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[null,"1.","Record Nr.",null,"UNINA9911018964003321"]
[null,null,"Autore",null,"Begon Michael"]
[null,null,"Titolo",null,"Population ecology : a unified study of animals and plants / / Michael Begon, Martin Mortimer, David J. Thompson"]
[null,null,"Pubbl/distr/stampa",null,"Oxford ; ; Cambridge, Mass, : Blackwell Science, 1996"]
[null,null,"ISBN",null,"9786612371738"]
[{"$nulls":4},"9781444313758"]
[{"$nulls":4},"1444313754"]
[{"$nulls":4},"9781282371736"]
[{"$nulls":4},"1282371738"]
[{"$nulls":4},"9781444313765"]
[{"$nulls":4},"1444313762"]
[{"$nulls":4},"9781405149440"]
[{"$nulls":4},"1405149442"]
[null,null,"Edizione",null,"[3rd ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (257 p.)"]
[null,null,"Disciplina",null,"574.5/248"]
[{"$nulls":4},"577.88"]
[null,null,"Soggetti",null,"Population biology"]
[{"$nulls":4},"Ecology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. 225-237) and indexes."]
[null,null,"Nota di contenuto",null,"POPULATION ECOLOGY: A Unified Study of Animals and Plants, THIRD EDITION; Contents; Preface; Part 1: SINGLE-SPECIES POPULATIONS; Chapter 1: Describing populations; 1.1 Introduction; 1.2 Population processes; 1.3 The diagrammatic life table; 1.3.1 General form; 1.3.2 The common field grasshopper, an annual species; 1.3.3 Ragwort, a biennial; 1.3.4 More complex life cycles; 1.3.5 Age and stage: the problems of describing some plant and animal populations; 1.4 Conventional life tables; 1.4.1 The cohort life table; 1.4.2 The static life table; 1.4.3 Resume; 1.5 Some generalizations"]
[{"$nulls":4},"1.6 The modular growth of organisms1.7 Buried seed banks; Chapter 2: Intraspecific competition; 2.1 The nature of intraspecific competition; 2.2 Three characteristics of intraspecific competition; 2.3 Density-dependence: a fourth characteristic; 2.4 Scramble and contest; 2.5 Actual effects of intraspecific competition; 2.5.1 Palmblad's data; 2.5.2 Competition in plants: a deeper look; 2.5.3 lndividual variability; 2.5.4 "]
[{"$nulls":4},"Self-thinning in plants; 2.5.5 Competition in Patella cochlear; 2.5.6 Competition in the fruit fly; 2.6 Negative competition; Chapter 3: Models of single-species populations"]
[{"$nulls":4},"3.1 Introduction3.2 Populations breeding at discrete intervals; 3.2.1 The basic equations; 3.2.2 Incorporation of a range of competition; 3.2.3 Models for annual plants; 3.3 Continuous breeding; 3.4 The utility of the equations; 3.4.1 Causes of population fluctuations; 3.4.2 The equations as descriptions; 3.4.3 'Cobwebbing'-a more general approach; 3.5 Incorporation of age-specific fecundity and mortality; 3.5.1 The matrix model; 3.5.2 Using the model; 3.5.3 A working example: Poa annua; Part 2: INTERSPECIFIC INTERACTIONS; Chapter4: Interspecific competition"]
[{"$nulls":4},"4.1 The nature of interspecific interactions4.2 Interspecific competition; 4.3 A field example: granivorous ants; 4.4 Competition between plant species: experimental approaches; 4.4.1 Manipulating density; 4.4.2 Manipulating resources; 4.5 The ecological niche; 4.6 The Competitive Exclusion Principle; 4.7 Competitive exclusion in the field; 4.8 Competitive release; 4.9 Coexistence: resource partitioning; 4.10 Character displacement; 4.11 Competition: its avoidance or its non-existence?; 4.12 Competition and coexistence in plants; 4.13 A logistic model of two-species competition"]
[{"$nulls":4},"4.13.1 The model's utility4.13.2 A test of the model: fruit fly competition; 4.14 Analysis of competition in plants; 4.15 Niche overlap; 4.16 Competition and heterogeneity; Chapter 5: Predation; 5.1 Introduction; 5.2 Patterns of abundance; 5.3 Coevolution, and specialization amongst predators; 5.3.1 One explanation for the degrees of specialization; 5.3.2 Food preference and predator switching; 5.4 Time and timing; 5.5 Effects on prey fitness; 5.5.1 The effects of herbivores on plant fitness; 5.6 'The effects of predation-rate on predator fitness; 5.6.1 Thresholds; 5.6.2 Food quality"]
[{"$nulls":4},"5.7 The functional response of predators to prey availability"]
[null,null,null,"Sommario/riassunto","Worldwide, Population Ecology is the leading textbook on this titled subject. Written primarily for students, it describes the present state of population ecology in terms that can be readily understood by undergraduates with little or no background in the subject. Carefully chosen experimental examples illustrate each topic, and studies of plants and animals are combined to show how fundamental principles can be derived that apply to both species. Use of complex mathematics ia avoided throughout the book, and what math is necessary is dealt with by examination of real experimental data"]
[null,"2.","Record Nr.",null,"UNINA9911019324503321"]
[null,null,"Titolo",null,"Transporters as drug carriers : structure, function, substrates / / edited by Gerhard Ecker and Peter Chiba"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim, : Wiley-VCH, c2009"]
[null,null,"ISBN",null,"9786612302466"]
[{"$nulls":4},"9781282302464"]
[{"$nulls":4},"1282302469"]
[{"$nulls":4},"9783527627424"]
[{"$nulls":4},"3527627421"]
[{"$nulls":4},"9783527627431"]
[{"$nulls":4},"352762743X"]
[null,null,"Descrizione fisica",null,"1 online resource (451 p.)"]
