Cancer gene therapy by viral and non-viral vectors / / edited by Malcolm K. Brenner, Mien-Chie Hung
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| Titolo: |
Cancer gene therapy by viral and non-viral vectors / / edited by Malcolm K. Brenner, Mien-Chie Hung
|
| Pubblicazione: | Hoboken, New Jersey : , : Wiley, , 2014 |
| ©2014 | |
| Descrizione fisica: | 1 online resource (176 p.) |
| Disciplina: | 616.042 |
| Soggetto topico: | Gene therapy |
| Altri autori: |
BrennerMalcolm K. <1951->
HungMien-chie
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references at the end of each chapters and index. |
| Nota di contenuto: | Machine generated contents note: ContributorsSeries ForewordPreface Part I: Delivery Systems 1. Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors Vincenzo Cerullo, Kilian Guse, Markus Vaha-Koskela and Akseli Hemminki 2. Retroviruses for Cancer Therapy Jiehua Zhou, Yue Ding, John Burnett and John Rossi 3. DNA Plasmids for Non-viral Gene Therapy of Cancer Amer N. Najjar, Judy S.E. Moyes and Laurence J.N. Cooper 4. Cancer Therapy with RNAi delivered by Nonviral Membrane/Core Nanoparticles Andrew B. Satterlee and Leaf Huang Part II: Targeted Expression 5. Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promoters Jennifer L. Hsu, Longfei Huo, Chia-Wei Li, Yi-Hsin Hsu, Yan Wang and Mien-Chie Hung 6. MicroRNAs as Drugs and Drug Targets in Cancer Hui Ling and George A. Calin Part III: Principles of Clinical Trials in Gene Therapy 7. Regulatory Issues for Manufacturers of Viral Vectors and Vector-Transduced Cells for Phase I/II Trials Adrian P. Gee and Zhuyong Mei 8. U.S. Regulations Governing Clinical Trials in Gene Therapy Bambi Grilley 9. Remaining Obstacles to the Success of Cancer Gene Therapy Malcolm K. BrennerIndex. |
| Sommario/riassunto: | Translational medicine has opened the gateway to the era of personalized medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. Gene therapy in cancer has faced many technical barriers in the past but has recently shown significant progress that could allow stem cell and gene transfer therapies to make a major contribution to cancer therapy. The time appears ripe for a good, authoritative, book-length review of the state-of-the-ar |
| Titolo autorizzato: | Cancer gene therapy by viral and non-viral vectors |
| ISBN: | 1-118-50165-9 |
| 1-118-50166-7 | |
| 1-118-50164-0 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910818121503321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Translational oncology (Series) ; ; 4.