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Breast Cancer: From Bench to Personalized Medicine / / edited by Saima Shakil Malik, Nosheen Masood



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Titolo: Breast Cancer: From Bench to Personalized Medicine / / edited by Saima Shakil Malik, Nosheen Masood Visualizza cluster
Pubblicazione: Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2022
Edizione: 1st ed. 2022.
Descrizione fisica: 1 online resource (534 pages)
Disciplina: 616.9449
Soggetto topico: Cancer
Cancer - Epidemiology
Cancer - Genetic aspects
Cancer Biology
Cancer Epidemiology
Cancer Genetics and Genomics
Persona (resp. second.): MalikSaima Shakil
MasoodNosheen
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: Module 1_Overview of Breast Cancer -- Module 2_Cell and Molecular Biology of Breast Cancer-Diagnosis and Prognosis -- Module 3_Breast Cancer Treatment.
Sommario/riassunto: This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.
Titolo autorizzato: Breast Cancer  Visualizza cluster
ISBN: 981-19-0197-X
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910568287503321
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Serie: Biomedical and Life Sciences Series