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Titolo: |
Case studies in modern drug discovery and development / / edited by Xianhai Huang, Robert G. Aslanian
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Pubblicazione: | Hoboken, NJ, : John Wiley & Sons, c2012 |
Edizione: | 1st ed. |
Descrizione fisica: | 1 online resource (451 p.) |
Disciplina: | 615.19 |
Soggetto topico: | Drugs - Design |
Pharmaceutical chemistry | |
Altri autori: |
HuangXianhai
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Note generali: | Bibliographic Level Mode of Issuance: Monograph |
Nota di bibliografia: | Includes bibliographical references and index. |
Nota di contenuto: | Introduction: drug discovery in difficult times / Malcom MacCoss -- Discovery and development of the DPP-4 inhibitor JANUVIA? (Sitagliptin) / Emma R. Parmee ... [et al.] -- Olmesartan medoxiomil, an angiotensin II receptor blocker / Hiroaki Yanagisawa, Hiroyuki Koike, and Shinichiro Miura -- Discovery of heterocyclic phosphonic acids as novel AMP mimics that are potent and selective fructose-1,6-bisphosphatase inhibitors and elicit potent glucose-lowering effects in diabetic animals and human / Qun Dang, and Mark D. Erion -- Setting the paradigm of targeted drugs for the treatment of cancer : Imatinib and Nilotinib therapies for chronic myelogenous leukaemia / Paul W. Manley and Jürg Zimmermann -- Amrubicin, a completely synthetic 9-aminoanthracycline, for extensive-disease small-cell lung cancer / Mitsuharu Hanada -- The discovery of dual IGF-1R and IR inhibitor FQIT for the treatment of cancer / Meizhong Jin, Elizabeth Buck, and Mark J. Mulvihill -- Discovery and development of Montelukast (Singulair?) / Robert N. Young -- Discovery and development of Maraviroc, a CCR5 antagonist for the treatment of HIV Infection / Patrick Dorr, Blanda Stammen, Elna van der Ryst -- Discovery of antimalarial drug Artemisinin and beyond / Ao Zhang, Weiwei Mao, Yu Zhang -- Discovery and process development of MK-4965, a potent non-nucleoside reverse transcriptase inhibitor / Yong-Li Zhong, Thomas J. Tucker, and Jingjun Yin -- Discovery of Boceprevir and Narlaprevir : the first and second generation of HCV NS3 protease inhibitors / Kevin X. Chen, F. George Njoroge -- The discovery of Samsca (Tolvaptan) : the first oral nonpeptide vasopressin receptor antagonist / Kazumi Kondo, Yoshitaka Yamamura -- SILODOSIN (Urief?, Rapaflo?, Thrupas?, Urorec?, SilodixTM) : a selective à1A adrenoceptor antagonist for the treatment of benign prostatic hyperplasia / Masaki Yoshida ... [et al.] -- Raloxifene : a selective estrogen receptor modulator (SERM) / Jeffrey A. Dodge and Henry U. Bryant. |
Titolo autorizzato: | Case studies in modern drug discovery and development ![]() |
ISBN: | 1-280-59100-5 |
9786613620835 | |
1-118-21967-8 | |
1-118-21968-6 | |
1-118-21970-8 | |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910141253903321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |