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[null,"1.","Record Nr.",null,"UNISA996418199503316"]
[null,null,"Autore",null,"Winkelmann Stefanie"]
[null,null,"Titolo",null,"Stochastic dynamics in computational biology / / Stefanie Winkelmann, Christof SchuÌtte"]
[null,null,"Pubbl/distr/stampa",null,"Cham, Switzerland : , : Springer, , [2020]"]
[{"$nulls":4},"Â©2020"]
[null,null,"ISBN",null,"3-030-62387-4"]
[null,null,"Edizione",null,"[1st ed. 2020.]"]
[null,null,"Descrizione fisica",null,"1 online resource (XVIII, 272 p. 55 illus., 46 illus. in color.)"]
[null,null,"Collana",null,"Frontiers in Applied Dynamical Systems"]
[null,null,"Disciplina",null,"570.285"]
[null,null,"Soggetti",null,"Computational biology"]
[{"$nulls":4},"Systems biology"]
[{"$nulls":4},"Stochastic processes"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Introduction -- Well-mixed stochastic reaction kinetics -- Population scaling -- Temporal scaling -- Spatial scaling -- Summary and Outlook -- Mathematical background."]
[null,null,null,"Sommario/riassunto","The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems."]