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[null,"1.","Record Nr.",null,"UNINA9910966150503321"]
[null,null,"Titolo",null,"Complex mixtures : methods for in vivo toxicity testing / / Committee on Methods for the In Vivo Toxicity Testing of Complex Mixtures, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council"]
[null,null,"Pubbl/distr/stampa",null,"Washington, D.C., : National Academy Press, 1988"]
[null,null,"ISBN",null,"9786610221639"]
[{"$nulls":4},"9781280221637"]
[{"$nulls":4},"1280221631"]
[{"$nulls":4},"9780309555135"]
[{"$nulls":4},"0309555132"]
[{"$nulls":4},"9780585144603"]
[{"$nulls":4},"0585144605"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (xi, 227 pages) : illustrations"]
[null,null,"Disciplina",null,"615.9/07"]
[null,null,"Soggetti",null,"Toxicity testing - Evaluation"]
[{"$nulls":4},"Toxicology, Experimental"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographies and index."]
[null,null,"Nota di contenuto",null,"1 Front Matter; 2 Executive Summary; 3 1. Introduction; 4 2. Concepts for Analyzing Human Exposure to Complex Chemical Mixtures; 5 3. Testing Strategies and Methods; 6 4. Sampling and Chemical Characterization; 7 5. Interpretation and Modeling of Toxicity-Test Results; 8 Appendix A: Origins of Complex Mixtures; 9 Appendix B: Case Studies Establishing Active Agents and/or Interactions in Complex Mixtures; 10 Appendix C: Case Studies on Strategies for Testing the Toxicity of Complex Mixtures; 11 Appendix D: Predicting the Joint Risk of a Misture in Terms of the Component Risks; 12 Appendix E: Cancer Models; 13 Appendix F: Developmental Toxicology; 14 Appendix G: Empirical Modeling of the Toxicity of Mixtures; 15 Index"]
[null,null,null,"Sommario/riassunto","Addresses the problem of identifying and classifying complex mixtures, investigating the effect of exposure, and the research problems inherent in testing their toxicity to human beings. A series of case studies is presented, including one that examines the cofactors of alcohol consumption and cigarette smoke."]