Principles of Tumor Resection -- POSTOPERATIVE CARE -- RESULTS -- Anterolateral Approach-Related Complications -- CONCLUSIONS -- References -- Further Reading -- 15 - Lateral Approaches -- MIDDLE CRANIAL FOSSA APPROACH -- EXTENDED MIDDLE CRANIAL FOSSA APPROACH -- PREOPERATIVE CONSIDERATIONS -- PATIENT POSITION AND MONITORING -- EXTRADURAL EXPOSURE -- INTRADURAL PETROUS APICECTOMY -- EXTRADURAL PETROUS APICECTOMY -- TUMOR REMOVAL -- RECONSTRUCTION -- POTENTIAL COMPLICATIONS -- COMBINATION WITH OTHER APPROACHES -- BENEFITS OF THE INTRADURAL OPTION -- CASE GROUP (INTRADURAL OPTION) -- BENEFITS OF THE EXTRADURAL OPTION -- CASE EXAMPLE (EXTRADURAL OPTION) -- References -- 16 - Subtemporal-Preauricular Approach to the Infratemporal Fossa -- BACKGROUND. ; APPLICATION OF THE APPROACH -- Indications -- Limitations -- Advantages -- Disadvantages -- PREOPERATIVE EVALUATION AND PLANNING -- OPERATIVE APPROACH -- Pitfalls -- CLOSURE AND RECONSTRUCTION -- CASE 1 -- CASE 2 -- CASE 3 -- References -- 17 - Chordomas and Chondrosarcomas of the Skull Base: Transpetrosal Approaches -- INDICATIONS AND PREOPERATIVE PLANNING -- SURGICAL TECHNIQUES COMMON TO ALL TRANSPETROSAL APPROACHES -- Transpetrosal (Retrolabyrinthine, Translabyrinthine, Transcochlear) -- Retrolabyrinthine -- Translabyrinthine -- Transcochlear -- Transjugular -- Combined (Middle Fossa and Transpetrosal, Transpetrosal and Far Lateral, Subtemporal Transpetrous Apex) -- Middle Fossa and Transpetrosal -- Transpetrosal and Far Lateral Approach to Foramen Magnum -- Subtemporal Transpetrous Apex -- POSTOPERATIVE CARE -- RESULTS -- ILLUSTRATIVE CASES -- CONCLUSIONS -- References -- 18 - Chordomas and Chondrosarcomas of the Skull Base: Retrosigmoid Approaches -- INTRODUCTION -- INDICATIONS AND PREOPERATIVE PLANNING -- SURGICAL TECHNIQUES AND COMPLICATION AVOIDANCE -- POSTOPERATIVE CARE -- RESULTS -- CONCLUSIONS -- References -- 19 - The Extreme Lateral Approach for Chordomas and Chondrosarcomas of the Craniovertebral Junction -- INTRODUCTION -- PATHOPHYSIOLOGY -- SURGICAL ANATOMY -- INDICATIONS -- PREOPERATIVE EVALUATION -- OPERATIVE PROCEDURE -- Intraoperative Monitoring -- Positioning -- Skin Incision and Soft Tissue Dissection -- Exposure and Isolation of the Vertebral Artery -- Bone Removal -- Tumor Resection -- Closure -- Stability of the Craniovertebral Junction -- DISCUSSION -- Case Example 1 -- Case Example 2 -- CONCLUSION -- References -- 20 - Staged Approaches for Large Skull Base Chordomas and Chondrosarcomas -- INTRODUCTION -- PREOPERATIVE PLANNING -- Surgical Strategies -- Anterior Approaches for Midline Tumors -- Endoscopic-Assisted Techniques. ; Transsphenoidal and Extended Transsphenoidal Approach.
• Titolo autorizzato: Chordomas and chondrosarcomas of the skull base and spine
• ISBN: 0-12-804333-4; 0-12-804257-5
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910583463703321
• Lo trovi qui: Univ. Federico II