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[null,"1.","Record Nr.",null,"UNISA996209101203316"]
[null,null,"Titolo",null,"Notar"]
[null,null,"Pubbl/distr/stampa",null,"Deutscher Notarverein"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Periodico"]
[null,"2.","Record Nr.",null,"UNINA9910967078303321"]
[null,null,"Titolo",null,"Methylmercury : formation, sources, and health effects / / Andrew P. Clampet, editor"]
[null,null,"Pubbl/distr/stampa",null,"New York, : Nova Science Publishers, c2011"]
[null,null,"ISBN",null,"1-61122-217-6"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (217 p.)"]
[null,null,"Collana",null,"Environmental science, engineering and technology"]
[{"$nulls":4},"Environmental health-- physical, chemical and biological factors"]
[null,null,"Disciplina",null,"615.9/25663"]
[null,null,"Soggetti",null,"Methylmercury - Environmental aspects"]
[{"$nulls":4},"Methylmercury - Toxicology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Intro -- METHYLMERCURY  FORMATION, SOURCES AND HEALTH EFFECTS -- METHYLMERCURY  FORMATION, SOURCES AND HEALTH EFFECTS -- CONTENTS -- PREFACE -- Chapter 1    THE ROLE OF SELENIUM IN MITIGATING MERCURY TOXICITY -- ABSTRACT -- INTRODUCTION -- MERCURY BIOGEOCHEMISTRY AND HUMAN EXPOSURES -- SELENIUM NUTRITION AND PHYSIOLOGY -- MOLECULAR MECHANISMS OF MERCURY-SELENIUM INTERACTIONS -- Silencing of Selenium (SOS-1) -- Sequestration of Selenium (SOS-2) -- SOS-1 and SOS-2 Induced Generation of Apoptosis Initiators -- PROTECTIVE ROLE OF DIETARY SELENIUM AGAINST MERCURY TOXICITY -- FISH CONSUMPTION ADVISORIES -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 2    FISH AS A DIETARY SOURCE OF MERCURY AND METHYLMERCURY, RISKS AND BENEFITS -- CHEMICAL AND PHYSICAL PROPERTIES OF MERCURY -- INORGANIC FORMS OF MERCURY -- ORGANIC FORMS OF MERCURY -- SOURCES OF MERCURY IN THE ENVIRONMENT -- NATURAL SOURCES -- ANTHROPOGENIC RELEASES FROM THE MOBILIZATION OF MERCURY IMPURITIES IN MATERIALS -- ANTHROPOGENIC RELEASES FROM MERCURY USED IN PRODUCTS AND PROCESSES -- EMISSION OF MERCURY TO THE AIR -- EMISSION OF MERCURY TO THE WATER -- EMISSION OF MERCURY TO THE SOIL -- RE-MOBILIZATION OF HISTORIC ANTHROPOGENIC MERCURY -- GLOBAL CYCLING, TRANSPORT AND FATE OF MERCURY IN THE ENVIRONMENT -- MERCURY SPECIES AND TRANSFORMATION IN AQUATIC ENVIRONMENT -- POTENTIAL SOURCES OF EXPOSURE AND OCCURRENCE OF MERCURY IN HUMAN TISSUES -- RISKS AND BENEFITS "]
[{"$nulls":4},"OF EATING FISH -- FISH CONSUMPTION LIMITS -- TOXICITY OF MERCURY AND METHYLMERCURY -- Pharmacokinetics Effects -- ACUTE TOXICITY -- CHRONIC TOXICITY -- DEVELOPMENTAL TOXICITY -- MUTAGENICITY, NEUROTOXICITY AND CYTOTOXICITY -- DISTRIBUTION OF MERCURY IN FISH SAMPLES -- HUMAN HEALTH RISK ASSESSMENT -- REFERENCES."]
