Bioisosteres in medicinal chemistry / / edited by Nathan Brown
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| Titolo: |
Bioisosteres in medicinal chemistry / / edited by Nathan Brown
|
| Pubblicazione: | Weinheim, Germany, : Wiley-VCH, 2012 |
| Edizione: | 1st ed. |
| Descrizione fisica: | 1 online resource (258 p.) |
| Disciplina: | 615.19 |
| Soggetto topico: | Pharmaceutical chemistry |
| Altri autori: |
BrownNathan
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references and index. |
| Nota di contenuto: | pt. 1. Principles -- pt. 2. Data -- pt. 3. Methods -- pt. 4. Applications. |
| Sommario/riassunto: | Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered,while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third partcovers the four |
| Titolo autorizzato: | Bioisosteres in medicinal chemistry |
| ISBN: | 3-527-65432-1 |
| 1-280-77853-9 | |
| 9786613688927 | |
| 3-527-65430-5 | |
| 3-527-65433-X | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910816930203321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Methods and principles in medicinal chemistry ; ; v. 54.