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[null,"1.","Record Nr.",null,"UNINA9911019210403321"]
[null,null,"Titolo",null,"Clinical applications of TGF-[beta]"]
[null,null,"Pubbl/distr/stampa",null,"Chichester ; ; New York, : Wiley, 1991"]
[null,null,"ISBN",null,"9786612347702"]
[{"$nulls":4},"9781282347700"]
[{"$nulls":4},"1282347705"]
[{"$nulls":4},"9780470514061"]
[{"$nulls":4},"047051406X"]
[{"$nulls":4},"9780470514078"]
[{"$nulls":4},"0470514078"]
[null,null,"Descrizione fisica",null,"1 online resource (266 p.)"]
[null,null,"Collana",null,"Ciba Foundation symposium ; ; 157"]
[null,null,"Disciplina",null,"615/.7"]
[null,null,"Soggetti",null,"Transforming growth factors-beta - Therapeutic use"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Based on the Symposium on Clinical Applications of TGF-[beta], held at the Ciba Foundation, London, June 12-14, 1990."]
[{"$nulls":4},"Editors: Gregory R. Bock and Joan Marsh."]
[{"$nulls":4},"\"A Wiley-Interscience publication.\""]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and indexes."]
[null,null,"Nota di contenuto",null,"CLINICAL APPLICATIONS OF TGF-B; Contents; Introduction; Multiple forms of TGF-B: distinct promoters and differential expression; TGF-B receptors; Mechanisms in TGF-B action; Regulation of epithelial proliferation by TGF-B; Latent forms of TGF-B: molecular structure and mechanisms of action; General discussion I : The role of TGF-B in the nervous system; TGF-B: a possible autocrine immune regulator; TGF-B and wound healing; General discussion II : A stimulatory effect of transforming growth factors on skin tumour devdopmcnt in vivo; The effects of TGF-B on bone"]
[{"$nulls":4},"TGF-B1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cellsEffects of TGF-Bs in the liver : cell proliferation and fibrogenesis; Role of TGF-B1 in experimental glomerulonephritis; The role of TGF-B in pulmonary fibrosis; In vivo and in vitro effects of TGF-B1 on normal and neoplastic haemopoiesis; Expression of TGF-B2 in human glioblastoma : a role in resistance to immune rejection?; Index of contributors; Subject index"]
[null,null,null,"Sommario/riassunto","TGF-beta, originally identified as a transforming growth factor with "]
[{"$nulls":4},"similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in others. Features the latest information on the TGF-beta family and its receptors. Describes correlations between TGF-beta and certain cancers, including glioblastomas. Also contains reports of preliminary investigations of clinical applications for TGF-beta in many diseases, including leukemia and its use to accelerate wound hea"]