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Titolo: |
Regulation of Cytokine Gene Expression in Immunity and Diseases / / edited by Xiaojing Ma
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Pubblicazione: | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016 |
Edizione: | 1st ed. 2016. |
Descrizione fisica: | 1 online resource (228 p.) |
Disciplina: | 610 |
Soggetto topico: | Immunology |
Gene expression | |
Cytokines | |
Growth factors | |
Cell biology | |
Gene Expression | |
Cytokines and Growth Factors | |
Cell Biology | |
Persona (resp. second.): | MaXiaojing |
Note generali: | Description based upon print version of record. |
Nota di contenuto: | Regulation of IFN-γ expression -- Regulation of The interleukin-1 family -- Regulation of IL-4 Expression in Immunity and Diseases -- Regulation of IL-6 in immunity and diseases -- Regulation of Interleukin-10 Expression -- Regulation of Interleukin-12 Production in Antigen-Presenting Cells -- Regulation of Interleukin-17 production -- Regulation of interleukin-23 expression in health and disease -- Regulation and immune function of IL-27 -- The immunobiology of Interleukin-35 and its regulation and gene expression. |
Sommario/riassunto: | This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation. . |
Titolo autorizzato: | Regulation of Cytokine Gene Expression in Immunity and Diseases ![]() |
ISBN: | 9789402409215 |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910136605203321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |