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[null,"1.","Record Nr.",null,"UNISA996354436603316"]
[null,null,"Autore",null,"Justus Xenia"]
[null,null,"Titolo",null,"Selbstregulation im virtuellen Studium : Volitionale Regulation, Lernzeit und Lernstrategien in Online-Seminaren [[electronic resource]] / Xenia Justus"]
[null,null,"Pubbl/distr/stampa",null,"Münster, : Waxmann, 2017"]
[null,null,"ISBN",null,"3-8309-8608-4"]
[null,null,"Edizione",null,"[1st, New ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (200 p.)"]
[null,null,"Collana",null,"Pädagogische Psychologie und Entwicklungspsychologie ; 96"]
[null,null,"Soggetti",null,"Lernzeit"]
[{"$nulls":4},"Lernstrategien"]
[{"$nulls":4},"Hochschulseminar"]
[{"$nulls":4},"Lehramtsstudierende"]
[{"$nulls":4},"E-Learning"]
[{"$nulls":4},"Blended Learning"]
[{"$nulls":4},"Handlungsregulation"]
[{"$nulls":4},"Wiederholungsstrategien"]
[{"$nulls":4},"Elaborationsstrategien"]
[{"$nulls":4},"Pädagogische Psychologie"]
[{"$nulls":4},"Empirische Bildungsforschung"]
[null,null,"Lingua di pubblicazione",null,"Tedesco"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Die eigenständige Gestaltung und Bewältigung wesentlicher Anteile des Studiums bringen für Studierende zahlreiche Vorteile mit sich. Besonders viele Herausforderungen bestehen in den virtuellen Lernumgebungen, in denen Studentinnen und Studenten aufgrund der geringen sozialen und organisatorischen Einbindung auf eine effiziente Handlungsregulation angewiesen sind. Vor allem die Erreichung der Lernziele in asynchronen Online-Seminaren setzt eine starke selbstregulatorische Kompetenz voraus.  Dieses Buch befasst sich mit den Lernprozessen in virtuellen Lernumgebungen aus der Perspektive der Selbstregulation. Im Zentrum der durchgeführten empirischen Studie steht dabei die Rolle der volitionalen Kompetenzen und deren Einfluss auf das Auftreten von subjektiven Handlungsregulationsproblemen, die Lernzeit sowie die Nutzung von "]
[{"$nulls":4},"kognitiven Lernstrategien.  Die Ergebnisse zeigen, dass volitionale Kompetenzen zum günstigen Lernverhalten in webbasierten Umgebungen statistisch signifikant beitragen. Aus den Befunden lassen sich wichtige Ansatzpunkte zur Optimierung der didaktischen Gestaltung der virtuellen Lehre ableiten."]
[null,"2.","Record Nr.",null,"UNINA9910137205603321"]
[null,null,"Autore",null,"Konrad Krzewski"]
[null,null,"Titolo",null,"Molecular mechanisms regulating cytotoxic lymphocyte development and function and their associations to human diseases"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2015"]
[{"$nulls":4},"France : , : Frontiers Media SA, , 2015"]
[null,null,"ISBN",null,"9782889192793"]
[null,null,"Descrizione fisica",null,"1 online resource (163 pages) : illustrations; digital, PDF file(s)"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Soggetti",null,"Microbiology & Immunology"]
[{"$nulls":4},"Biology"]
[{"$nulls":4},"Health & Biological Sciences"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,null,"Sommario/riassunto","Cytotoxic lymphocytes, comprised of NK cells and cytotoxic T cells, play a pivotal role in immune defense. By directed release of perforin-containing lytic granules, NK and cytotoxic T cells can eradicate pathogen-infected, tumorigenic, and otherwise stressed cells. By the virtue of cytokine and chemokine secretion, they can influence other cells of the immune system. Through these processes, cytotoxic lymphocytes also contribute to the maintenance of immune homeostasis. In recent years, much progress has been made with respect to the mechanisms by which cytotoxic lymphocytes develop, differentiate, and exert their effector functions. In a clinical perspective, a wide variety of mutations impairing cytotoxic lymphocyte development and/or function have been associated with immunodeficiency and severe diseases in humans. Aberrant activity of cytotoxic T cells and/or NK cells has been linked to an increased susceptibility to viral infections, persistent inflammation, cancer and autoimmunity. In addition, lymphocyte cytotoxic activity may be harnessed therapeutically to target tumor cells in different adoptive cellular therapy regimes, or through the use of recombinant antibodies. Still, a number of questions remain in regards to how cytotoxic lymphocytes develop, their relationships and plasticity, as well as the mechanisms dictating target cell discrimination, lytic granule release and induction of target cell death. In this Research Topic we encourage "]
[{"$nulls":4},"submission of research articles, reviews, perspectives, or methods on cytotoxic lymphocyte development and function, their relation to the pathogenesis or treatment of different diseases, as well as comparison between similarities and/or differences in their effector functions. Considering the clinical significance of NK cells and cytotoxic T cells, we aim to provide a range of articles summarizing the current knowledge on the identification and elucidation of the mechanisms governing cytotoxic lymphocyte activity."]