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[null,"1.","Record Nr.",null,"UNINA9911019487203321"]
[null,null,"Autore",null,"Vauquelin Georges"]
[null,null,"Titolo",null,"G protein-coupled receptors : molecular pharmacology from academic concept to pharmaceutical research / / Georges Vauquelin, Bengt von Mentzer"]
[null,null,"Pubbl/distr/stampa",null,"Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2007"]
[null,null,"ISBN",null,"9786612348709"]
[{"$nulls":4},"9781282348707"]
[{"$nulls":4},"1282348701"]
[{"$nulls":4},"9780470516652"]
[{"$nulls":4},"0470516658"]
[{"$nulls":4},"9780470516645"]
[{"$nulls":4},"047051664X"]
[null,null,"Descrizione fisica",null,"1 online resource (266 p.)"]
[null,null,"Disciplina",null,"615/.1"]
[null,null,"Soggetti",null,"G proteins - Receptors"]
[{"$nulls":4},"Molecular pharmacology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. [235]-243) and index."]
[null,null,"Nota di contenuto",null,"Chemical messengers and the cell membrane -- Radioligand binding studies -- Functional studies -- G protein-coupled receptors -- Concluding remarks."]
[null,null,null,"Sommario/riassunto","G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly.  G Protein-coupled Receptors: Molecular Pharmacology provi"]