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[null,"1.","Record Nr.",null,"UNINA9910557222003321"]
[null,null,"Autore",null,"Hattori Yuichi"]
[null,null,"Titolo",null,"G Protein-Coupled Receptor Kinases (GRKs) and Beta-Arrestins: New Insights into Disease Regulators"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2020"]
[null,null,"Descrizione fisica",null,"1 online resource (182 p.)"]
[null,null,"Soggetti",null,"Pharmacology"]
[{"$nulls":4},"Science: general issues"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","G protein-coupled receptor kinases (GRKs) and arrestins were initially identified as a pivotal player in the process of desensitization of agonist-activated G protein-coupled receptors (GPCRs). However, growing evidence suggests GRKs and arrestins fulfill a vital role in regulating a variety of cellular proteins involved in signal transduction independently of GPCRs. Thus, GRKs and arrestins can interact with non-GPCRs. GRKs and arrestins may directly affect functioning of non-GPCRs or indirectly regulate non-GPCR signaling. In addition, emerging evidence supports that changes in function and/or expression of GRKs and arrestins may be important in cardiovascular, inflammatory, metabolic, or cancer pathologies. A better understanding of the pathological roles of GRKs and arrestins would provide a basis for new therapeutic targets in different human diseases."]
[null,"2.","Record Nr.",null,"UNISANNIOMIL0178232"]
[null,null,"Autore",null,"Italia"]
[null,null,"Titolo",null,"2 / [a cura di] Vittorio Italia"]
[null,null,"Pubbl/distr/stampa",null,"Milano, : Giuffrè, stampa 1990"]
[null,null,"ISBN",null,"8814025266"]
[null,null,"Descrizione fisica",null,"P. 2684-5188 ; 20 cm"]
[null,null,"Disciplina",null,"342.06"]
[null,null,"Collocazione",null,"POZZO LIB.ECON MON                7660"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]