Vaccines against virally induced cancers [[electronic resource]]

• Pubblicazione: Chichester ; ; New York, : J. Wiley, 1994
• Descrizione fisica: 1 online resource (293 p.)
• Disciplina: 616.99; 616.992061
• Soggetto topico: Viral carcinogenesis; Viral vaccines; Cancer - Immunotherapy
• Altri autori: FrazerI. H (Ian H.)
• Note generali: "Ciba Foundation"--Cover.; Symposium held at the Ciba Foundation, London, 15-17 March 1994, based on a proposal by Ian Frazer.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: VACC I N ES AGAl NST VIRALLY INDUCED CANCERS; Contents; Participants; Introdu ction; Potential antigenic targets on Epstein - Bar r vir us-associated tumours and the host response; The host response to lesions induced by human papillomavirus; General discussion I; Human T cell lymphotropic virus: necessity for and feasibility of a vaccine; Vaccination against cutaneous and mucosal papillomavirus in cattle; Strategies for studying mouse and human immune responses to human papillomavirus type 16 ; Prospects for T cell immunotherapy of tumours by vaccination with immunodominant and su bdominant peptidesHepatitis B virus infection, the immune response and hepatocellular carcinoma; The role of superantigens in the immunobiology of retroviruses; General discussion I I; Assembly and transport of class I MHC-peptide complexes; Induction and regulation of CD4+ T cell subsets; Propagation of mouse and human T cells with defined antigen specificity and function; Immunity to the HER-2heu oncogenic protein ; Genetic modification of T cell clones to improve the safety and efficacy of adoptive T cell therapyBone marrow-derived cells present MHC class I-restricted tumour antigens in priming of antiturnour immune responses; Evasion of host immune responses by tumours and viruses; Final dscussion; Index of contributors; Subject index
• Sommario/riassunto: An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tumors and discuss the means by which they can be improved.
• Titolo autorizzato: Vaccines against virally induced cancers
• ISBN: 1-282-13792-1; 9786612137921; 0-470-51467-1; 0-470-51468-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910840899903321
• Lo trovi qui: Univ. Federico II
• Serie: Ciba Foundation symposium ; ; 187.