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[null,"1.","Record Nr.",null,"UNINA9911019400303321"]
[null,null,"Titolo",null,"Neural tube defects / / [editors, Gregory Bock and Joan Marsh]"]
[null,null,"Pubbl/distr/stampa",null,"Chichester ; ; New York, : Wiley, 1994"]
[null,null,"ISBN",null,"9786612347887"]
[{"$nulls":4},"9781282347885"]
[{"$nulls":4},"1282347888"]
[{"$nulls":4},"9780470514559"]
[{"$nulls":4},"0470514558"]
[{"$nulls":4},"9780470514566"]
[{"$nulls":4},"0470514566"]
[null,null,"Descrizione fisica",null,"1 online resource (312 p.)"]
[null,null,"Collana",null,"Ciba Foundation symposium ; ; 181"]
[null,null,"Disciplina",null,"612.6"]
[{"$nulls":4},"612.64018"]
[{"$nulls":4},"616.8"]
[null,null,"Soggetti",null,"Neural tube - Abnormalities"]
[{"$nulls":4},"Nervous system - Abnormalities"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Symposium on Neural Tube Defects held at the Ciba Foundation, London, 18-20 May 1993\"--Contents p.v."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"NEURAL TUBE DEFECTS; Contents; Participants; Introduction; Normal neurulation in amphibians; Formation and patterning of the avian neuraxis: one dozen hypotheses; Normal neurulation in mammals; Neurulation in the normal human embryo; Molecular genetics of neurulation; Pax genes and neural tube defects in the mouse; Genetic models of mammalian neural tube defects; Valproic acid-induced neural tube defects; Vitamins, folic acid and the cause and prevention of neural tube defects; Folic acid metabolism and mechanisms of neural tube defects"]
[{"$nulls":4},"Folic acid and neural tube defects: the current evidence and implications for preventionPrevention of folic acid-preventable spina bifida and anencephaly; Spina bifida: anticonvulsants and other maternal influences; General discussion; Screening for neural tube defects; Meningomyelocele: management in utero and post natum; Final discussion; Index of contributors; Subject index"]
[null,null,null,"Sommario/riassunto","Neural tube defects are the second most common cause of perinatal "]
[{"$nulls":4},"death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors--both genetic and environmental--of these major human congenital malformations. They also discuss prospects for early detection by prenatal screening and for treatment both before and after birth. The extensive coverage encompasses such topics as: formation and patterning of the avian neuraxis, neurulation in mammals and the normal human embryo, folic acid and more."]