Emerging transplant infections : clinical challenges and implications / / Michele I. Morris, Camille Nelson Kotton and Cameron R. Wolfe (editors)

• Pubblicazione: Cham, Switzerland : , : Springer, , [2021]; ©2021
• Descrizione fisica: 1 online resource (1737 pages)
• Disciplina: 617.954
• Soggetto topico: Transplantation of organs, tissues, etc - Complications; Transplantation immunology; Infection; Transplantation Immunology; Infections; Trasplantament d'òrgans; Infeccions quirúrgiques; Immunologia de la trasplantació
• Soggetto genere / forma: Llibres electrònics
• Persona (resp. second.): MorrisMichele I.; WolfeCameron R.; KottonCamille Nelson
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Intro -- Preface -- Contents -- About the Editors -- Contributors -- Part I: General Introduction -- 1 Impact of Infection on Transplant Outcomes: Transplant Infectious Disease Expertise as an Essential Component of Transplant ... -- Introduction -- The Essential Role of Infectious Disease Specialists in the Care of Transplant Patients -- Conclusion -- References -- 2 Introduction to Immunosuppression, Tolerance, and Infection Risk -- Introduction -- T-Cell, B-Cells, and the Innate Immune System Involvement in Rejection -- Other Elements of the Immune System Involved in Transplantation -- Therapeutics Impacting Immunosuppression -- Calcineurin Inhibitors -- Antiproliferative Agents -- mTOR Inhibitors -- Corticosteroids -- Co-stimulation Blockade -- Induction Therapies -- Anti-CD25 Monoclonal Antibodies -- Anti-CD52 Monoclonal Antibodies -- Polyclonal Antibodies -- Conclusion -- Key Points -- References -- 3 Changing Definition of Immunosuppression: Targeted Therapies and Resulting Emerging Infections and Their Prevention -- Introduction -- Belatacept -- Key Findings and Suggestions -- Basiliximab -- Key Findings and Suggestions -- Rituximab and Obinutuzumab -- Key Findings and Suggestions -- Alemtuzumab -- Key Findings and Suggestions -- Eculizumab -- Key Findings and Suggestions -- Ruxolitinib -- Key Findings and Suggestions -- Ibrutinib -- Key Findings and Suggestions -- Bortezomib -- Key Findings and Suggestions -- Brentuximab -- Key Findings and Suggestions -- Conclusions -- References -- 4 Stem Cell Transplantation: Infection Risk by Transplant Type and Emerging Trends in Infection Management -- Introduction -- Risk of Infection Post-HSCT -- General Immune Reconstitution After Hematopoietic Stem Cell Transplantation -- Aplastic Period -- NK Cells and T-Cells -- B-Cells and Immunoglobulins -- Graft-Versus-Host Disease. ; Special Donor Populations -- Umbilical Cord Blood Transplantation -- Haploidentical Transplantation -- Pre-HSCT Recipient Infectious Disease Evaluation -- Prophylaxis and Management of Infection Post-HSCT -- Bacterial Infections -- Bloodstream Infections -- Diagnosis -- Management -- Gram-Positive Bacterial Infections -- Multidrug-Resistant Gram-Negative Bacterial Infections -- Bacterial Pneumonia -- Clostridioides Difficile -- Diagnosis -- Management -- Recurrent CDI -- Secondary Prophylaxis -- Fungal Infections -- Yeasts -- Disease Epidemiology -- Candida auris -- Diagnosis -- Blood Cultures -- Fungal Antigen Testing: Serum 1,3-Beta-D-Glucan -- Nanodiagnostics -- Candida auris-Specific Diagnostics -- Management -- Candida Species -- Candida auris -- Cryptococcus -- Molds -- Disease Epidemiology -- Clinical Impact -- Diagnosis -- Culture -- Galactomannan -- Aspergillus PCR -- Radiographic Studies -- Fungal Metabolite Testing -- Management -- Prophylaxis -- Treatment -- Pneumocystis Jiroveci -- Viral Infections -- Herpes Simplex Virus -- Varicella Zoster -- Cytomegalovirus -- Diagnosis -- Preemptive Management -- Prophylaxis: Shift in Management -- Drug-Resistant CMV Infection -- Epstein-Barr Virus -- Adenovirus -- BK Virus -- Parasitic Infections -- Toxoplasmosis -- Strongyloides -- Post-HSCT Vaccinations -- Conclusions -- Key Points -- Cross-References -- References -- 5 Evolving Epidemiology of Transplant Infections: Impact of Population Shifts and Climate Change -- Introduction -- Migration and Population Shift -- Modern Patterns of Human Migration and Infection -- Shifting Populations and the Changing Epidemiology of Infectious Diseases -- Preventative Strategies and Global Demographic Changes -- Climate Change and Infectious Diseases -- Climate Change and Parasitic Infections -- Climate Change and Vector-Borne Infections. ; Climate Change and Fungal Infections -- Climate Change and Bacterial Infections -- Conclusion -- Key Points -- References -- 6 Hospital Epidemiology and Infection Control in the Transplant Center -- Introduction -- Hand Hygiene -- Central Line-Associated Bloodstream Infections -- Catheter-Associated Urinary Tract Infections -- Clostridioides difficile -- Surgical Site Infections -- Preventing Infections Associated with the Healthcare Environment -- Environmental Mold -- Waterborne Pathogens -- Colonization with Multidrug-Resistant Organisms -- Respiratory Viruses -- Influenza -- Respiratory Syncytial Virus -- Adenovirus -- Other Respiratory Viruses -- Varicella-Zoster Virus -- Measles -- Healthcare Personnel Vaccination -- Conclusion -- Key Points -- Cross-References -- References -- 7 Antimicrobial Stewardship for Transplant Candidates and Recipients -- Introduction -- Implementing Antimicrobial Stewardship in Transplant Patients -- Formulary Management -- Pre-prescription Authorization and Post-prescriptive Review -- Antimicrobial Agent Selection -- Antibiotic Allergy Assessment -- Dose Optimization and Drug Interactions -- Intravenous-to-Oral Conversion -- Clinical Pathways and Guideline Development -- Diagnostic Test Stewardship -- Syndrome- and Drug-Specific Targets -- Antibiotic Stewardship -- Febrile Neutropenia -- Asymptomatic Bacteriuria in Organ Transplant Recipients -- Antiviral Stewardship -- Aerosolized Ribavirin for Management of RSV -- Cytomegalovirus (CMV) -- Antifungal Stewardship -- Antimicrobial Stewardship Program Metrics -- Conclusion -- Key Points -- References -- 8 Antimicrobial Prophylaxis in the Age of Emerging Transplant Infections -- Introduction -- Perioperative Antibacterial Prophylaxis in Solid Organ Transplantation -- Antibiotic Prophylaxis After Transplantation -- Antifungal Prophylaxis After Transplantation. ; Mycobacterial Prophylaxis After Transplantation -- Influenza Prophylaxis After Transplantation -- Herpes Simplex Virus and Varicella Zoster Virus Prophylaxis After Transplantation -- Cytomegalovirus Prophylaxis After Transplantation -- BK Polyomavirus Prophylaxis After Transplantation -- Parasitic Prophylaxis in Transplantation -- Conclusion -- Key Points -- References -- 9 Pretransplant Screening for Infection Exposure: Approach to the Patients with Epidemiologic and Geographic Risk Factors -- Introduction -- Bacterial Infections -- Bacterial Pathogens of Special Interest -- Mycobacterial Infections -- Tuberculosis -- Nontuberculous Mycobacteria -- M. abscessus -- Non-M. abscessus Non-M. tuberculosis Mycobacterial Infections -- Fungi -- Endemic Fungal Infections -- Histoplasmosis -- Blastomycosis -- Paracoccidioidomycosis -- Coccidioidomycosis -- Cryptococcosis -- Aspergillus and Other Molds -- Parasitic Infections -- Chagas Disease -- Schistosomiasis -- Strongyloidiasis -- Leishmaniasis -- Malaria -- Toxoplasmosis -- Viral Infections in the Transplant Candidate -- Blood-borne Pathogens -- Endemic Human Herpes Viruses -- Viral Infections with Geographic Associations -- Human Herpesvirus-8 (HHV-8) -- HTLV-1 -- Flaviviruses (Arboviruses) -- West Nile Virus (WNV) -- Zika, Chikungunya, and Dengue Viruses -- Conclusion -- KeyPoints -- References -- 10 Transplant Tourism and the Traveling Transplant Recipient: Infection Mitigation and Treatment Strategies -- Introduction -- Part 1: Transplant Tourism -- Introduction -- Transplant Tourism and Infectious Complications -- Conclusion -- Key Points -- Part 2: The Traveling Transplant Recipient -- Introduction -- Risk of Infection While Abroad -- Viral Infections -- Respiratory Viral Infections -- Influenza -- Measles -- Middle Eastern Respiratory Syndrome -- Gastrointestinal Viral Infections -- Norovirus. ; Hepatitis A -- Hepatitis B -- Hepatitis E -- Polio -- Vector-Borne Viral Infections -- Yellow Fever -- Japanese Encephalitis -- Dengue, Chikungunya, and Zika -- Rabies -- Bacterial Infections -- Salmonella enterica Serovar Typhi -- Vibrio cholerae -- Enterotoxigenic Escherichia coli (ETEC) -- Neisseria meningitidis -- Streptococcus pneumoniae -- Clostridium tetani -- Corynebacterium diphtheriae -- Bordetella pertussis -- Mycobacterial Infections -- Mycobacterium tuberculosis -- Fungal Infections -- Parasitic Infections -- Vector-Borne Parasite Infections -- Plasmodium Species -- Leishmania Species -- Trypanosoma Species -- Babesia Species -- Environmentally Transmitted Parasite Infections -- Strongyloides stercoralis -- Schistosoma Species -- Ingested Parasitic Infections -- Pre-departure Infectious Disease Evaluation and Recommendations -- Vaccine Recommendations -- Risk Reduction of Non-vaccine-Preventable Infections -- Prevention of Food-Borne Illnesses and Diarrhea -- Respiratory Infections -- Insect Protection -- Environmental Exposures -- Blood-Borne Pathogens -- Sexually Transmitted Infections (STI) -- Post-travel Evaluation -- Conclusion -- Key Points -- References -- 11 Preventative Health in Solid Organ Transplant: Safe Living Post-transplant -- Introduction -- Pre-transplant Evaluation -- Vaccination -- Everyday Living Strategies -- Activities of Leisure -- Sexual Health -- Food and Water Safety -- Animal and Insect Precautions -- Travel Advice -- Conclusion -- Key Points -- References -- 12 Vaccination Strategies in Solid Organ and Stem Cell Transplant -- Introduction to Vaccination in Transplant Recipients -- Specific Vaccine Recommendations -- Vaccination Against Influenza -- Vaccination Against Pneumococcal Disease -- Vaccination Against Meningococcal Disease -- Vaccination Against Hepatitis B Virus. ; Vaccination Against Hepatitis A Virus.
• Titolo autorizzato: Emerging Transplant Infections
• ISBN: 3-030-25869-6
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910485605403321
• Lo trovi qui: Univ. Federico II