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[null,"1.","Record Nr.",null,"UNINA9910819845003321"]
[null,null,"Titolo",null,"Aggregation of therapeutic proteins / / edited by Wei Wang, Christopher J. Roberts"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, NJ, : Wiley, c2010"]
[null,null,"ISBN",null,"9786612707988"]
[{"$nulls":4},"9781118043585"]
[{"$nulls":4},"1118043588"]
[{"$nulls":4},"9781282707986"]
[{"$nulls":4},"1282707981"]
[{"$nulls":4},"9780470769829"]
[{"$nulls":4},"0470769823"]
[{"$nulls":4},"9780470769812"]
[{"$nulls":4},"0470769815"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (514 p.)"]
[null,null,"Disciplina",null,"615.5/8"]
[null,null,"Soggetti",null,"Protein drugs"]
[{"$nulls":4},"Aggregation (Chemistry)"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references  and index."]
[null,null,"Nota di contenuto",null,"AGGREGATION OF THERAPEUTIC PROTEINS; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: Fundamental Structures and Behaviors of Proteins; CHAPTER 2: Protein Aggregation Pathways, Kinetics, and Thermodynamics; CHAPTER 3: Identification and Impact of Aggregation-Prone Regions in Proteins and Therapeutic Monoclonal Antibodies; CHAPTER 4: External Factors Affecting Protein Aggregation; CHAPTER 5: Experimental Detection and Characterization of Protein Aggregates; CHAPTER 6: Approaches to Control Protein Aggregation during Bulk Production"]
[{"$nulls":4},"CHAPTER 7: Protein Aggregation and Particle Formation: Effects of Formulation, Interfaces, and Drug Product Manufacturing OperationsCHAPTER 8: Approaches to Managing Protein Aggregation in Product Development; CHAPTER 9: Case Studies Involving Protein Aggregation; CHAPTER 10: Aggregation and Immunogenicity of Therapeutic Proteins; CHAPTER 11: Regulatory Perspective on Aggregates as a Product Quality Attribute; INDEX; color plate"]
[null,null,null,"Sommario/riassunto","This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this ar"]
[null,"2.","Record Nr.",null,"UNISA996694510903316"]
[null,null,"Autore",null,"Nichols"]
[null,null,"Titolo",null,"Seamans Summons: An Embassie From The King Of Kings, A Peace-offering. Or, A Short Treatise Of Reconciliation : Being The Substance Of A Sermon Preached On Board Of The Soveraigne, When She Rode In The Downes. By (the Most Worthless Of The Lords Messengers, Whose Heart Runs Over In Longings And Labourings For The Good Of Souls At Sea, And On The Shore) Charles Nichols"]
[null,null,"Pubbl/distr/stampa",null,"ProQuest, UMI, 1655"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]