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[null,"1.","Record Nr.",null,"UNISALENTO991002954629707536"]
[null,null,"Autore",null,"Rouvière, François"]
[null,null,"Titolo",null,"Symmetric spaces and the Kashiwara-Vergne method [e-book] / François Rouvière"]
[null,null,"Pubbl/distr/stampa",null,"Cham [Switzerland] : Springer, 2014"]
[null,null,"ISBN",null,"9783319097732"]
[null,null,"Descrizione fisica",null,"1 online resource (xxi, 196 pages)"]
[null,null,"Collana",null,"Lecture Notes in Mathematics, 1617-9692 ; 2115"]
[null,null,"Classificazione",null,"AMS 22E30"]
[{"$nulls":4},"AMS 17B01"]
[{"$nulls":4},"AMS  22E60"]
[{"$nulls":4},"AMS 53C35"]
[{"$nulls":4},"LC QA387.R685"]
[null,null,"Disciplina",null,"512.482"]
[null,null,"Soggetti",null,"Lie groups"]
[{"$nulls":4},"Symmetric spaces"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index"]
[null,null,"Nota di contenuto",null,"Introduction ; Notation ; The Kashiwara-Vergne method for Lie groups ; Convolution on homogeneous spaces ; The role of e-functions ; e-functions and the Campbell Hausdorff formula ; Bibliography"]
[null,null,null,"Sommario/riassunto","Gathering and updating results scattered in journal articles over thirty years, this self-contained monograph gives a comprehensive introduction to the subject. Its goal is to: - motivate and explain the method for general Lie groups, reducing the proof of deep results in invariant analysis to the verification of two formal Lie bracket identities related to the Campbell-Hausdorff formula (the \"Kashiwara-Vergne conjecture\"); - give a detailed proof of the conjecture for quadratic and solvable Lie algebras, which is relatively elementary; - extend the method to symmetric spaces; here an obstruction appears, embodied in a single remarkable object called an \"e-function\"; - explain the role of this function in invariant analysis on symmetric spaces, its relation to invariant differential operators, mean value operators and spherical functions; - give an explicit e-function for rank one spaces (the hyperbolic spaces); - construct an e-function for general symmetric spaces, in the spirit of Kashiwara and Vergne's original work for Lie groups. The book includes a complete rewriting of several articles by the author, updated and improved following Alekseev, Meinrenken and Torossian's recent proofs of the conjecture. The chapters are largely "]
[{"$nulls":4},"independent of each other. Some open problems are suggested to encourage future research. It is aimed at graduate students and researchers with a basic knowledge of Lie theory"]
[null,"2.","Record Nr.",null,"UNINA9910619465503321"]
[null,null,"Autore",null,"Allison Simon J"]
[null,null,"Titolo",null,"Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action"]
[null,null,"Pubbl/distr/stampa",null,"MDPI - Multidisciplinary Digital Publishing Institute, 2022"]
[null,null,"ISBN",null,"3-0365-5222-7"]
[null,null,"Descrizione fisica",null,"1 online resource (206 p.)"]
[null,null,"Soggetti",null,"History of engineering & technology"]
[{"$nulls":4},"Technology: general issues"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Patient outcomes remain poor for many cancers despite improvements in treatments and new molecular-targeted biomedicines for certain cancer types or subtypes. Dose-limiting toxicity, a narrow therapeutic index, and the development of resistance to traditional anti-cancer agents are well-established. It is apparent that inherent and acquired drug resistance are major challenges with molecular-targeted agents and that on- as well as off-target side effects can still occur. Other issues include drug metabolism by the body and safely supplying a sufficient amount of active drug to the tumor cells. There is a clear and urgent need for new molecular targets and drugs that specifically target cancer cells in different ways to existing approved drugs. This book, through a collection of eight research articles and two review articles from the Biomedicines themed Special Issue 'Novel Anti-Cancer Agents and Cellular Targets and Their Mechanism(s) of Action', provides a snapshot of some of the diverse and exciting research approaches being taken by the cancer research community in trying to address some of these therapeutic challenges."]