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[null,"1.","Record Nr.",null,"UNISA996465430903316"]
[null,null,"Titolo",null,"Database Systems for Advanced Applications [[electronic resource] ] : 9th International Conference, DASFAA 2004, Jeju Island, Korea, March 17-19, 2003, Proceedings / / edited by YoonJoon Lee, Jianzhong Li, Kyu-Young Whang, Doheon Lee"]
[null,null,"Pubbl/distr/stampa",null,"Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2004"]
[null,null,"ISBN",null,"1-280-30693-9"]
[{"$nulls":4},"9786610306930"]
[{"$nulls":4},"3-540-24571-5"]
[null,null,"Edizione",null,"[1st ed. 2004.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XXIV, 932 p.)"]
[null,null,"Collana",null,"Lecture Notes in Computer Science, , 0302-9743 ; ; 2973"]
[null,null,"Disciplina",null,"005.74"]
[null,null,"Soggetti",null,"Database management"]
[{"$nulls":4},"Information storage and retrieval"]
[{"$nulls":4},"Application software"]
[{"$nulls":4},"Multimedia information systems"]
[{"$nulls":4},"Information technology"]
[{"$nulls":4},"Business—Data processing"]
[{"$nulls":4},"Database Management"]
[{"$nulls":4},"Information Storage and Retrieval"]
[{"$nulls":4},"Information Systems Applications (incl. Internet)"]
[{"$nulls":4},"Multimedia Information Systems"]
[{"$nulls":4},"IT in Business"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters and index."]
[null,null,"Nota di contenuto",null,"Invited Papers -- Access Methods -- Query Processing in XML -- Security and Integrity -- Query Processing in Temporal and Spatial Databases -- Semi-structured Databases -- Knowledge Discovery in Temporal and Spatial Databases -- XML and Multimedia Data Storage -- Temporal and Spatial Databases and Query Processing -- Web Computing -- Data Mining and Knowledge Discovery in Web I -- Query Processing and Optimization -- Classification and Clustering I -- Web Search I -- Classification and Clustering II -- Web Search II -- Mobile Databases I -- Parallel and Distributed Databases -- Multimedia "]
[{"$nulls":4},"Databases I -- Mobile Databases II -- Data Mining and Knowledge Discovery in Web II -- Multimedia Databases II -- Mobile Databases III."]
[null,null,null,"Sommario/riassunto","The 9th International Conference on Database Systems for Advanced Applications (DASFAA 2004) was held during March 17–19, 2004 on the beautiful Jeju island of Korea. The DASFAA conference provides an international forum for technical discussions among researchers, developers, and users of database - stems from academia, business, and industry. The main focus of DASFAA is on research in database theory, development of advanced DBMS technologies, and their advanced applications. A premier database conference in the Asia/Pacific region, DASFAA has been held every two years, and in many countries in the region. To promote the area further and to answer the needs of many participants, the steering committee decided to hold the conference annually. DASFAA 2004 was the first such annual conference. The conference was organized by the Special Interest Group on Databases (SIGDB) of the Korea Information Science Society and the Advanced Information Technology Research Center (AITrc) at KAIST – an engineering research center of excellence (ERC) supported by the Korea Science and Engineering Foundation (KOSEF). We had a number of sponsors who made generous contributions to make the conference successful. They are Oracle Korea, Samsung SDS, Korea Telecom Data, Inc. , the United States Air Force Office of Scientific Research, the Asian Office of Aerospace Research&Development, the Army Research Office-Far East, and the Korea Advanced Institute of Science and Technology (KAIST)."]
[null,"2.","Record Nr.",null,"UNINA9910820493303321"]
[null,null,"Titolo",null,"Drug repositioning : bringing new life to shelved assets and existing drugs / / edited by Michael J. Barratt, Donald E. Frail"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, : John Wiley & Sons, c2012"]
[null,null,"ISBN",null,"9786613673718"]
[{"$nulls":4},"9781118274392"]
[{"$nulls":4},"1118274393"]
[{"$nulls":4},"9781118274408"]
[{"$nulls":4},"1118274407"]
[{"$nulls":4},"9781280696756"]
[{"$nulls":4},"1280696753"]
[{"$nulls":4},"9781118274378"]
[{"$nulls":4},"1118274377"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (499 p.)"]
[null,null,"Disciplina",null,"338.4/76151"]
[null,null,"Soggetti",null,"Pharmaceutical industry - Economic aspects"]
[{"$nulls":4},"Drugs - Economic aspects"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Drug repositioning : the business case and current strategies to repurpose shelved candidates and marketed drugs / John Arrowsmith and Richard Harrison -- Opportunities and challenges associated with developing additional indications for clinical development candidates and marketed drugs / Donald Frail and Michael Barratt -- Clinical and operational considerations in repositioning marketed drugs and drug candidates / Damian O'Connell, David Sequeira, and Maria Miller -- Regulatory considerations and strategies for drug repositioning / Ken Phelps -- Computational and bioinformatic strategies for drug repositioning / Richard Mazzarella and Craig Webb -- Mining scientific and clinical databases to identify novel uses for existing drugs / Christos Andronis ... [et al.] -- Predicting the polypharmacology of drugs : identifying new uses through chemoinformatics, structural informatics and molecular modeling based approaches / Li Xie ... [et al.] -- Systematic phenotypic screening for novel synergistic combinations: a new paradigm for repositioning existing drugs / "]
[{"$nulls":4},"Margaret Lee -- Phenotypic in vivo screening to identify new, unpredicted indications for existing drugs and drug candidates / Michael Saporito, Christopher Lipinski, and Andrew Reaume -- Old drugs yield new discoveries : examples from the prodrug, chiral switch and site-selective deuteration strategies / Adam Morgan ... [et al.] -- Repurposing drugs for tropical diseases : case studies and open-source screening initiatives / Curtis Chong -- Drug repositioning efforts by non-profit foundations -- Business development strategies in the repositioning industry / Aris Persidis and Elizabeth Stark -- A case study in drug repositioning : Sosei / Akinori Mochizuki and Makiko Aoyama."]
[null,null,null,"Sommario/riassunto","The how's and why's of successful drug repositioning   Drug repositioning, also known as drug reprofiling or repurposing, has become an increasingly important part of the drug development process. This book examines the business, technical, scientific, and operational challenges and opportunities that drug repositioning offers. Readers will learn how to perform the latest experimental and computational methods that support drug repositioning, and detailed case studies throughout the book demonstrate how these methods fit within the context of a comprehensive drug repositioning s"]