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Essentials of nuclear medicine physics, instrumentation, and radiation biology / / Rachel A. Powsner, Matthew R. Palmer, Edward R. Powsner



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Autore: Powsner Rachel A. Visualizza persona
Titolo: Essentials of nuclear medicine physics, instrumentation, and radiation biology / / Rachel A. Powsner, Matthew R. Palmer, Edward R. Powsner Visualizza cluster
Pubblicazione: Hoboken, New Jersey : , : Wiley-Blackwell, , [2021]
©2021
Edizione: Fourth edition.
Descrizione fisica: 1 online resource (301 pages)
Disciplina: 616.07575
Soggetto topico: Ionizing radiation
Medical physics
Soggetto genere / forma: Electronic books.
Persona (resp. second.): PowsnerEdward R. <1926->
PalmerMatthew R. <1958->
Note generali: Preceded by: Essentials of nuclear medicine physics and instrumentation / Rachel A. Powsner, Matthew R. Palmer, Edward R. Powsner. Third edition. Chichester, West Sussex, UK : Wiley-Blackwell, 2013.
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgments -- Chapter 1. Basic Nuclear Medicine Physics -- Properties and structure of matter -- Atomic structure -- Radioactivity -- Decay notation -- Half-life -- Questions -- Answers -- Chapter 2. Interaction of Radiation with Matter -- Interaction of photons with matter -- Types of photon interactions in matter -- Attenuation of photons in matter -- Interaction of charged particles with matter -- Excitation -- Ionization -- Annihilation -- Bremsstrahlung -- Reference -- Questions -- Answers -- Chapter 3. Formation of Radionuclides -- Generators -- Activity curves for generators -- Cyclotrons -- Reactors -- Reactor basics -- Fission -- Neutron capture -- Questions -- Answers -- Chapter 4. Nonscintillation Detectors -- Gas-filled detectors -- Principles of measurement -- Characteristics of the major voltage regions applied across a gas-filled detector -- Sensitivity -- Types of gas-filled detector -- Semiconductor detectors -- Introduction -- Semiconductor materials -- Photographic and luminescent detectors -- Photographic detectors -- Thermoluminescent and optically luminescent detectors -- Questions -- Answers -- Chapter 5. Scintillation Detectors -- Structure -- Scintillation crystals -- Photomultiplier tubes -- Amplifiers -- Pulse-height analyzer -- Sodium iodide detector energy spectrum -- Photopeak -- Effect of surrounding matter on the energy spectrum -- Characteristics of scintillation detectors -- Energy resolution -- Decay time -- Efficiency -- Types of scintillation-based detectors -- Thyroid probe -- Well counter -- Liquid scintillation counters -- Dosimeters and area monitors -- Questions -- Answers -- Chapter 6. Imaging Instrumentation -- Theory and structure -- Components of the imaging system -- Planar imaging -- Image acquisition -- Questions -- Answers.
Chapter 7. Single-photon Emission Computed Tomography (SPECT) -- Equipment -- Types of camera -- Angle of rotation of heads -- Two-headed cameras: fixed and adjustable -- Acquisition -- Arc of acquisition -- Number of projection tomographic views -- Collection times -- Step-and-shoot vs. continuous acquisition -- Patient motion and sinograms -- Dedicated cardiac SPECT cameras -- Quantitation of lesion activity in SPECT studies -- Questions -- Chapter 8. Positron Emission Tomography (PET) -- Advantages of PET imaging -- Sensitivity -- Resolution -- Radiopharmaceuticals -- PET camera components -- Crystals -- Photomultipliers -- Pulse-height analyzers, timing discriminators, and coincidence circuits -- Septa -- Factors affecting resolution in PET imaging -- Positron range in tissue -- Parallax error -- Attenuation in PET imaging -- Attenuation correction -- Standard uptake values -- References -- Questions -- Chapter 9. X-ray Computed Tomography (CT) -- X-ray production -- X-ray imaging -- Computed tomography -- Overview -- Multislice detector configuration -- Axial and helical scanning -- Hounsfield units -- Questions -- Chapter 10. Magnetic Resonance Imaging (MRI) -- Background -- Spin -- Magnetism -- Magnetic moments -- Introduction to MRI -- Application of the magnetic field -- Application of radiofrequency pulses -- The MR signal -- Signal readout: spin-echo and inversion-recovery -- Signal localization -- Contrast manipulation in MR imaging -- MRI scanner -- References -- Chapter 11. Hybrid Imaging Systems: PET-CT, SPECT-CT, and PET-MRI -- PET-CT and SPECT-CT imaging -- PET-CT -- SPECT-CT -- Current limitations in SPECT-CT and PET-CT hybrid imaging -- Breathing artifacts -- Contrast agent artifacts -- PET-MR imaging -- Introduction -- PET-MR scanner design -- Attenuation correction -- Questions -- Answers.