[{"$nulls":4},"Chapter 3    INEXPENSIVE LOW-COST MERCURY SPECIATION BY HYDRIDE GENERATION ATOMIC ABSORPTION SPECTROMETRY AFTER ION EXCHANGE SEPARATION IN A FIA SYSTEM (FIA-IE-HG-AAS) -- ABSTRACT -- 1. INTRODUCTION -- 2. EXPERIMENTAL PROCEDURE -- 2.1. Safety Considerations -- 2.2. Reagents -- 2.3. Instrumentation -- 2.4. Analytical Procedure -- Retention and Elution Experiments in Batch Mode -- Analysis of Total Mercury by FIA-HG-QFAAS -- Analysis of CH3Hg+ and Hg2+ by FIA-IE-HG-QFAAS -- 3. RESULTS AND DISCUSSION -- 3.1. Optimisation of the FIA-HG-QFAAS Measuring System -- 3.2. Experiments in Batch Mode with the Dowex M-41 Resin -- 3.3. Experiments On-Line: Optimization of the FIA-IE-HG-QFAAS System for Mercury Speciation -- Preliminary Experiments -- Selection of the Best Microcolumn Geometry -- Selection of the Best Elution Conditions -- 3.4. Analytical Figures of Merit -- 3.5. Applicability of the Method: Analysis of Real Samples Doped with the Analytes -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4    CATHEPSIN-DEPENDENT NEURONAL DEATH PATHWAYS INDUCED BY METHYLMERCURY -- ABSTRACT -- INTRODUCTION -- CATHEPSIN B IN NEURONAL DEATH -- CATHEPSIN B IN METHYLMERCURY-INDUCED NEURONAL DEATH -- INVOLVEMENT OF MICROGLIAL CATHEPSIN B IN PROCESSING OF INTERLEUKIN-1β -- CATHEPSIN D IN NEURONAL DEATH -- CATHEPSIN D IN METHYLMERCURY-INDUCED NEURONAL DEATH -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5    NOT ONLY CONCENTRATIONS MATTER: SOME PRACTICAL CONSIDERATIONS OF IN VITRO MEHG TOXICITY STUDIES -- ABSTRACT -- INTRODUCTION -- MATERIALS AND METHODS -- RESULTS -- Effects of Cell Density on Apparent Cytotoxicity -- Effects of Medium Volumn on Apparent Cytotoxicity -- Temporal \"Commitment Point\" of Cell Death -- CONCLUSION -- Kinetics of Toxicity by a Cytotoxic Agent -- Commitment Point: A Proposed Experimental Application -- ACKNOWLEDGMENTS."]
[{"$nulls":4},"REFERENCES -- Chapter 6    METHYLMERCURY AND TOTAL MERCURY CONTAMINATION IN AN AQUATIC ECOSYSTEM OF HG-MINING RIVER IN GUIZHOU, CHINA -- ABSTRACT -- INTRODUCTION -- MATERIALS AND METHODS -- Sampling Site and Sample Collection -- Trophic Levels (TLs) Calculation -- Chemical Analysis -- RESULTS AND DISCUSSION -- Trophic Levels of Organisms from Xiaxi River -- Mercury Concentration and Speciation in Sediment -- Mercury Speciation in Biota -- CONCLUSION -- REFERENCES -- Chapter 7    MERCURY METHYLATION VERSUS DEMETHYLATION: MAIN PROCESSES INVOLVED -- ABSTRACT -- 1. INTRODUCTION -- 1.1. Organomercury Compounds -- 2. MERCURY METHYLATION/DEMETHYLATION PROCESSES -- 2.1. Mercury Methylation Processes -- 2.1.1. Chemical Methylation - Abiotic Processes -- 2.1.2. Biotic Processes -- i. Environmental Factors that Affect Mercury Biotic Methylation -- 2.2. Mercury Demethylation Processes -- 2.2.1. Chemical Demethylation - Abiotic Processes -- 2.2.2. Biotic Processes -- i. Reductive Methylmercury Degradation -- ii. Organization of the Mer Operon -- iii. Oxidative Methylmercury Demethylation -- iv. Environmental Factors that Affect Mercury Biotic Demethylation -- 3. CONCLUSIONS -- REFERENCES -- Chapter 8    MEHG-EXPOSURE THROUGH SEAFOOD CONSUMPTION: CHOLINERGIC MUSCARINIC RECEPTOR AS A TARGET OF TOXICITY AND POTENTIAL "]
[{"$nulls":4},"BIOMARKER OF CNS EFFECTS -- ABSTRACT -- INTRODUCTION -- AIM AND EXPERIMENTAL PROCEDURES -- MAIN FINDINGS -- In Vivo Studies -- In Vitro Studies on Brain and Lymphocyte MRs -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- INDEX -- Blank Page."]
[null,null,null,"Sommario/riassunto","Methylmercury (MeHg) is considered a major environmental pollutant that bioaccumulates in fish tissues in direct relation to their age and predatory status. This title presents research from across the globe in the study of methymercury, including the role of selenium in mitigating mercury toxicity."]