{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":22,"n_cols":5,"rows_kept":22,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[7,2,7,3],[8,2,8,3],[9,2,9,3],[10,2,10,3],[14,2,14,3],[15,2,15,3],[19,2,19,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910971363703321"]
[null,null,"Titolo",null,"Microbial evolution and co-adaptation : a tribute to the life and scientific legacies of Joshua Lederberg : workshop summary / / rapporteurs, David A. Relman ... [et al.]"]
[null,null,"Pubbl/distr/stampa",null,"Washington, D.C., : National Academies Press, 2009"]
[null,null,"ISBN",null,"9780309177313"]
[{"$nulls":4},"0309177316"]
[{"$nulls":4},"9780309131223"]
[{"$nulls":4},"0309131227"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (329 p.)"]
[null,null,"Disciplina",null,"579/.135"]
[null,null,"Soggetti",null,"Microorganisms - Evolution"]
[{"$nulls":4},"Communicable diseases"]
[{"$nulls":4},"Evolution"]
[{"$nulls":4},"Adaptation (Biology)"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"Workshop overview -- Appendix: WO-1. Infectious history / Joshua Lederberg -- The life and legacies of Joshua Lederberg -- Reflections on the career of Joshua Lederberg / David A. Hamburg -- Joshua Lederberg remembered / Stephen S. Morse -- The life and impact of a legend-Joshua Lederberg / Adel Mahmoud -- Microbial ecology and ecosystems -- War and peace: humans and their microbiome / David A. Relman -- Deciphering the complex molecular dialogue of symbiosis: Esperanto or polyglot? / Margret McFall-Ngai -- Pathogen evolution -- Bacterial pathogenicity: an historical and experimental perspective / Stanley Falkow -- Evolution of bacterial-host interactions: virulence and the immune overresponse / Elisa Margolis and Bruce R. Levin -- Antibiotic resistance: origins and countermeasures -- Antibiotic resistance and the future of antibiotics / Julian Davies -- Microbial drug resistance: an old problem in need of new solutions / Stanley N. Cohen -- Expanding the microbial universe: metagenomics and microbial community dynamics / Jo Handelsman -- Infectious disease emergence: past, present, and future -- Emerging infections: condemned to repeat? / Stephen S. Morse -- Ecological origins of novel human pathogens / Mark Woolhouse and Eleanor Gaunt -- Genomic "]
[{"$nulls":4},"evolvability and the origin of novelty: studying the past, interpreting the present, and predicating the future / Jonathan A. Eisen -- Can we predict future trends in disease emergence? / Peter Daszak -- Appendices: A. Agenda -- B. Acronyms -- C. Glossary -- D. Forum member biographies."]
[null,null,null,"Sommario/riassunto","\"Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.\""]