{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":3,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":45,"n_cols":5,"rows_kept":45,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[4,2,4,3],[5,2,5,3],[6,2,6,3],[7,2,7,3],[9,2,9,3],[9,4,9,5],[10,2,10,3],[10,4,10,5],[11,2,11,3],[11,4,11,5],[12,2,12,3],[13,2,13,3],[14,2,14,3],[15,2,15,3],[16,2,16,3],[17,2,17,3],[18,2,18,3],[21,2,21,3],[22,2,22,3],[25,2,25,3],[25,4,25,5],[26,2,26,3],[26,4,26,5],[27,2,27,3],[28,2,28,3],[29,2,29,3],[30,2,30,3],[31,2,31,3],[32,2,32,3],[33,2,33,3],[37,2,37,3],[38,2,38,3],[42,2,42,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNISA990005854730203316"]
[null,null,"Autore",null,"CONRAD, Joseph"]
[null,null,"Titolo",null,"1: Typhon / Joseph Conrad ; traduit de l'anglais par André Gide"]
[null,null,"Pubbl/distr/stampa",null,"Paris : Gallimard, 1930"]
[null,null,"Descrizione fisica",null,"224 p. ; 18 cm"]
[null,null,"Collocazione",null,"VII.3.A. 2287 1"]
[null,null,"Lingua di pubblicazione",null,"Francese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"2.","Record Nr.",null,"UNISA990000858690203316"]
[null,null,"Autore",null,"ROCHE, Daniel"]
[null,null,"Titolo",null,"Il linguaggio della moda / Daniel Roche"]
[null,null,"Pubbl/distr/stampa",null,"Torino, : Einaudi, 1991"]
[null,null,"ISBN",null,"88-06-12632-6"]
[null,null,"Descrizione fisica",null,"X, 519 p., [12] carte di tav. : ill. ; 22 cm"]
[null,null,"Collana",null,"Biblioteca di cultura storica ; 188"]
[null,null,"Disciplina",null,"391.00944"]
[null,null,"Soggetti",null,"Abbigliamento - Francia - Sec. 17.-18"]
[null,null,"Collocazione",null,"II.5. 1322(III A Coll. 21/188)"]
[{"$nulls":4},"II.5. 1322a(III A Coll. 21/188 A)"]
[{"$nulls":4},"II.5. 1322b(III A Coll. 21/188 BIS)"]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Traduzione di Sergio Luzzatto"]
[null,"3.","Record Nr.",null,"UNINA9910300347903321"]
[null,null,"Titolo",null,"Management of Castration Resistant Prostate Cancer / / edited by Fred Saad, Mario A. Eisenberger"]
[null,null,"Pubbl/distr/stampa",null,"New York, NY : , : Springer New York : , : Imprint : Humana, , 2014"]
[null,null,"ISBN",null,"1-4939-1176-7"]
[null,null,"Edizione",null,"[1st ed. 2014.]"]
[null,null,"Descrizione fisica",null,"1 online resource (336 p.)"]
[null,null,"Collana",null,"Current Clinical Urology, , 2197-7194"]
[null,null,"Disciplina",null,"616.9946306"]
[null,null,"Soggetti",null,"Urology"]
[{"$nulls":4},"Oncology"]
[{"$nulls":4},"Interventional radiology"]
[{"$nulls":4},"Interventional Radiology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references at the end of each chapters and index."]
[null,null,"Nota di contenuto",null,"Introduction - Castration Resistant Prostate Cancer: A Rapidly Expanding Clinical State and a Model for New Therapeutic Opportunities -- Evolution of Clinical States and the Castration Resistant Clinical Paradigm -- Molecular Mechanisms of Prostate Cancer Progression after Castration -- New Imaging Modalities -- Androgen Receptor Biology in Castration Resistant Prostate Cancer -- The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer -- Approaches Targeting Androgen Synthesis (CYP 17 inhibitors) -- Cytotoxic Chemotherapy (Taxanes and Taxane Combinations) -- The Emerging Role of Immunotherapy in Castrate Resistant Prostate Cancer -- Bone Targeted Therapy: Rationale and Current Status -- Radium-223 and Other Radiopharmaceuticals in Prostate Cancer -- Introduction -- Phase I/II targeted treatments -- Defining Clinical Endpoints in Castration-resistant Prostate Cancer -- Angiogenesis Inhibition in Castration Resistant Prostate Cancer -- Co-targeting Adaptive Survival Pathways -- Targeting the PI3K/AKT/mTOR Pathway in Prostate Cancer -- PARP Inhibitors -- Targeting C-Met/VEGF in Castration Resistant Prostate Cancer -- Epigenetics in Castration Resistant Prostate Cancer -- Undifferentiated Prostate Cancer and the Neuroendocrine Phenotype -- Strategies Addressing Quality of Life: Patient Reported Outcome and Symptoms Management -- Evidence-Based Therapeutic Approaches for mCRPC patients: Rational Sequence of Standard Treatment Options and Design for "]
[{"$nulls":4},"Future Drug Development."]
[null,null,null,"Sommario/riassunto","This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in-depth review of proven therapeutic options, including bone-targeted therapies, immunotherapy, chemotherapy and hormonal based therapies. Combination therapy as well as novel targeted approaches presently under investigation are also reviewed. The text provides up-to-date guidelines and algorithms for the management of CRPC based on international guidelines presently available as well as evidence-based medicine. As a concise yet comprehensive summary of the current status of the field, Management of Castration Resistant Prostate Cancer serves as a very useful resource for physicians and researchers dealing with this challenging malignancy."]