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[null,"1.","Record Nr.",null,"UNINA990008763090403321"]
[null,null,"Titolo",null,"L'automazione nella lavorazione delle materie plastiche / Menges, Recker"]
[null,null,"Pubbl/distr/stampa",null,"Milano : Tecniche nuove, c1989"]
[null,null,"ISBN",null,"88-7081-366-5"]
[null,null,"Descrizione fisica",null,"XVII, 536 p. : ill. ; 25 cm"]
[null,null,"Collana",null,"Materie plastiche"]
[null,null,"Disciplina",null,"620.192"]
[null,null,"Locazione",null,"DINPA"]
[null,null,"Collocazione",null,"R19"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNISA996207922203316"]
[null,null,"Titolo",null,"Bioinorganic medicinal chemistry [[electronic resource] /] / edited by Enzo Alessio"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim, Germany, : Wiley-VCH, c2011"]
[null,null,"ISBN",null,"3-527-63312-X"]
[{"$nulls":4},"1-283-37048-4"]
[{"$nulls":4},"9786613370488"]
[{"$nulls":4},"3-527-63311-1"]
[{"$nulls":4},"3-527-63310-3"]
[null,null,"Descrizione fisica",null,"1 online resource (442 p.)"]
[null,null,"Disciplina",null,"615.2"]
[null,null,"Soggetti",null,"Pharmaceutical chemistry"]
[{"$nulls":4},"Bioinorganic chemistry"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index"]
[null,null,"Nota di contenuto",null,"Bioinorganic Medicinal Chemistry; Contents; List of Contributors; 1: Medicinal Inorganic Chemistry: State of the Art, New Trends, and a Vision of the Future: Nicola J. Farrer and Peter J. Sadler; 1.1: Introduction; 1.1.1: Metals in the Body: Essential Elements and Diseases of Metabolism; 1.1.2: Metals as Therapeutic Agents; 1.2: Antimicrobial Agents; 1.3: Antiviral Agents; 1.4: Systemic and Metabolic Diseases Including Inflammation; 1.4.1: Diabetes and Obesity; 1.4.2: Metal Homeostasis and Related Diseases; 1.5: Metal Chelating Agents; 1.6: Antiarthritic Drugs and Inflammation"]
[{"$nulls":4},"1.7: Bipolar Disorder1.8: Anticancer Agents; 1.8.1: PtII  Cytotoxic Agents; 1.8.2: PtIV  Prodrugs; 1.8.3: Photoactivatable PtIV  Complexes; 1.8.4: Ruthenium; 1.8.4.1: Interaction with Plasma Proteins; 1.8.4.2: Ruthenium Arenes; 1.8.5: Osmium; 1.8.6: Titanium; 1.8.7: Gold; 1.8.8: Tin; 1.8.9: Gallium; 1.8.10: Arsenic; 1.8.11: Copper; 1.8.12: Zinc; 1.8.13: Bismuth; 1.8.14: Molybdenum; 1.8.15: Photosensitizers: Porphyrins; 1.9: Small Molecule Delivery and Control; 1.9.1: Nitric Oxide (NO); 1.9.2: Carbon Monoxide (CO); 1.10: Diagnostic Agents; 1.11: Veterinary Medicinal Inorganic Chemistry"]
[{"$nulls":4},"1.12: Conclusions and Vision2: Targeting Strategies for Metal-Based Therapeutics: Julia F. Norman and Trevor W. Hambley; 2.1: Introduction; 2.2: Physiological Targeting; 2.2.1: Antitumor Drugs "]
[{"$nulls":4},"Targeting Tumor Hypoxia; 2.2.2: Antitumor Drugs Targeting Vascular Structure; 2.2.3: Antitumor Drugs Targeting Tumor pH; 2.2.4: Light Activated Prodrugs; 2.3: Molecular Targeting; 2.3.1: Protein and Peptide Targeting; 2.3.1.1: Protein Receptor Binding; 2.3.2: Peptide Tethering; 2.3.2.1: Directing Effects; 2.3.3: Selective Activation; 2.3.4: DNA Targeting; 2.3.4.1: Duplex DNA Sequence Selectivity"]
[{"$nulls":4},"2.3.4.2: Telomeric Targeting2.4: Immunological Targeting; 2.4.1: Antigen Targeting; 2.4.2: Antibody Tethering; 2.5: Concluding Remarks; 3: Current Status and Mechanism of Action of Platinum-Based Anticancer Drugs: Shanta Dhar and Stephen J. Lippard; 3.1: Introduction; 3.1.1: Platinum Chemotherapy and Cancer; 3.1.2: Palette of Current Platinum Chemotherapeutic Drugs; 3.1.3: Early History of Cisplatin and Approved Platinum Drugs for the Clinic; 3.2: Mechanism of Action of Cisplatin; 3.2.1: Cisplatin Accumulation; 3.2.2: Cisplatin Activation; 3.2.2.1: Binding to DNA Targets"]
[{"$nulls":4},"3.2.2.2: Binding to Non-DNA Targets3.2.3: Cellular Processing of Platinum-DNA Adducts; 3.2.3.1: Cytotoxicity Associated with High Mobility Group (HMG) Proteins; 3.2.3.2: Cytotoxicity Associated with Non-HMG Proteins; 3.3: Limitations of Current Platinum-Based Compounds: New Strategies; 3.4: Novel Concepts in the Development of Platinum Antitumor Drugs; 3.4.1: Functionalized Single-Walled Carbon Nanotubes (SWNTs) as Vehicles for Delivery of Pt(IV)-Prodrugs; 3.4.2: Targeted Nanoparticles for Delivery of Cisplatin for Prostate Cancer"]
[{"$nulls":4},"3.4.3: Gold Nanoparticles as Delivery Vehicles for Platinum Compounds"]
[null,null,null,"Sommario/riassunto","This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic."]