{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":26,"n_cols":5,"rows_kept":26,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[4,2,4,3],[5,2,5,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[20,2,20,3],[21,2,21,3],[23,2,23,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910999779703321"]
[null,null,"Titolo",null,"Molecular Male Reproductive Medicine : Biology and Clinical Perspectives / / edited by C. Yan Cheng, Fei Sun"]
[null,null,"Pubbl/distr/stampa",null,"Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025"]
[null,null,"ISBN",null,"3-031-82990-5"]
[null,null,"Edizione",null,"[1st ed. 2025.]"]
[null,null,"Descrizione fisica",null,"1 online resource (VIII, 442 p. 25 illus., 24 illus. in color.)"]
[null,null,"Collana",null,"Advances in Experimental Medicine and Biology, , 2214-8019 ; ; 1469"]
[null,null,"Disciplina",null,"571.8"]
[null,null,"Soggetti",null,"Reproduction"]
[{"$nulls":4},"Physiology"]
[{"$nulls":4},"Reproductive health"]
[{"$nulls":4},"Medicine - Research"]
[{"$nulls":4},"Biology - Research"]
[{"$nulls":4},"Toxicology"]
[{"$nulls":4},"Endocrine glands"]
[{"$nulls":4},"Endocrinology"]
[{"$nulls":4},"Reproductive Physiology"]
[{"$nulls":4},"Reproductive Medicine"]
[{"$nulls":4},"Biomedical Research"]
[{"$nulls":4},"Endocrine System"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,"Nota di contenuto",null,"Current and Future Applications of Artificial Intelligence to Diagnose and Treat Male Infertility.-Immune Regulation in the Testis and Epididymis -- Innate Antiviral Defense of the Male Reproductive System -- Basal and Immune Cells of the Epididymis: An Electron Microscopy View of Their Association -- Molecular Pathways Implicated in the Differentiation and Function of Epididymal Basal cells -- Effect of Endocrine Disruptors on Testicular Function -- Unveiling the research void: exploring the reproductive effects of PFAS compounds on male health -- Computational Approaches in Spatial Transcriptomics for the Study of Mammalian Spermatogenesis -- scRNA-Seq-based transcriptome profiling and relevant bioinformatics approaches to uncover novel insights in studying human spermatogenesis -- A Comprehensive Bibliometric Analysis of Orchitis Research from 1980 to 2023 -- Non-Hormonal Contraception: Current and Emerging Targets "]
[{"$nulls":4},"-- Proteostasis as a Sentry for Sperm Quality and Male Fertility -- Sperm DNA Fragmentation and Fertility -- The Biology and Regulation of Spermatogonial Stem Cells in the Niche -- The interacting Fat1 and Dchs planar cell polarity (PCP) proteins supported by Fjx1 serve as heterodimeric intercellular bridges crucial to support spermatogenesis -- Extracellular Vesicles in the Aging Male Reproductive System: Progresses and Perspectives -- Intraflagellar transport (IFT) and sperm formation -- Microtubule-associated proteins (MAPs) are multi-functional cytoskeletal proteins in the testis that regulate spermatogenesis -- Testis is a sanctuary site for HIV-1."]
[null,null,null,"Sommario/riassunto","This book bridges the gap of basic research in male reproductive biology and its relationship to clinical studies. Bringing together a group of senior investigators with decades of experience in research and clinical investigation and keen interest in collaboration between the two areas, this book provides a balanced treatment of technical and basic research insights and cutting-edge findings, while introducing new ideas for clinical applications of this research. Section I is devoted to clinical aspects including testis biology, prostate biology, and spermatogenesis by senior investigators of male infertility treatment, particularly non-obstructive azoospermia. Section II presents the latest findings in male reproductive biology from a basic research perspective, as well as covering cutting-edge technology such as scRNA-Seq, scATAC-Seq, DNA chromatic accessibility and organization studies, genetic models, cell biology, molecular biology, and biochemistry on testis biology, and spermatogenesis. This book offers not only a cohesive summary of new findings and concepts in basic and clinical male reproductive research, it analyzes and assembles these concepts into a roadmap for the next decade of translational research, bringing lab discoveries to the bedside."]