Intracellular Delivery II : Fundamentals and Applications / / edited by Aleš Prokop, Yasuhiko Iwasaki, Atsushi Harada

• Pubblicazione: Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
• Edizione: 1st ed. 2014.
• Descrizione fisica: 1 online resource (479 p.)
• Disciplina: 615.6
• Soggetto topico: Cancer research; Cell biology; Nanotechnology; Applied mathematics; Engineering mathematics; Bioorganic chemistry; Pharmacy; Cancer Research; Cell Biology; Mathematical and Computational Engineering; Bioorganic Chemistry
• Persona (resp. second.): ProkopAleš; IwasakiYasuhiko; HaradaAtsushi
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Editorial and Introduction to Volume 2 -- Part I Novel nanocarrier design and processing -- Proprietary nanofiber technologies and scale-up -- Magnetically responsive (nano)biocomposites.-Zwitterionic nanocarriers for gene delivery -- Stimuli-responsive polymeric nanocarriers as promising drug and gene delivery systems -- Photo-responsive polymeric nanocarriers for on-demand drug delivery -- Part II Nanocarrier characterization and function -- Considerations on uptake and intracellular trafficking of nanocarriers -- Mucus as physiological barrier to intracellular delivery -- Investigation of nanoparticles in biological objects by electron microscopy techniques -- Gold nanoparticles for high resolution imaging in modern immunocytochemistry -- Design of functional polymers for intracellular drug nucleic acids delivery -- Membrane-domain-selective drug targeting based on lipid modification -- Multifuntional protein-based nanoparticles for theragnosis -- Cytocompatible phospholipid polymer for noninvasive nanodevice -- Intracellular protein delivery using self-assembled amphiphilic polysaccharide nanogels -- Part III Simulation for delivery and function -- Molecular dynamics simulations of polyplexes and lipoplexes -- Computational studies of highly pegylated sterically stabilized micelles self-assembly and drug solubilization -- Toward intracellular delivery and drug discovery,Stochastic logic networks as efficient computational models for gene regulatory networks -- Part IV Nanocarriers for drug discovery and treatment -- Nanodiamonds as intracellular probes for imaging in biology and medicine -- Intracellular delivery of RNA using RNA-binding proteins or peptides -- Hyaluronic acid based nanofibers for wound dressing and drug delivery carriers -- Potential of siRNA therapy in chronic myeloid leukemia.
• Sommario/riassunto: This volume is a continuation of Volume 1 following the previously published Editorial. More emphasis is given to novel nanocarrier designs, their characterization and function, and applications for drug discovery and treatment. A number of chapters will deal with nanofibers as a new major application within the biomedical field with a very high success rate particularly in wound healing and diabetic foot and spine injuries. A major new subdivision will deal with mathematical methods for the assembly of nanocarriers both for simulation and function.
• Titolo autorizzato: Intracellular Delivery II
• ISBN: 94-017-8896-0
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298320503321
• Lo trovi qui: Univ. Federico II
• Serie: Fundamental Biomedical Technologies, . 1559-7083 ; ; 7