[null,null,"Collana",null,"Methods and principles in medicinal chemistry ; ; v. 44"]
[null,null,"Disciplina",null,"615.19"]
[null,null,"Soggetti",null,"Drug carriers (Pharmacy)"]
[{"$nulls":4},"Drugs - Physiological transport"]
[{"$nulls":4},"Drug resistance"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Transporters as Drug Carriers: Structure, Function, Substrates; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Human Transporter Families - Structure, Function, Physiology; 1 The ABC Transporters: Structural Insights into Drug Transport; 1.1 ABC Proteins - Structure and Function; 1.1.1 ABC Proteins; 1.1.2 Predicted Topology of ABC Proteins; 1.1.3 Nucleotide Binding Domains; 1.1.3.1 Conserved Motifs of NBDs; 1.1.4 Transmembrane Domains; 1.1.5 Mechanisms of Transport; 1.1.6 Energy for Translocation; 1.1.7 Coupling of ATP Hydrolysis to Transport"]
[{"$nulls":4},"1.2 Structures of ABC Transporters1.2.1 Tertiary Structure; 1.2.2 Quaternary Structure of ABC Proteins; 1.3 Multidrug Resistance and ABC Transporters; 1.3.1 P-Glycoprotein; 1.3.1.1 Historical Background; 1.3.1.2 The Role of P-gp in Drug Resistance; 1.3.1.3 Tissue Distribution and Physiological Roles; 1.3.2 Conformational Changes in the Mechanism of P-gp; 1.3.3 Comparison of Sav1866 and P-gp Structures; 1.3.4 Drug Binding Sites in P-Glycoprotein; 1.3.5 Structural Interpretation of Drug Binding; 1.3.6 Inhibitors of P-gp"]
[{"$nulls":4},"1.3.7 What Properties Are Shared by Drugs that Interact with P-Glycoprotein?1.3.8 Postscript: Further X-Ray Crystallographic Studies and a Structure for the Nucleotide-Free State of P-Glycoprotein; 1.4 Summary; References; 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters; 2.1 Nucleoside and Nucleobase Transporters; 2.1.1 Equilibrative Nucleoside Transporters; 2.1.2 Concentrative Nucleoside Transporters; 2.2 ENT and CNT Tissue Distribution, Regulation, and Physiological Roles; 2.2.1 ENT Tissue Distribution and Regulation"]
[{"$nulls":4},"2.2.2 CNT Tissue Distribution and Regulation2.2.2.1 CNTs in Absorptive Epithelia; 2.2.2.2 CNTs in Liver Parenchymal Cells; 2.2.2.3 CNTs in Immune System Cells; 2.2.2.4 CNTs in CNS; 2.2.2.5 CNTs in Other Specialized Tissues; 2.2.3 NTs as \"\"Transceptors\"\"; 2.3 Nucleoside- and Nucleobase-Derived Drug Transport into Cells; 2.3.1 Transport of Anticancer Drugs; 2.3.2 Transport of Antiviral Drugs; 2.4 Drug Transport and Responsiveness to Treatment; 2.4.1 Analysis of the Role of NTs in Sensitivity to Nucleoside Anticancer Drugs in Cultured Cell Models"]
[{"$nulls":4},"2.4.2 Studies Linking NT Function to Drug Sensitivity and Clinical Outcome in Cancer Patients2.5 Future Perspectives; References; 3 Organic Anion Transporting Polypeptides (Oatps/OATPs); 3.1 Introduction; 3.2 Nomenclature and Classification; 3.3 Tissue Distribution, Structure, and Functions; 3.4 Substrate Spectrum; 3.5 Members of the Rodent Oatp Family; 3.5.1 Oatp1a1; 3.5.2 Oatp1a3-v1/v2; 3.5.3 Oatp1a4; 3.5.4 Oatp1a5; 3.5.5 Oatp1a6; 3.5.6 Oatp1b2; 3.5.7 Oatp1c1; 3.5.8 Oatp2a1; 3.5.9 Oatp2b1; 3.5.10 Oatp3a1; 3.5.11 Oatp4a1; 3.5.12 Oatp4c1; 3.5.13 Oatp6b1/Oatp6c1; 3.5.14 PGT-2"]
[{"$nulls":4},"3.5.15 TST-1 and TST-2"]
[null,null,null,"Sommario/riassunto","This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion.As a result, this key resource lays the foundations for understanding and investi"]