Acne : current concepts and management / / Dae Hun Suh, editor

• Pubblicazione: Cham, Switzerland : , : Springer, , [2021]; ℗♭2021
• Descrizione fisica: 1 online resource (194 pages)
• Disciplina: 616.53
• Soggetto topico: Acne - Treatment; Acne; Terapèutica
• Soggetto genere / forma: Llibres electrònics
• Persona (resp. second.): SuhDae Hun
• Nota di contenuto: Intro -- Preface -- Contents -- Contributors -- 1: Update on Cutibacterium acnes -- Introduction -- Cutibacterium acnes (Ex - Propionibacterium acnes) Identity Passport -- Bacteriological Description -- Ecological Niches -- Taxonomy Modification -- Phylogeny -- Growth Culture Conditions -- Virulence Factors -- Resistance in Acne Context -- Acne in the Genomic Era -- Cutibacterium acnes and Cutaneous Microbiome Interactions -- Cutibacterium acnes and Innate Immunity -- What Alternatives in the Future? -- Microbiome and Probiotics Approach -- Phage Therapy Approach -- Vaccine Approach -- Conclusion -- References -- 2: Updates in Isotretinoin -- Introduction -- Dosing -- Laboratory Monitoring -- Depression -- Procedures -- Conclusion -- References -- 3: Developing a Core Outcome Set for Acne Clinical Trials: Towards Standardization and Harmonization -- Why Perform Interventional Clinical Trials? -- Measurement Issues in Clinical Trials -- Issue with Acne Clinical Trials -- Regulatory Guidance -- Need for Standardization -- What Are Core Outcome Sets? -- Core Outcome Sets in Dermatology -- Process of Determining Acne Core Domains -- Summary -- References -- 4: Adult Acne Vulgaris -- Epidemiology and Characteristics of Adult Acne -- Pathogenesis of Adult Acne -- Genetics -- Dysbiosis -- Insulin-Like Growth Factor 1 -- Diagnostic Considerations and Patient Evaluation in Adult Acne -- Acne Distribution and Severity Grading in Adult Acne -- Severe Adult Acne and Associated Syndromes -- Autoinflammatory Syndromes -- Disorders of Endocrine Metabolism -- Dietary Factors in Adult Acne -- Approach to Evaluation of Adults with Acne -- Therapeutic Options for Adult Acne -- Topical Dapsone -- Oral Anti-androgens -- Combined Oral Contraceptive Pills -- Oral Spironolactone -- Oral Metformin -- Laser and Light Therapies for Adult Acne. ; Treatment of Adult Acne During Pregnancy and Lactation -- Comparison of Guidelines on Adult Acne -- Prognosis and Long-Term Outcomes -- Conclusion -- References -- 5: Topical Retinoids and Acne -- Introduction -- Structure and Mechanism of Action -- All-Trans Retinol and All-Trans Retinoic Acid -- Adapalene -- Tazarotene -- Trifarotene -- Combination Therapies -- Adverse Effects -- Topical Retinoids in the Treatment of Acne Sequelae -- References -- 6: New Drug Developments in Acne -- Introduction -- Limitations of Acne Treatment -- Methodology -- New Drug Developments in Acne -- Topical Drugs -- Effects on Sebum Production -- Effects on Follicular Hyperkeratosis -- Effects on the Microbiota -- Systemic Acne Drugs Under Investigation in Phase 1 and 2 Trials -- Effects on Sebum Production -- Effects on the Microbiota -- Biologics with Different Actions in Acne -- Further Agents with Anti-inflammatory Effects -- Other Systemic Compounds Under Investigation -- Summary -- References -- 7: Scientific Connection Between Acne and Diet -- References -- 8: Photodynamic Therapy for Acne Vulgaris: Mechanism and Clinical Practice -- Mechanism of PDT in Acne -- PDT on Sebaceous Glands -- Antimicrobial Effects -- Anti-inflammation Effects -- Clinical Practice of PDT in Acne -- Photosensitizer -- Light Source -- Incubation Time -- Skin Preparation -- Adverse Effects -- Conclusion -- References -- 9: Insulin Resistance Associated Acne -- Molecular Aspects of IRAA -- Racial, Ethnic, Regional, Geographic Aspects of IRAA -- Clinical Profile of IRAA -- Companion Morphologies in IRAA -- IRAA Comorbidities -- Pathogenesis of IRAA -- Laboratory Validation of IRAA -- Treatment of IRAA -- References -- 10: Acne Fulminans -- Introduction -- Epidemiology -- Pathogenesis -- Associated Disorders -- Classification -- Clinical Presentation -- Histology -- Laboratory Findings. ; Imaging -- Differential Diagnosis -- Treatment -- Systemic Treatment -- Miscellaneous -- Topical Treatment -- Physical Treatment -- References -- 11: Acne and Environmental Factors -- Introduction -- Chloracne -- Cigarette Smoking and Acne -- Coal Tar Acne -- UV and Acne -- Conclusions -- References -- 12: Acne on Pigmented Skin -- References -- 13: Up-to-Date Therapeutic Approaches for Acne Scars in a Korean Dermatology Clinic -- Introduction -- Treatment Modalities -- Overview of Fractional Laser Technology -- Non-ablative Fractional Laser (NAFL) -- Ablative Fractional Laser (AFL) -- Picosecond Lasers with a Diffractive Optic Element (P-DOE) -- Fractional Microneedling Radiofrequency (FMR) -- Chemical Peeling -- Mini-surgical Techniques -- Transcutaneous Pneumatic Injection of Solutions -- Fillers -- Autologous Fibroblast Transplantation -- Biologic Materials -- Treatments for Hypertrophic Scars and Keloidal Acne Scars -- Practical Perspectives for "Real-World" Treatments: Author's Opinion -- Multimodal Approaches for Individual Atrophic Scar Subtypes -- Common Procedures -- Ice Pick Scars -- Rolling Scars -- Boxcar Scars -- Hypertrophic and Keloidal Scars -- Acne Scar Related to Dyschromia -- Concurrent Treatments with Active Acne -- Conclusion -- References -- 14: Innate and Adaptive Immunity in Acne Vulgaris -- Introduction -- Immune Events Are Crucial in All Stages of Acne Pathogenesis -- Discovery of the Immune Properties of Keratinocytes -- Innate Immune Events -- The Role of Keratinocytes in Acne Pathogenesis -- Sebocytes Are Active Players in Acne Immunity Too -- Adaptive Immune Regulation in Acne -- Not All C. acnes Strains Are Created to Be Equal? -- Acne Has a Complex Pathogenesis -- Literature -- 15: Clinical Features and Differential Diagnosis of Acne Vulgaris -- The Purpose of This Chapter -- Clinical Features of Acne Vulgaris. ; Special Forms of Acne -- Neonatal Acne, Acne Neonatorum (Fig. 15.1) -- Acne Conglobata -- Acne Fulminans -- Cosmetic Acne Including Pomade Acne -- Acne Excoriee (Fig. 15.2) -- Steroid Acne -- Chloracne Including Dioxin Acne -- Other Drug-Induced Acnes -- Hormonal Acne (Fig. 15.3) -- SAPHO, PAPA, PASH, and PAPASH Syndromes -- Clinical Differential Diagnosis of Acne -- Rosacea (Fig. 15.4) -- Perioral Dermatitis (Fig. 15.5) -- Folliculitis -- Malassezia Folliculitis (Fig. 15.6) -- Demodicosis (Fig. 15.7) -- Folliculitis Barbae -- Pseudofolliculitis Barbae -- Eosinophilic Pustular Folliculitis (Ofuji Disease) -- Acneiform Eruption Due to Anti-EGFR Drugs or Other Anticancer Drugs (Figs. 15.8 and 15.9) -- Lupus Miliaris Disseminatus Faciei -- Milium -- Angiofibroma (Tuberous Sclerosis) (Fig. 15.10) -- Syringomas -- Flat Warts (Fig. 15.11) -- Others -- Conclusion -- References -- 16: Epidemiology of Acne in Latin America and Research News from Brazil -- Acne Vulgaris -- Inflammation -- Classification -- Prevalence and Clinical Forms -- Quality of Life -- Algorithm of Treatment -- Oral Isotretinoin -- Controversies About Oral Isotretinoin -- Brazilian Similar Product -- Adult Female Acne -- Epidemiology in Latin America -- Quality of Life -- Inflammation: Molecular Mechanism -- Hormonal Metabolism -- Practical Guide for Management -- References -- 17: Androgens and Acne -- Introduction -- Androgen-Related Pathophysiology of AV -- Androgens and Altered Sebum Production and Composition -- Androgens in Epidermal Dyskeratinization in Hair Follicles -- Androgens in Cutaneous Inflammation -- Androgen-Related Clinical Implications -- Anabolic-Androgenic Steroid-Induced Acne in Bodybuilders -- Androgen-Induced Acne in Transgender Men -- Acne in Androgen-Mediated Conditions (Polycystic Ovarian Syndrome, PCOS) -- Antiandrogenic Treatments in AV -- Conclusion. ; References -- Index.
• Titolo autorizzato: Acne
• ISBN: 3-030-68996-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910495214103321
• Lo trovi qui: Univ. Federico II
• Serie: Updates in clinical dermatology.