Cerebrovascular disease : 22nd Princeton Conference / / edited by Pak H. Chan [[electronic resource]]

• Pubblicazione: Cambridge : , : Cambridge University Press, , 2002
• Descrizione fisica: 1 online resource (xxii, 461 pages) : digital, PDF file(s)
• Disciplina: 616.1
• Soggetto topico: Cerebrovascular disease - Pathophysiology; Cerebrovascular disease - Treatment
• Persona (resp. second.): ChanPak H.
• Note generali: Title from publisher's bibliographic system (viewed on 05 Oct 2015).
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover; Half-title; Title; Copyright; Contents; Contributors; Preface; Acknowledgments; Major contributors; 1 Zinc toxicity in the ischemic brain; 2 Central nervous system ischemia: diversity among the caspases; 3 Peroxynitrite and injury to the vasculature and central nervous system in stroke and neurodegeneration; 4 Interaction between inducible nitric oxide and cyclooxygenase-2 in ischemic brain injury; 5 Mechanisms of ischemic tolerance; 6 Clinically tolerated NMDA receptor antagonists and newly cloned NMDA receptor subunits that mimic them ; 7 Cell death programs in neural development and disease 8 Apoptotic gene expression in brain ischemia and ischemic tolerance; 9 Cellular mechanisms of white matter ischemia: what can we learn from culture models?; 10 Astrocytes in ischemic stroke; 11 Aquaporin-4 water channels and brain edema; 12 Neuroprotection with tetracyclines in brain ischemia models; 13 Spreading depression: a teleological means for self-protection from brain ischemia; 14 The role of matrix metalloproteinases and urokinase in blood-brain barrier damage with thrombolysis ; 15 Does brain nitric oxide generation influence tissue oxygenation after severe human subarachnoid hemorrhage?16 Tissue plasminogen activator and hemorrhagic brain injury; 17 Dynamics of infarct evolution after permanent and transient focal brain ischemia in mice; 18 Inflammation and stroke: benefits or harm?; 19 TNF-alpha and ceramide are involved in the mediation of neuronal tolerance to brain ischemia; 20 Sites and mechanisms of IL-1 action in ischemic and excitotoxic brain damage; 21 Protease generation, inflammation and cerebral microvascular activation ; 22 Adenoviral vectors for gene therapy in stroke 23 Gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury; 24 Vasomotor effects of nitric oxide, superoxide dismutases and calcitonin gene-related peptide; 25 Transplantation of neural stem cells: cellular and gene therapy in pediatric hypoxic-ischemic brain injury; 26 Neural plasticity after cerebral ischemia; 27 Environmental effects on recovery after stroke; 28 Magnetic resonance imaging in stroke trials ; 29 Disappearing deficits and disappearing lesions: diffusion/perfusion MRI in transient ischemic attack and intra-arterial...30 Diffusion and perfusion magnetic resonance imaging in the evaluation of acute ischemic stroke; 31 Early recanalization in acute ischemic stroke saves tissue at risk defined by stroke magnetic resonance imaging; 32 Vascular factors in Alzheimer's disease; 33 Beyond neuroprotection: the protection of axons and oligodendrocytes in cerebral ischemia; 34 Combining neuroprotection with thrombolysis: how to translate laboratory success to our clinical trials ; 35 Prospects for improved neuroprotection trials in stroke
• Sommario/riassunto: Prevention, diagnosis and treatment are the watchwords in stroke research, for basic neuroscientists and clinicians alike. This 2002 book, from the 22nd Princeton Conference on Cerebrovascular Disease, contains contributions from outstanding investigators on numerous topics in stroke research. The contents cover the status and future directions of stroke pathophysiology, diagnosis and treatment, with special emphasis on the molecular and cellular mechanisms of ischaemic cell death and repair, and clinical issues including imaging, risk factors and therapeutic strategies in stroke. Available in both print and online formats, this survey of the basic and clinical science of stroke is an essential resource for all involved in advancing knowledge of cerebrovascular disease.
• Titolo autorizzato: Cerebrovascular disease
• ISBN: 1-107-13068-9; 1-280-16053-5; 9786610160532; 0-511-11947-X; 1-139-14716-1; 0-511-06350-4; 0-511-05717-2; 0-511-30825-6; 0-511-54491-X; 0-511-07196-5
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910783115803321
• Lo trovi qui: Univ. Federico II