Studies on Respiratory Disorders / / edited by Nirmal K. Ganguly, Surinder K. Jindal, Shyam Biswal, Peter J. Barnes, Ruby Pawankar

• Pubblicazione: New York, NY : , : Springer New York : , : Imprint : Humana, , 2014
• Edizione: 1st ed. 2014.
• Descrizione fisica: 1 online resource (396 p.)
• Disciplina: 616.2
• Soggetto topico: Oxidative stress; Cell biology; Respiratory organs—Diseases; Oxidative Stress; Cell Biology; Pneumology/Respiratory System
• Persona (resp. second.): GangulyNirmal K; JindalSurinder K; BiswalShyam; BarnesPeter J; PawankarRuby
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Introduction to oxidative stress and anti-oxidant therapy -- Role of reactive oxygen and nitrogen species in respiratory diseases: general considerations -- Role of exhaled biomarkers volatiles and exhaled breath condensate -- Pulmonary infections and oxidative injury -- Role of reactive oxygen species in causing acute lung injury -- Free radicals in pulmonary tuberculosis -- Oxidative injury caused by smoking and air-pollution -- Oxidative stress in chronic obstructive pulmonary disease -- Oxidative stress in asthma and allergic disease -- Oxygen free radicals in pulmonary hypertension -- Pulmonary fibrosis and oxidative stress -- Oxidant injury in sarcoidosis and other granulomatous disorders -- Oxidative stress in lung cancer -- Pulmonary toxicity from drugs, heavy metals and other poisonings – oxidant injury and role of anti-oxidants -- Oxidative stress and respiratory muscle dysfunction -- The critical role of Nrf2 -- Development of novel antioxidants -- Asbestosis.
• Sommario/riassunto: Studies on Respiratory Disorders considers the whole panorama of oxidative damage in different respiratory disorders for the review of clinician and laboratory investigators and makes diverse information available in a single volume. This volume provides a comprehensive review of numerous studies on the role of oxygen and nitrogen species in lung diseases; it also discusses the potential role of anti-oxidants in their treatment. The contents are organized into three sections along fairly broad classifications: I. General introductory chapters on oxidant stress; general considerations related to reactive oxygen and nitrogen species; the role of exhaled breath condensate and other volatile compounds as exhaled biomarkers of inflammation; II. Oxidative stress in different groups of respiratory disorders such as pulmonary infections (viral, bacterial and tuberculosis); airway diseases such as chronic obstructive pulmonary diseases, air pollution, allergies and asthma; miscellaneous lung diseases (e.g., interstitial diseases, sarcoidosis, asbestosis, respiratory muscle dysfunction, pulmonary hypertension and cancer); and III., Anti-oxidant drugs. These final chapters on anti-oxidant drugs including the mimics (such as traditional herbs) provide a critical review of the available information on their success and failure. Studies on Respiratory Disorders is an important addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series and is essential reading for those treating or researching treatment for respiratory disorders.
• Titolo autorizzato: Studies on Respiratory Disorders
• ISBN: 1-4939-0497-3
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298338003321
• Lo trovi qui: Univ. Federico II
• Serie: Oxidative Stress in Applied Basic Research and Clinical Practice, . 2197-7224