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[null,"1.","Record Nr.",null,"UNISALENTO991003285669707536"]
[null,null,"Autore",null,"De Lisio, Pasquale Alberto"]
[null,null,"Titolo",null,"Letteratura fra centro e periferia : studi in memoria di Pasquale Alberto De Lisio / a cura di Gioacchino Paparelli e Sebastiano Martelli"]
[null,null,"Pubbl/distr/stampa",null,"Napoli : c 1987"]
[null,null,"Descrizione fisica",null,"1291 p. ; 24 cm"]
[null,null,"Collana",null,"Pubblicazioni dell'Università degli studi di Salerno. Sezione atti, convegni, miscellanee ; 15"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910299705703321"]
[null,null,"Autore",null,"Kashyap Amita"]
[null,null,"Titolo",null,"Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene / / by Amita Kashyap, D. Bujamma, Naresh Babu M"]
[null,null,"Pubbl/distr/stampa",null,"Singapore : , : Springer Singapore : , : Imprint : Springer, , 2015"]
[null,null,"ISBN",null,"981-4585-08-4"]
[null,null,"Edizione",null,"[1st ed. 2015.]"]
[null,null,"Descrizione fisica",null,"1 online resource (79 p.)"]
[null,null,"Collana",null,"SpringerBriefs in Forensic and Medical Bioinformatics, , 2196-8845"]
[null,null,"Disciplina",null,"006.3"]
[{"$nulls":4},"502.85"]
[{"$nulls":4},"519"]
[{"$nulls":4},"570285"]
[null,null,"Soggetti",null,"Computational intelligence"]
[{"$nulls":4},"Bioinformatics"]
[{"$nulls":4},"Cancer - Research"]
[{"$nulls":4},"Biomedical engineering"]
[{"$nulls":4},"Medical informatics"]
[{"$nulls":4},"Applied mathematics"]
[{"$nulls":4},"Engineering mathematics"]
[{"$nulls":4},"Computational Intelligence"]
[{"$nulls":4},"Computational Biology/Bioinformatics"]
[{"$nulls":4},"Cancer Research"]
[{"$nulls":4},"Biomedical Engineering and Bioengineering"]
[{"$nulls":4},"Health Informatics"]
[{"$nulls":4},"Mathematical and Computational Engineering"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Introduction -- Review of Literature -- Materials and Methods (Tools and Databases) -- Flowchart -- Conclusion.-References."]
[null,null,null,"Sommario/riassunto","Cancer is initiated by activation of oncogenes or inactivation of tumor suppressor genes. Mutations in the K-ras proto-oncogene are responsible for 10–30% of adenocarcinomas. Clinical Findings point to a wide variety of other cancers contributing to lung cancer incidence. Such a scenario makes identification of lung cancer difficult and thus identifying its mechanisms can contribute to the society. Identifying unique conserved patterns common to contributing proto-oncogenes "]
[{"$nulls":4},"may further be a boon to Pharmacogenomics and pharmacoinformatics. This calls for ab initio/de novo drug discovery that in turn will require a comprehensive in silico approach of Sequence, Domain, Phylogenetic and Structural analysis of the receptors, ligand screening and optimization and detailed Docking studies. This brief involves extensive role of the RAS subfamily that includes a set of proteins, which cause an over expression of cancer-causing genes like M-ras and initiate tumour formation in lungs. SNP Studies and Structure based drug discovery will also be undertaken."]