{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":33,"n_cols":5,"rows_kept":33,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[4,2,4,3],[8,2,8,3],[9,2,9,3],[10,2,10,3],[11,2,11,3],[12,2,12,3],[20,2,20,3],[21,2,21,3],[25,2,25,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910963353403321"]
[null,null,"Autore",null,"Garcia-Segura Luis Miguel"]
[null,null,"Titolo",null,"Hormones and brain plasticity / / Luis Miguel Garcia-Segura"]
[null,null,"Pubbl/distr/stampa",null,"Oxford ; ; New York, : Oxford University Press, 2009"]
[null,null,"ISBN",null,"0-19-029613-5"]
[{"$nulls":4},"0-19-971682-X"]
[{"$nulls":4},"9786612053658"]
[{"$nulls":4},"1-282-05365-5"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (xiv, 482 pages) : illustrations (some color), plates"]
[null,null,"Collana",null,"Oxford series in behavioral neuroendocrinology"]
[null,null,"Disciplina",null,"612.8"]
[null,null,"Soggetti",null,"Neuroendocrinology"]
[{"$nulls":4},"Neuroplasticity"]
[{"$nulls":4},"Hormones - physiology"]
[{"$nulls":4},"Neuronal Plasticity - physiology"]
[{"$nulls":4},"Brain - physiology"]
[{"$nulls":4},"Brain - growth & development"]
[{"$nulls":4},"Aging - physiology"]
[{"$nulls":4},"Neuronal Plasticity"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. 309-443) and indexes."]
[null,null,"Nota di contenuto",null,"Contents; Preface and Acknowledgments; Chapter 1 Hormones and the Mutable Brain; Introduction: Endocrine Glands, Brain Plasticity, Homeostasis, Allostasis, and Homeodynamics; The Nervous System is in a Constant State of Remodeling: Cellular Plasticity and Cellular Replacement; The Classic Concept of Brain Plasticity: Cajal's Heritage; Cellular Replacement: A New Concept; Role of Hormones on Brain Mutability: Plasticity and Metaplasticity; Chapter 2 Brain Plasticity Regulates Hormonal Homeodynamics; Introduction: Brain Plasticity Regulates the Activity of Endocrine Glands"]
[{"$nulls":4},"Neuroglial Remodeling Associated with Hormonal Secretion by Hypothalamic Magnocellular NeuronsNeuroglial Remodeling in the Neurohypophysis; Neuroglial Remodeling Associated with Parvocellular Hypothalamic Neurons; Neuroglial Remodeling in the Median Eminence; Brain Plasticity and the Control of Hormonal Homeodynamics: A Recapitulation; Chapter 3 Hormonal Influences on Brain Plasticity: I. Melatonin, Thyroid Hormones and Corticosteroids; Introduction: A "]
[{"$nulls":4},"Large Variety of Hormones Regulate Brain Plasticity; Hormones or Paracrine Factors?; Melatonin; Thyroid Hormones"]
[{"$nulls":4},"Stress, Corticosteroids, and Brain PlasticityChapter 4 Hormonal Influences on Brain Plasticity: II. Sex Hormones; Introduction: Sex Hormones and Brain Remodeling; The First Evidences; Regulation by Estradiol and Progesterone of Synaptic and Glial Remodeling in the Arcuate Nucleus; Regulation by Estradiol and Progesterone of Synaptic Remodeling in the Ventromedial Hypothalamic Nucleus; Regulation by Estradiol and Progesterone of Synaptic Remodeling in the Hippocampus; Regulation by Estradiol and Progesterone of Glial Remodeling in the Hippocampus"]
[{"$nulls":4},"Regulation by Estradiol and Progesterone of Adult NeurogenesisRole of Brain Estradiol Synthesis in the Regulation of Synaptic Plasticity and Neuronal Replacement; Androgens, Synaptic Plasticity, and Cellular Replacement in the Song System of Songbirds; Androgens and Synaptic Plasticity in Motoneurons; Androgens, Synaptic plasticity, and Cellular Replacement in the Mammalian Brain; Chapter 5 Hormonal Influences on Brain Plasticity: III. Peptide Hormones; Introduction: Peptide Hormones as Regulators of Brain Remodeling; Vasopressin and Oxytocin; Corticotropin-Releasing Hormone and Urocortins"]
[{"$nulls":4},"ProlactinGonadotropin-Releasing Hormone; Insulin; Growth Hormone/Insulin-Like Growth Factor-I; Insulin-Like Growth Factor-I and Synaptic Plasticity; Insulin-Like Growth Factor-I and Adult Neurogenesis; Interactions of Insulin-Like Growth Factor-I and Estradiol in the Regulation of Brain Plasticity; Erythropoietin; Angiotensin; Feeding Hormones: Leptin, Ghrelin and Glucagon-Like Peptide-1; Hormonal Influences on Brain Plasticity: Recapitulation of the Chapters 3, 4 and 5; Chapter 6 Life Stages, Hormones, and Brain Remodeling: Early Hormonal Influences on Brain Mutability"]
[{"$nulls":4},"Introduction: Hormonal Imprinting of the Nervous System"]
[null,null,null,"Sommario/riassunto","The nervous system has a remarkable capacity for self-reorganization, and in this first systematic analysis of the interaction between hormones and brain plasticity, Luis Miguel Garcia-Segura proposes that hormones modulate metaplasticity in the brain. He covers a wide variety of hormones, brain regions, and neuroplastic events, and also provides a new theoretical background with which to interpret the interaction of hormones and brain remodeling throughout the entire life of the organism.  Garcia-Segura argues that hormones are indispensable for adequately adapting the endogenous neuroplastic"]