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[null,"1.","Record Nr.",null,"UNINA9910164945803321"]
[null,null,"Titolo",null,"Adverse drug reactions / / edited by Anne Lee"]
[null,null,"Pubbl/distr/stampa",null,"London ; ; Chicago : , : Pharmaceutical Press, , 2006"]
[null,null,"ISBN",null,"0-85711-113-2"]
[null,null,"Edizione",null,"[2nd ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (xxi, 474 p. )"]
[null,null,"Disciplina",null,"615/.7042"]
[null,null,"Soggetti",null,"Drugs - Side effects"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover -- Prelims -- Contents -- Preface -- Acknowledgements -- About the editor -- Contributors -- Chapter 1 - Introduction -- Epidemiology -- Classification and mechanisms -- Susceptibility -- Detection and diagnosis -- Healthcare professionals and adverse drug reactions -- References -- Further reading -- Chapter 2 - Side effects and patients -- Introduction -- Desire for information about side effects -- General perceptions -- Side effects and compliance -- Mandatory patient information leaflets -- Format of side-effect data for patients -- Key effects to consider when presenting side-effect data -- Patient reporting of ADRs -- The way forward -- References -- Further reading -- Chapter 3 - Pharmacogenetics and adverse drug reactions -- Introduction -- Adverse drug reactions -- Drug action -- Genetics revisited -- Genetic polymorphism and drug transporters -- Genetically determined pharmacodynamic variations -- Human leukocyte antigens and adverse drug reactions -- Utility of pharmacogenetics in the clinical setting -- References -- Further reading -- Glossary -- Chapter 4 - Adverse drug reactions in pregnancy -- Introduction -- Prescribing in pregnancy -- Drugs used to treat selected cardiovascular system disorders -- Drugs used to treat epilepsy -- Mental health disorders -- Drugs used in endocrine disorders -- Drugs used to treat infections -- Miscellaneous agents -- Summary -- References -- Further reading -- Glossary -- Chapter 5 - Drug-induced skin reactions -- Introduction -- Classification and mechanism -- Diagnosis -- Management points -- Exanthematous (erythematous) reactions -- Fixed drug eruption -- Urticaria and angio-oedema -- Acne -- Psoriasis and psoriasiform eruptions -- Purpura -- Vasculitis -- Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis -- Blistering drug eruptions -- Photosensitivity."]
[{"$nulls":4},"Lichenoid drug eruptions -- Pigmentary disorders -- Alopecia -- Hair gain -- Nail disorders -- References -- Further reading -- Chapter 6 - Gastrointestinal disorders -- Introduction -- The mouth -- The oesophagus -- Nausea and vomiting -- Stomach and duodenum -- Small intestine -- Colon -- Constipation -- Pancreatitis -- References -- Further reading -- Chapter 7 - Hepatic disorders -- Introduction -- Classification and mechanisms -- Signs and symptoms of liver disorders -- Risk factors -- Diagnosis of drug-induced liver damage -- Types of drug-induced liver disease -- Management of patients with drug-induced hepatic disease -- Prevention of drug-induced hepatic damage -- References -- Further reading -- Chapter 8 - Renal disorders -- Introduction -- Risk factors -- Diagnosis of drug-induced renal dysfunction -- Acute renal failure -- Chronic renal failure -- Nephrogenic diabetes insipidus -- Haemolytic uraemic syndrome -- Osmotic nephrosis -- Conclusion -- References -- Further reading -- Chapter 9 - Endocrine and metabolic disorders -- Introduction -- Drugs affecting thyroid function -- Medicines that may interfere with thyroid function tests -- Drugs affecting adrenal function -- Aldosterone synthesis -- Drugs affecting gonadotrophin release and gonadal function -- Hyperprolactinaemia -- Syndrome of inappropriate secretion of antidiuretic hormone -- Hyperglycaemia and diabetes -- Hypoglycaemia -- Disorders of fat metabolism -- References -- Further reading -- Chapter 10 - Respiratory disorders -- Introduction -- Nasal congestion -- Airway obstruction -- Parenchymal lung disorders -- Pulmonary oedema -- Pulmonary thromboembolism -- References -- Further reading -- Chapter 11 - Musculoskeletal disorders -- Introduction -- Muscle disorders -- Bone -- Joints -- Connective tissue -- References -- Further reading -- Chapter 12 - Blood disorders."]
