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Titolo: |
Enzyme defects and immune dysfunction
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Pubblicazione: | Amsterdam ; ; New York, : Excerpta Medica, 1979 |
Descrizione fisica: | 1 online resource (301 pages) : illustrations |
Disciplina: | 616.3/99 |
Soggetto topico: | Immunological deficiency syndromes |
Adenosine deaminase | |
Purines - Metabolism | |
Enzymes | |
Note generali: | "Symposium on Enzyme Defects and Immune Dysfunction, held at the Ciba Foundation, London, 7th-9th November 1978"--Participants page. |
Nota di bibliografia: | Includes bibliographical references and indexes. |
Nota di contenuto: | Enzyme Defects and Immune Dysfunction; Contents; Chairman's introduction; Adenosine deaminase and purine nucleoside phosphorylase deficiency: how they were discovered and what they may mean; Discussion; Buridan's ass: one man's view of the immune system; Discussion; Clinical delineation of adenosine deaminase deficiency; Discussion; Immunological aberrations in purine nucleoside phosphorylase deficiencies; Discussion; Immunodeficiency due to transcobalamin II deficiency; Discussion; General Discussion I Model systems for study of enzyme deficiencies |
Nucleotide metabolism in cultured T cells and in cells of patients deficient in adenosine deaminase and purine nucleoside phosphorylase Discussion; Deoxyribonucleoside toxicity in adenosine deaminase and purine nucleoside phosphorylase deficiency: implications for the development of new immunosuppressive agents; Discussion; Ecto 5'-nucleotidase deficiency in primary hypogammaglobulinaemia; Discussion; General Discussion II The methylation hypothesis of adenosine toxicity; Enzymology of immunodeficiency states; Allosteric regulation of calf thymus ribonucleotide reductase; Discussion | |
Adenosine deaminase: characteristics of the normal and mutant forms of the human enzyme Discussion; Purine nucleoside phosphorylase: the normal enzyme and structural alterations in immunodeficiency disease; Discussion; Purine nucleoside phosphorylase : immunodetection and characterization of the human enzyme; Enzyme replacement and other biochemical approaches to the therapy of adenosine deaminase deficiency; Discussion; An approach to the restoration of T cell function in a purine nucleoside phosphorylase deficient patient; Discussion; Purine metabolism in adenosine deaminase deficiency | |
Final General Discussion Selective treatment of lymphoid malignancy with adenosine deaminase inhibitors Defects in differentiation underlying ADA and PNP deficiency; Search for new enzyme deficiencies; Index of contributors; Subject index | |
Titolo autorizzato: | Enzyme defects and immune dysfunction ![]() |
ISBN: | 1-280-78379-6 |
9786613694188 | |
0-470-72051-4 | |
0-470-71819-6 | |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910144657903321 |
Lo trovi qui: | Univ. Federico II |
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