Chapter 12. Image Reconstruction, Processing, and Display -- Reconstruction -- Filtered backprojection -- Iterative reconstruction -- Resolution recovery -- Postreconstruction image processing -- Multiplanar reformatting -- Advanced display techniques -- Questions -- Answers -- Chapter 13. Information Technology -- Network -- DICOM -- PACS -- Information systems -- Additional DICOM capabilities -- Questions -- Answers -- Chapter 14. Quality Control -- Nonimaging devices -- Survey meters -- Crystal scintillation detectors: well counters and thyroid probes -- Chi-square test -- Imaging -- Planar gamma camera -- SPECT -- PET -- Image quality -- CT -- Spatial (high-contrast) resolution -- Hybrid system testing -- Reference -- Chapter 15. Radiation Biology -- Radiation Units -- Radiation absorbed dose (rad) -- The effects of radiation on living organisms -- Cellular effects -- Tissue effects -- Heritable and cancer effects -- References -- Chapter 16. Radiation Dosimetry -- Nuclear medicine dosimetry -- Physical, biologic, and effective half-lives -- Calculation of organ doses -- Effective dose -- CT dosimetry -- Absorbed dose in CT -- Reference -- Questions -- Chapter 17. Radiation Safety -- Rationale -- Dose limits -- Occupational exposure -- Hospital workers -- Exposure to the general public -- Methods for limiting exposure -- Limiting occupational exposure -- Limiting exposure to patients -- Limiting exposure to family members and the public -- Regulations -- References -- Questions -- Chapter 18. Radiopharmaceutical Therapy -- Introduction -- Paired diagnostic and therapeutic radiopharmaceuticals -- Tissue-specific radiopharmaceutical treatments -- The thyroid gland and radioiodine -- 223Ra-dichloride and treatment of bone metastatic disease -- Radioactive 90Y-microsphere treatment of liver tumors -- Radiation protection -- Written directives.
Dose preparation -- Dose calibrator measurement of beta and alpha emitters -- Dose administration -- Post-therapy radiation precautions -- References -- Chapter 19. Management of Nuclear Event Casualties -- Interaction of radiation with tissue -- Alpha particles -- Beta particles -- Gamma rays and X-rays -- Neutrons -- Radionuclides -- Hospital response to a radiation accident -- Exposure and contamination -- Hospital facilities -- Decontamination facility -- Treatment/decontamination room for seriously wounded individuals -- External decontamination -- Patient radiation survey -- Survey meter -- Personnel -- Personal protection -- Reducing exposure -- Dosimeters -- Evaluation of the radiation accident victim -- Early estimation of whole-body radiation exposure -- Early estimation of local radiation exposure -- Acute radiation sickness -- Acute radiation syndromes -- Treatment of acute radiation sickness -- Treatment of internal contamination -- Local radiation injury to the skin -- Medical and industrial accidental overexposure -- References -- Appendix A: Common Nuclides -- Appendix B: Major Dosimetry for Common Pharmaceuticals -- Appendix C: Guide to Nuclear Regulatory Commission (NRC) Publications -- Title 10, "Energy", Code of Federal Regulations (10CFR) [1] -- NUREG - 1556, Vol. 9, Revision 3, Consolidated Guidance About Materials Licenses [2] -- References -- Appendix D: Recommended Reading by Topic -- Review of Basic Physics -- Nuclear Medicine -- Basic Nuclear Medicine Physics and Instrumentation -- PET Technology -- CT Technology -- MRI Technology -- DICOM and Information Technology -- Nuclear Medicine Quality Control -- Radiobiology -- Radiation Dosimetry -- NRC Regulations -- Therapeutics in Nuclear Medicine -- Radiation Accidents -- Index -- EULA.
Titolo autorizzato: Essentials of Nuclear Medicine Physics, Instrumentation, and Radiation Biology  Visualizza cluster
ISBN: 1-119-62101-1
1-119-62102-X
1-119-62100-3
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910555015303321
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