[{"$nulls":4},"Introduction -- Aplastic anaemia -- Agranulocytosis -- Thrombocytopenia -- Pure red cell aplasia -- Haemolytic anaemia -- Megaloblastic anaemia -- References -- Further reading -- Chapter 13 - Mental health disorders -- Introduction -- Depression -- Psychosis -- Mania -- Behavioural toxicity -- Cognitive impairment -- Psychiatric manifestations of drug withdrawal reactions -- Use of SSRIs and venlafaxine in children and adolescents with major depressive disorder (MDD) -- Serotonin syndrome and neuroleptic malignant syndrome -- Management of drug-induced psychiatric disturbances -- References -- Further reading -- Chapter 14 - Cardiovascular effects -- Introduction -- Disorders of cardiac rhythm -- Disorders of systemic blood pressure -- Congestive heart failure -- Myocardial toxicity -- Pulmonary hypertension -- Stroke and heart attack risk -- References -- Further reading -- Chapter 15 - Neurological disorders -- Introduction -- Headache -- Effects on the neuromuscular junction and myasthenia gravis -- Seizures -- Coma and encephalopathy -- Neuropathies -- Guillain-Barré syndrome -- Drug-induced movement disorders -- Sudden sleep onset with dopaminergic drugs -- References -- Chapter 16 - Sexual dysfunction and infertility -- Introduction -- Infertility -- Sexual dysfunction -- References -- Further reading -- Index."]
[null,null,null,"Sommario/riassunto","Adverse reactions to medicines continue to present a considerable burden on healthcare, causing considerable morbidity and mortality. As well as knowing about the benefits of medicines, healthcare professionals need to understand the problem of adverse drug reactions and be aware of how they can be prevented and managed. The new edition of this essential and practical guide has been extensively revised and updated."]
[null,"2.","Record Nr.",null,"UNISA996543165703316"]
[null,null,"Autore",null,"Ross Cameron"]
[null,null,"Titolo",null,"Federalism and democratisation in Russia / / Cameron Ross"]
[null,null,"Pubbl/distr/stampa",null,"New York : , : Manchester University Press, , 2002"]
[null,null,"ISBN",null,"1-5261-2076-3"]
[null,null,"Descrizione fisica",null,"1 online resource (ix, 182 pages)"]
[null,null,"Disciplina",null,"321.8"]
[null,null,"Soggetti",null,"Democratization"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"1. Introduction -- 2. The Soviet legacy and Russian federalism 1985-1993 -- 3. Federalism and constitutional asymmetry -- 4. From ethnic to legal and economic separatism -- 5. Fiscal federalism and socio-economic asymmetry -- 6. Federalism under Putin -- 7. Federalism and political asymmetry: Regional elections and political parties -- 8. Federalism and political asymmetry: executive versus legislative power -- 9. From constitutional to political asymmetry: crafting authoritarian regimes in Russia's regions and republics -- 10. Conclusions."]
[null,null,null,"Sommario/riassunto","The collapse of communism in the Soviet Union and Eastern Europe has encouraged political scientists to re-examine the comparative literature on democratisation. A vast literature has now been produced comparing transitions from authoritarianism and democratisation in different parts of the world. However, there are two major omissions in the transition literature. First, the focus of research has primarily been on national level politics, and second, the relationship between federalism and democracy has largely been overlooked. This study seeks to redress this imbalance by moving the focus of research from the national level to the vitally important processes of institution building and democratisation at the local level and to the study of federalism and democratisation in Russia. Federal states are much more difficult to set up than unitary ones, and forging a new federal system at the same time as privatising the economy and trying to radically overhaul the political system has clearly made Russia's transition triply difficult. This book builds on Cameron Ross' earlier work, 'Regional Politics in Russia', by combining theoretical perspectives with empirical work to provide a comparative analysis of the electoral systems, party systems and governmental systems in the "]
[{"$nulls":4},"ethnic republics and regions and to assess the impact of theses different institutional arrangements on democratisation and federalism. Overall, this study argues that Russia's weak and asymmetrical form of federalism has played a major role in thwarting the consolidation of democracy. Federalism and democratisation in Russia exist in contradiction rather than harmony. In a vicious circle authoritarianism at the centre has been nourished by authoritarianism in the regions and vice versa. 'Elective dictatorships' and 'delegative democracies' are now well entrenched in many republics and authoritarian regimes are firmly established in a majority of the regions. This book will be vital reading for advanced undergraduate and graduate students of Russian politics and democratisation."]