{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":17,"n_cols":5,"rows_kept":17,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[5,2,5,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[9,2,9,3],[10,2,10,3],[11,2,11,3],[15,2,15,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9911004765403321"]
[null,null,"Titolo",null,"Drug design strategies : quantitative approaches / / edited by David J. Livingstone, Andrew M. Davis"]
[null,null,"Pubbl/distr/stampa",null,"Cambridge, : RSC Pub., 2012"]
[null,null,"ISBN",null,"1-62198-140-1"]
[{"$nulls":4},"1-84973-341-4"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (517 p.)"]
[null,null,"Collana",null,"RSC drug discovery series, , 2041-3203 ; ; no. 13"]
[null,null,"Disciplina",null,"615.19"]
[null,null,"Soggetti",null,"Drugs - Design - Computer simulation"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"i-iv; v-vi; vii-xviii; 1-34; 35-59; 60-87; 88-107; 108-163; 164-191; 192-219; 267-278; 220-241; 242-266; 279-311; 312-344; 345-366; 367-396; 397-439; 440-457; 458-478; 479-498"]
[null,null,null,"Sommario/riassunto","This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery process can be addressed in a quantitative fashion (ie: numerical analysis to enable robust predictions to be made). Each chapter includes a brief review of the topic showing the historical development of"]