The cardiovascular system

• Pubblicazione: Cold Spring Harbor, N.Y., : Cold Spring Harbor Laboratory Press, c2002
• Descrizione fisica: 1 online resource (xxi, 566 pages) : illustrations (some color), portraits
• Soggetto topico: Cardiovascular system; Cardiovascular system - Genetic aspects; Cardiovascular receptors
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: Intro -- Symposium Participants -- Foreword -- Contents -- Cardiogenesis in the Drosophila Model: Control Mechanisms during Early Induction and Diversification of Cardiac Progenitors -- Regulation of Cardiac Muscle Differentiation in Xenopus laevis Embryos -- Genetic Regulation of Cardiac Patterning in Zebrafish -- Zebrafish Hearts and Minds: Nodal Signaling in Cardiac and Neural Left- Right Asymmetry -- Cardiac Left-Right Development: Are the Early Steps Conserved? -- Erythropoietin and Retinoic Acid Signaling in the Epicardium Is Required for Cardiac Myocyte Proliferation -- Endocardial Cushion Formation in Zebrafish -- Neural Crest Migration and Mouse Models of Congenital Heart Disease -- Hey bHLH Factors in Cardiovascular Development -- Molecular Mechanisms of Chamber-specific Myocardial Gene Expression: Transgenic Analysis of the ANF Promoter -- Pitx Genes during Cardiovascular Development -- Pitx2 and Cardiac Development: A Molecular Link between Left/ Right Signaling and Congenital Heart Disease -- Regulation of Cardiac Growth and Development by SRF and Its Cofactors -- Homeodomain Factor Nkx2-5 in Heart Development and Disease -- Causes of Clinical Diversity in Human TBX5 Mutations -- Molecular Mechanisms of Ventricular Hypoplasia -- Hypoxia, HIFs, and Cardiovascular Development -- Quiescent Hypervascularity Mediated by Gain of HIF- 1a Function -- The Diverse Roles of Integrins and Their Ligands in Angiogenesis -- Arteries, Veins, Notch, and VEGF -- Cell Cycle Signaling and Cardiovascular Disease -- Selective Functions of Angiopoietins and Vascular Endothelial Growth Factor on Blood Vessels: The Concept of Ï Vascular DomainÓ -- Survival Mechanisms of VEGF and PlGF during Microvascular Remodeling -- Molecular Mechanisms of Lymphangiogenesis -- Protease-activated Receptors in the Cardiovascular System. ; Migration of Monocytes/Macrophages In Vitro and In Vivo Is Accompanied by MMP12- dependent Tunnel Formation and by Neovascularization -- The Role of EG-VEGF in the Regulation of Angiogenesis in Endocrine Glands -- Profiling the Molecular Diversity of Blood Vessels -- VEGF-A Induces Angiogenesis, Arteriogenesis, Lymphangiogenesis, and Vascular Malformations -- Angiogenesis and Lymphangiogenesis in Tumors: Insights from Intravital Microscopy -- A Genetic Approach to Understanding Tumor Angiogenesis -- Discovery of Type IV Collagen Non-collagenous Domains as Novel Integrin Ligands and Endogenous Inhibitors of Angiogenesis -- Complementary and Coordinated Roles of the VEGFs and Angiopoietins during Normal and Pathologic Vascular Formation -- Involvement of G Proteins in Vascular Permeability Factor/ Vascular Endothelial Growth Factor Signaling -- Targeted Delivery of Mutant Raf Kinase to Neovessels Causes Tumor Regression -- Combining Antiangiogenic Agents with Metronomic Chemotherapy Enhances Efficacy against Late- stage Pancreatic Islet Carcinomas in Mice -- Zebrafish: The Complete Cardiovascular Compendium -- Consomic Rats for the Identification of Genes and Pathways Underlying Cardiovascular Disease -- A Mouse Model of Congenital Heart Disease: Cardiac Arrhythmias and Atrial Septal Defect Caused by Haploinsufficiency of the Cardiac Transcription Factor Csx/ Nkx2.5 -- Genetic Dissection of the DiGeorge Syndrome Phenotype -- A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine- induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel -- Calcium-dependent Gene Regulation in Myocyte Hypertrophy and Remodeling -- A Gradient of Myosin Regulatory Light-chain Phosphorylation across the Ventricular Wall Supports Cardiac Torsion. ; Molecular and Functional Maturation of the Murine Cardiac Conduction System -- The Yin/Yang of Innate Stress Responses in the Heart -- Regulatory Networks Controlling Mitochondrial Energy Production in the Developing, Hypertrophied, and Diabetic Heart -- Molecular Epidemiology of Hypertrophic Cardiomyopathy -- The Sarcoglycan Complex in Striated and Vascular Smooth Muscle -- The MLP Family of Cytoskeletal Z Disc Proteins and Dilated Cardiomyopathy: A Stress Pathway Model for Heart Failure Progression -- From Sarcomeric Mutations to Heart Disease: Understanding Familial Hypertrophic Cardiomyopathy -- Vascular Endothelium in Tissue Remodeling: Implications for Heart Failure -- Using a Gene-switch Transgenic Approach to Dissect Distinct Roles of MAP Kinases in Heart Failure -- G-Protein-coupled Receptor Function in Heart Failure -- Salt and Blood Pressure: New Insight from Human Genetic Studies -- Gene-targeting Studies of the Renin-Angiotensin System: Mechanisms of Hypertension and Cardiovascular Disease -- Modulation of Endothelial NO Production by High- density Lipoprotein -- Plaque Angiogenesis: Its Functions and Regulation -- Extracellular Superoxide Dismutase, Uric Acid, and Atherosclerosis -- SREBPs: Transcriptional Mediators of Lipid Homeostasis -- Genetic Defenses against Hypercholesterolemia -- Insulin-like Growth Factor Isoforms in Skeletal Muscle Aging, Regeneration, and Disease -- Cellular Therapies for Myocardial Infarct Repair -- Gene Therapy for Cardiac Arrhythmias -- Myocardial Disease in Failing Hearts: Defective Excitation-Contraction Coupling -- The Coming of Age of Cardiovascular Science -- Author Index -- Subject Index.
• Sommario/riassunto: This latest volume in a prestigious book series presents a remarkable survey of current progress in these efforts, through the contributions of over fifty of the world's leading investigators. Sections are devoted to angiogenesis, cardiogenesis, homeostasis, development, vascular biology, and cardiovascular repair and therapy. The book is an essential source of ideas, discoveries, and references for clinical scientists and physicians interested in basic cardiac biology, hypertension, atherosclerosis, coronary artery disease, and heart failure.
• Titolo autorizzato: The Cardiovascular System
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910809166103321
• Lo trovi qui: Univ. Federico II
• Serie: Cold Spring Harbor symposia on quantitative biology (Series) ; ; v. 67.