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[null,"1.","Record Nr.",null,"UNISALENTO991002707429707536"]
[null,null,"Autore",null,"Mölk, Ulrich"]
[null,null,"Titolo",null,"Das älteste französische kreuzlied und der erfurter Codex Amplonianus 8o 32 / von Ulrich Mölk"]
[null,null,"Pubbl/distr/stampa",null,"Göttingen : Vandenhoeck & Ruprecht, 2001"]
[null,null,"Descrizione fisica",null,"36 p. ; 25 cm"]
[null,null,"Collana",null,"Nachrichten der Akademie der wissenschaften. Philologisch-historische klasse ; Jahrg. 2001/10"]
[null,null,"Disciplina",null,"780.902"]
[null,null,"Soggetti",null,"Musica vocale - Francia - Sec. 6.-15. - Manoscritti"]
[{"$nulls":4},"Manoscritti - Francia - Cataloghi"]
[null,null,"Lingua di pubblicazione",null,"Tedesco"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNINA9910830216303321"]
[null,null,"Titolo",null,"Transporters as drug carriers [[electronic resource] ] : structure, function, substrates / / edited by Gerhard Ecker and Peter Chiba"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim, : Wiley-VCH, c2009"]
[null,null,"ISBN",null,"1-282-30246-9"]
[{"$nulls":4},"9786612302466"]
[{"$nulls":4},"3-527-62742-1"]
[{"$nulls":4},"3-527-62743-X"]
[null,null,"Descrizione fisica",null,"1 online resource (451 p.)"]
[null,null,"Collana",null,"Methods and principles in medicinal chemistry ; ; v. 44"]
[null,null,"Disciplina",null,"615.19"]
[null,null,"Soggetti",null,"Drug carriers (Pharmacy)"]
[{"$nulls":4},"Drugs - Physiological transport"]
[{"$nulls":4},"Drug resistance"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Transporters as Drug Carriers: Structure, Function, Substrates; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Human Transporter Families - Structure, Function, Physiology; 1 The ABC Transporters: Structural Insights into Drug Transport; 1.1 ABC Proteins - Structure and Function; 1.1.1 ABC Proteins; 1.1.2 Predicted Topology of ABC Proteins; 1.1.3 Nucleotide Binding Domains; 1.1.3.1 Conserved Motifs of NBDs; 1.1.4 Transmembrane Domains; 1.1.5 Mechanisms of Transport; 1.1.6 Energy for Translocation; 1.1.7 Coupling of ATP Hydrolysis to Transport"]
[{"$nulls":4},"1.2 Structures of ABC Transporters1.2.1 Tertiary Structure; 1.2.2 Quaternary Structure of ABC Proteins; 1.3 Multidrug Resistance and ABC Transporters; 1.3.1 P-Glycoprotein; 1.3.1.1 Historical Background; 1.3.1.2 The Role of P-gp in Drug Resistance; 1.3.1.3 Tissue Distribution and Physiological Roles; 1.3.2 Conformational Changes in the Mechanism of P-gp; 1.3.3 Comparison of Sav1866 and P-gp Structures; 1.3.4 Drug Binding Sites in P-Glycoprotein; 1.3.5 Structural Interpretation of Drug Binding; 1.3.6 Inhibitors of P-gp"]
[{"$nulls":4},"1.3.7 What Properties Are Shared by Drugs that Interact with P-Glycoprotein?1.3.8 Postscript: Further X-Ray Crystallographic Studies and a Structure for the Nucleotide-Free State of P-Glycoprotein; 1.4 Summary; References; 2 Biochemistry, Physiology, and Pharmacology of "]
[{"$nulls":4},"Nucleoside and Nucleobase Transporters; 2.1 Nucleoside and Nucleobase Transporters; 2.1.1 Equilibrative Nucleoside Transporters; 2.1.2 Concentrative Nucleoside Transporters; 2.2 ENT and CNT Tissue Distribution, Regulation, and Physiological Roles; 2.2.1 ENT Tissue Distribution and Regulation"]
[{"$nulls":4},"2.2.2 CNT Tissue Distribution and Regulation2.2.2.1 CNTs in Absorptive Epithelia; 2.2.2.2 CNTs in Liver Parenchymal Cells; 2.2.2.3 CNTs in Immune System Cells; 2.2.2.4 CNTs in CNS; 2.2.2.5 CNTs in Other Specialized Tissues; 2.2.3 NTs as \"\"Transceptors\"\"; 2.3 Nucleoside- and Nucleobase-Derived Drug Transport into Cells; 2.3.1 Transport of Anticancer Drugs; 2.3.2 Transport of Antiviral Drugs; 2.4 Drug Transport and Responsiveness to Treatment; 2.4.1 Analysis of the Role of NTs in Sensitivity to Nucleoside Anticancer Drugs in Cultured Cell Models"]
[{"$nulls":4},"2.4.2 Studies Linking NT Function to Drug Sensitivity and Clinical Outcome in Cancer Patients2.5 Future Perspectives; References; 3 Organic Anion Transporting Polypeptides (Oatps/OATPs); 3.1 Introduction; 3.2 Nomenclature and Classification; 3.3 Tissue Distribution, Structure, and Functions; 3.4 Substrate Spectrum; 3.5 Members of the Rodent Oatp Family; 3.5.1 Oatp1a1; 3.5.2 Oatp1a3-v1/v2; 3.5.3 Oatp1a4; 3.5.4 Oatp1a5; 3.5.5 Oatp1a6; 3.5.6 Oatp1b2; 3.5.7 Oatp1c1; 3.5.8 Oatp2a1; 3.5.9 Oatp2b1; 3.5.10 Oatp3a1; 3.5.11 Oatp4a1; 3.5.12 Oatp4c1; 3.5.13 Oatp6b1/Oatp6c1; 3.5.14 PGT-2"]
[{"$nulls":4},"3.5.15 TST-1 and TST-2"]
[null,null,null,"Sommario/riassunto","This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion.As a result, this key resource lays the foundations for understanding and investi"]