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[null,"1.","Record Nr.",null,"UNINA9910144742803321"]
[null,null,"Titolo",null,"The GTPase superfamily [[electronic resource] /] / [editors, Joan Marsh (organizer) and Jamie Goode]"]
[null,null,"Pubbl/distr/stampa",null,"Chichester ; ; New York, : Wiley, 1993"]
[null,null,"ISBN",null,"1-282-34785-3"]
[{"$nulls":4},"9786612347856"]
[{"$nulls":4},"0-470-51445-0"]
[{"$nulls":4},"0-470-51446-9"]
[null,null,"Descrizione fisica",null,"1 online resource (302 p.)"]
[null,null,"Collana",null,"Ciba Foundation symposium ; ; 176"]
[null,null,"Disciplina",null,"574.19"]
[{"$nulls":4},"574.19245"]
[null,null,"Soggetti",null,"G proteins"]
[{"$nulls":4},"Guanosine triphosphatase"]
[{"$nulls":4},"Guanosine triphosphatase genes"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Symposium on the GTPase superfamily, held at the Ciba Foundation, London, 17-19 November 1992\"--P. [v]."]
[{"$nulls":4},"\"A Wiley-Interscience publication.\""]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and indexes."]
[null,null,"Nota di contenuto",null,"THE GTPase SUPERFAMILY; Contents; Introduction; Three-dimensional structure and properties of wild-type and mutant H-ras-encoded p21; Elongation factors in protein synthesis; RAS function and protein kinase cascades; Cell transformation by ras and regulation of its protein product; Identification of ras targets using a genetic approach; G proteins in signal transduction: the regulation of phospholipase C; The G protein cascade of visual transduction: kinetics and regulation; General discussion I Voltage-dependent Ca2+ channels as GAPS; Regulators of small GTPases"]
[{"$nulls":4},"A GTPase cycle in initiation of protein translocation across the endoplasmic reticulum membraneA cell-physiological description of GE, a GTP-binding protein that mediates exocytosis; Dynamin, a GTPase involved in the initial stages of endocytosis; The VPS1 protein is a dynamin-like GTPase required for sorting proteins to the yeast vacuole; General discussion II : Ras-mediated signalling pathway during vulval development in Caenorhabditis elegans; The cycle of SEC4 function in vesicular transport; Mx proteins: GTPases involved in the "]
[{"$nulls":4},"interferon-induced antiviral state"]
[{"$nulls":4},"Should the tubulins be members of the GTPase superfamily?Final general discussion; Summing-up; Index of contributors; Subject index"]
[null,null,null,"Sommario/riassunto","Using a multidisciplinary approach, it features contributions and discussions of the latest research from leading scientists working on all aspects of GTPase activity. Covers all known members of the important superfamily of enzymes--the GTPases. Considers numerous key cellular functions and how they are regulated by GTPases. Also describes various regulatory proteins that modulate GTPase activity."]
[null,"2.","Record Nr.",null,"UNIORUON00313769"]
[null,null,"Autore",null,"ALBERTINI, Luigi"]
[null,null,"Titolo",null,"Epistolario, 1911-1926. 1.: Dalla guerra di Libia alla grande guerra / Luigi Albertini ; a cura di Ottavio Barié"]
[null,null,"Pubbl/distr/stampa",null,"[Milano], : A. Mondadori"]
[null,null,"Descrizione fisica",null,"XXXIV, 386 p. ; 22 cm."]
[null,null,"Lingua di pubblicazione",null,"Italiano"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"3.","Record Nr.",null,"UNINA9910220138103321"]
[null,null,"Titolo",null,"Investing in our children : what we know and don't know about the costs and benefits of early childhood interventions / / Lynn A. Karoly ... [et al.]"]
[null,null,"Pubbl/distr/stampa",null,"Santa Monica, CA, : Rand, 1998"]
[null,null,"ISBN",null,"1-282-45132-4"]
[{"$nulls":4},"9786612451324"]
[{"$nulls":4},"0-8330-4326-9"]
[{"$nulls":4},"0-585-36139-8"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (185 p.)"]
[null,null,"Disciplina",null,"362.7/0973"]
[null,null,"Soggetti",null,"Children with social disabilities - Services for - United States - Evaluation"]
[{"$nulls":4},"Children with social disabilities - Services for - United States - Costs"]
[{"$nulls":4},"Child welfare - United States"]
[{"$nulls":4},"Public welfare - United States"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Funded by a grant from  The California Wellness Foundation.\""]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. 143-149)."]
[null,null,"Nota di contenuto",null,"Cover; Preface; Contents; Figures; Tables; Summary; Acknowledgements; Chapter One - Introduction; The Importance of Early Childhood Education; What is Early Intervention?; Goals and Approaches of This Study; Organization of This Report; Chapter Two - Targeted Early Intervention Programs and Their Benefits; The Origins of Early Intervention; From Theory to Practice: Determining Which Interventions Work; Historical Review of Targeted Early Intervention Programs; First Models for Targeted Early Intervention Programs; The Next Generation of Targeted Early Intervention Programs"]
[{"$nulls":4},"More Recent Models of Targeted Early Intervention Summary of Findings; Chapter Three - Comparing Costs, Savings, and Benefits; Programs Selected for Analysis; Comparing Program Costs to the Government Savings the Programs Generate; Additional Monetary Benefits to the Rest of Society; Sensitivity of Results to Discount Rate; Findings from Cost-Savings and Cost-Benefit Analyses; Chapter Four -Issues Relevant to Investment Decisions; What We Know About Early Childhood Intervention; What We Don't Know About Early Childhood Intervention; Next Steps for Research and Policy"]
[{"$nulls":4},"Appendix A - Calculation of the Costs and Benefits of the Elmira Prenatal/Early Infancy Project Appendix B - Calculation of the Costs and Benefits of the Perry School; References"]
[null,null,null,"Sommario/riassunto","There is increasing evidence that the first few years after birth are particularly important in child development and present opportunities for enrichment but also vulnerabilities do to poverty and other social stressors. Elected officials have begun proposing potentially costly programs to intervene early in the lives of disadvantaged children. Have such interventions been demonstrated to yield substantial benefits? To what extent might they pay for themselves through lower welfare and criminal justice costs incurred by participating children as they grow into adults? This study synthesizes"]