Diagnostic pediatric hematopathology / / edited by Maria A. Proytcheva [[electronic resource]]

• Pubblicazione: Cambridge : , : Cambridge University Press, , 2011
• Descrizione fisica: 1 online resource (xi, 577 pages) : digital, PDF file(s)
• Disciplina: 618.9215
• Soggetto topico: Pediatric hematology; Blood - Diseases - Diagnosis; Children - Diseases - Diagnosis
• Persona (resp. second.): ProytchevaMaria A.
• Note generali: Title from publisher's bibliographic system (viewed on 05 Oct 2015).
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover; Diagnostic Pediatric Hematopathology; Title; Copyright; Dedication; Contents; Contributors; Acknowledgements; Introduction; Section 1: General and non-neoplastic hematopathology; Chapter 1: Hematologic values in the healthy fetus, neonate, and child; Developmental hematopoiesis: a general view; Composition of fetal blood; Hematologic values in term neonates and infants; Hematologic values in small-for-gestational-age (SGA) term newborns; Hematologic values in preterm neonates; Hematologic values during early childhood and in older children ; Preanalytical issues related to pediatric blood samplesLimited blood availability; Effect of blood sampling site on the hematology test results; Effect of exertion and violent crying on the white blood cell count; Other preanalytical factors affecting hematologic test results in neonates; Analytical issues related to pediatric blood samples; Interpretation of hematologic test results in children; Other factors affecting neonatal testing; Chapter 2: Normal bone marrow; Ontogeny of the hematopoietic system; Postnatal bone marrow; Age-specific differences in the bone marrow ; Bone marrow examination in childrenReferences; Chapter 3: Disorders of erythrocyte production: Nutritional deficiencies, iron deficient, and sideroblastic anemia; Introduction; Iron; Dietary iron; Iron transport; Iron uptake from the intestine; Iron uptake from the plasma; Iron storage; Iron regulation; Hemoglobin synthesis; Age and iron needs; Iron in the first year; Iron in the diet; Assessment of iron status; Ferritin; Serum iron and transferrin; Zinc protoporphyrin; Soluble transferrin receptor; Treatment of iron deficiency; Vitamin B12; Role in the body; Dietary vitamin B12 ; Vitamin B12 absorption and metabolismVitamin B12 deficiency; Maternal vitamin B12 deficiency; Inherited disorders of transport and absorption of vitamin B12; Inborn errors of metabolism; Methylmalonyl-CoA mutase deficiency; Adenosylcobalamin deficiency; Methylcobalamin deficiency; Combined deficiencies; Acquired vitamin B12 deficiency; Assessment; Treatment; Folate; Role in the body; Dietary folate and folic acid; Folate absorption and metabolism; Folate deficiency; Pregnancy; Malabsorption; Increased utilization of folate; Drugs; Inherited disorders of transport and metabolism; Assessment ; TreatmentSideroblastic anemia; References; Chapter 4: Disorders of hemoglobin synthesis: Thalassemias and structural hemoglobinopathies; Normal hemoglobins; Structure and function of hemoglobin; Genetics and transcription control of hemoglobin; Disorders of hemoglobin synthesis; Overview; Population genetics; Thalassemias; Alpha-thalassemias; Beta-thalassemias; Delta-beta-thalassemias; Structural hemoglobinopathies; Hemoglobin S; Hemoglobin C, hemoglobin D, and other rare hemoglobinopathies; Interactions of structural hemoglobinopathies with thalassemias; Laboratory evaluation; Introduction ; Effects of hemoglobinopathies on general laboratory tests
• Sommario/riassunto: Diagnostic Pediatric Hematopathology is unique in providing an accurate and up-to-date guide to the diagnosis of benign and malignant hematologic disorders of childhood. The text discusses the development of the hematopoietic and lymphoid systems - and how this affects normal and abnormal findings in children at various ages. Also examined are the morphologic, immunophenotypic, cytogenetic, and molecular genetic characteristics of most pediatric-specific hematologic diseases. This is an excellent reference that ensures accurate diagnoses when evaluating peripheral blood, bone marrow, and lymph nodes of children. The text is written by a team of experienced pediatric hematopathologists and clinical scientists drawn from major academic children's hospitals in the United States, Europe, and Canada. It will be a valuable tool in the every day practice of pathologists, pediatric pathologists, and hematopathologists, and a ready educational resource for fellows, pathology residents, medical students, clinical scientists in the field, and pediatric hematologists/oncologists.
• Titolo autorizzato: Diagnostic pediatric hematopathology
• ISBN: 1-107-21901-9; 1-280-77582-3; 0-511-91811-9; 9786613686213; 0-511-91713-9; 0-511-91909-3; 0-511-78129-6; 0-511-91532-2
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910789623603321
• Lo trovi qui: Univ. Federico II