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[null,"1.","Record Nr.",null,"UNINA9910404149203321"]
[null,null,"Autore",null,"Dove E. S (Edward S.)"]
[null,null,"Titolo",null,"Regulatory stewardship of health research : navigating participant protection and research promotion / / Edward S. Dove"]
[null,null,"Pubbl/distr/stampa",null,"Northampton : , : Edward Elgar Publishing, , 2020"]
[null,null,"ISBN",null,"1-78897-535-9"]
[null,null,"Descrizione fisica",null,"1 online resource (232 pages)"]
[null,null,"Collana",null,"Elgar studies in law and regulation"]
[null,null,"Disciplina",null,"613"]
[null,null,"Soggetti",null,"Health - Research"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Includes index."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Contents: 1. Introduction -- 2. Conceptual framework - setting the scene for 'protection' and 'promotion' -- 3. The making of recs as health research regulators -- 4. Anthropology of regulation -- 5. Operationalising 'next-generation' health research regulation - what is happening in practice? -- 6. Charting a framework for regulatory stewardship -- 7. Conclusion -- Index."]
[null,null,null,"Sommario/riassunto","\"This timely book examines the interaction of health research and regulation with law through empirical analysis and the application of key anthropological concepts to reveal the inner workings of human health research. Through ground-breaking empirical inquiry, Regulatory Stewardship of Health Research explores how research ethics committees (RECs) work in practice to both protect research participants and promote ethical research. This thought-provoking book provides new perspectives on the regulation of health research by demonstrating how RECs and other regulatory actors seek to fulfil these two functions by performing a role of 'regulatory stewardship'. This involves guiding researchers through stages of research approval, as well as seeking to maximise benefits for participants and society while minimising risks. Arguing that participant protection and research promotion should rightly be treated as twin objectives for health research regulators, this book asserts that there is a need for more overt recognition of the importance and function of the deliberative space in which RECs can negotiate the risks relevant to a research application. This book is a key resource for academics and students interested in health research and regulation, and the dynamic interaction of ethics and the law. Regulators and policy-makers will also find it to be an insightful and illuminating text for the practical "]
[{"$nulls":4},"insights that it reveals about research governance in action\"--"]
[null,"2.","Record Nr.",null,"UNIORUON00134345"]
[null,null,"Autore",null,"DMITRIEV, S. S."]
[null,null,"Titolo",null,"Cestmenskaja pobeda / S. S. Dmitriev"]
[null,null,"Pubbl/distr/stampa",null,"Ogiz, : Gosudarstvennoe izdatel'stvo politiceskoje litaretury, 1945"]
[null,null,"Descrizione fisica",null,"43 p. ; 18 cm"]
[null,null,"Classificazione",null,"OTT VI"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,"3.","Record Nr.",null,"UNINA9910249958903321"]
[null,null,"Autore",null,"Svensson-Coelho Maria"]
[null,null,"Titolo",null,"Diversity, prevalence, and host specificity of avian Plasmodium and Haemoproteus in a Western Amazon assemblage / / Maria Svensson-Coelho, John G. Blake, Bette A. Loiselle, Amanda S. Penrose, Patricia G. Parker, and Robert E. Ricklefs"]
[null,null,"Pubbl/distr/stampa",null,"The American Ornithologists' Union"]
[null,null,"Disciplina",null,"598.8"]
[null,null,"Soggetti",null,"Passeriformes - Parasites - Ecuador"]
[{"$nulls":4},"Host-parasite relationships"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","We used PCR and DNA sequencing to screen for haemosporidian parasites (Haemoproteus and Plasmodium) in 2,488 individual birds from 104 species and 22 families, primarily understory suboscine passerines, captured in a lowland Amazonian forest in Ecuador as a first major step to understanding the transmission dynamics of this cosmopolitan group of parasites in this region. To assess diversity of avian haemosporidia in our study site, we identified putative evolutionary lineages of haemosporidia using the mtDNA gene cytochrome b (cyt b). We sampled birds over 9 years, which allowed us to assess annual variation in haemosporidian prevalence. Additionally, we investigated among-species variation in prevalence and tested relationships between traits of hosts and prevalence of haemosporidia in a comparative analysis. Finally, we estimated host specificity of each recovered parasite lineage and compared several indices with different details of host information. Prevalence of haemosporidia was 21.7% when we combined years and ranged from 5.6% to 91.2% among well-sampled host species. Prevalence varied significantly among years, ranging from 14.5% in 2006 to 33.2% in 2009. The hypothesis that haemosporidian prevalence increases with level of sexual dimorphism and decreases with foraging height of a host species received some support. We identified 65 unique cyt b haplotypes, some of which we considered variation within the same evolutionary lineage. In total, we "]
[{"$nulls":4},"defined 45 putative evolutionary lineages based on 363 identified parasites. Fourteen haplotypes were identical to haplotypes found elsewhere, sometimes on different continents. Host specificity varied greatly among parasite lineages. Collectively, our findings indicate that within a local Neotropical assemblage of avian haemosporidia, community organization is highly complex and part of this complexity can be attributed to differences in host life history; diversity, particularly of Plasmodium spp., is high; and individual parasite lineages can differ greatly in both abundance and number of host species."]