Cord blood stem cells medicine / / edited by Catherine Stavropoulos-Giokas, Dominique Charron, Cristina Navarrete

• Pubblicazione: London : , : Academic Press, , 2015; ©2015
• Descrizione fisica: 1 online resource (399 p.)
• Disciplina: 616.02774
• Soggetto topico: Stem cells - Therapeutic use; Umbilical cord; Regenerative medicine
• Persona (resp. second.): Stavropoulos-GiokasCatherine; CharronD (Dominique); NavarreteCristina
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: FrontCover; Cord Blood StemCells Medicine; Copyright; Contents; List of Contributors; Foreword; TWENTY-FIVE YEARS OF CORD BLOOD TRANSPLANT; Section I -Introduction; Chapter 1 - Introduction to Cord Blood Stem Cells; Section II -Cord Blood Cells Biology; Chapter 2 - Cord Blood Content; 1. BIOLOGICAL BACKGROUND OF CORD BLOOD CELLS-DEVELOPMENT OF HEMATOPOIETIC AND NONHEMATOPOIETIC CELLS; 2. ENDOTHELIAL CELLS IN CB; 3. STROMAL CELLS IN CB AND CORD TISSUE AS COMPARED TO BM; 4. ISOLATION, EXPANSION, AND CHARACTERIZATION OF CB-DERIVED ADHERENT CELLS FROM CB ; 5. GENERATION OF CELL CLONES AND CLONAL POPULATIONS6. USSC AND CB MSC; 7. GENERATION OF ADHERENT CELLS FROM THE WHARTON'S JELLY (CORD); 8. GENE EXPRESSION PROFILES; 9. CORRELATION OF HOX-GENE EXPRESSION AND REGENERATIVE POTENTIAL; 10. BONE AND CARTILAGE FORMING POTENTIAL OF CORD BLOOD STROMAL CELLS; 11. WHY DO WE HAVE THESE PROGENITORS OR ELUSIVE CELLS IN CB?; 12. USSC AND MSC FROM CB SUPPORT HEMATOPOIETIC CELLS; 13. LIVER REGENERATION AND POTENTIAL OF CB-DERIVED STEM CELLS TO UNDERGO HEPATIC DIFFERENTIATION; 14. CARDIAL REGENERATION IN VIVO ; 15. IN VITRO DIFFERENTIATION POTENTIAL TOWARD CARDIOMYOCYTES16. CB SUBPOPULATIONS FOR NEURONAL REGENERATION; 17. REPROGRAMMED SUBPOPULATIONS FROM CB; 18. CONCLUSION; LIST OF ACRONYMS AND ABBREVIATIONS; REFERENCES; Chapter 3 - Cord Blood Hematopoiesis: The Road to Transplantation; 1. USE OF PLACENTAL CORD BLOOD AS A SOURCE FOR HEMATOPOIETIC STEM/PROGENITOR CELLS TRANSPLANTATION: A HISTORICAL PERSPECTIVE; 2. CHARACTERIZATION OF PCB HSPCS; 3. STRATEGIES TO OVERCOME CURRENT LIMITATIONS IN PCB TRANSPLANTATION; 4. INCREASING THE HSPCS OF THE GRAFT; 5. IMPROVING THE LODGING CAPACITY OF THE PCB GRAFT ; 6. IMPROVING THE STEM CELL RECEPTIVITY OR IMMUNOLOGICAL STATUS OF THE HOST7. ADDITIONAL CLINICAL USES OF CORD BLOOD UNDER INVESTIGATION; 8. CONCLUDING REMARKS; REFERENCES; Chapter 4 - Immunobiology of Cord Blood Cells; 1. INTRODUCTION; 2. IMMUNE PROPERTIES OF CORD BLOOD CELLS; 3. IMMUNE RECONSTITUTION AFTER CBT; 4. GENERATION OF IMMUNE COMPETENT CELLS FROM CORD BLOOD; 5. CONCLUSION; LIST OF ABBREVIATIONS; REFERENCES; Chapter 5 - Cord and Cord Blood-derived Endothelial Cells; 1. INTRODUCTION; 2. THE HUMAN ENDOTHELIAL COLONY-FORMING CELL HIERARCHY ; 3. DIFFERENCES BETWEEN HUMAN UMBILICAL CORD BLOOD ECFCS AND THOSE SOURCED FROM ADULT PERIPHERAL BLOOD, UMBILICAL CORD, AND PLACE...4. OBSTETRIC FACTORS AND ECFC CONTENT IN UMBILICAL CORD BLOOD AT TERM; 5. ECFC CONTENT AND FUNCTION IN UMBILICAL CORD BLOOD BASED ON GESTATIONAL AGE; 6. THE DIABETIC ENVIRONMENT AFFECTS UMBILICAL CORD BLOOD ECFCS; 7. PROCESSING AND CRYOPRESERVATION AFFECT ECFC NUMBERS IN UMBILICAL CORD BLOOD; 8. THE PHENOTYPIC IDENTITY OF ECFCS; 9. THE USE OF UMBILICAL CORD BLOOD OR PLACENTAL ECFCS AS A CELLULAR PRODUCT IN REGENERATIVE MEDICINE; 10. CONCLUSIONS ; LIST OF ACRONYMS AND ABBREVIATIONS
• Sommario/riassunto: Cord Blood Stem Cells and Regenerative Medicine discusses the current applications for cord blood stem cells and techniques for banking cord blood. Cord blood, blood from the umbilical cord and placenta of an infant, represents an alternate source of stem cells that can be used to treat a myriad of disorders. Cord blood stem cells are being used more frequently and studied more seriously, as evidenced by the explosion of scientific literature on the topic. Currently, clinical and pre-clinical trials are being done in the field, treating conditions as severe as heart failure. Coupled with re
• Titolo autorizzato: Cord blood stem cells medicine
• ISBN: 0-12-407836-2
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910788068303321
• Lo trovi qui: Univ. Federico II