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[null,"1.","Record Nr.",null,"UNINA9910962841403321"]
[null,null,"Titolo",null,"The practical bioinformatician / / editor, Limsoon Wong"]
[null,null,"Pubbl/distr/stampa",null,"River Edge, N.J. ; ; London, : World Scientific, c2004"]
[null,null,"ISBN",null,"9786611872311"]
[{"$nulls":4},"9781281872319"]
[{"$nulls":4},"1281872318"]
[{"$nulls":4},"9789812562340"]
[{"$nulls":4},"9812562346"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"xxii, 517 p. : ill. (some col.), ports"]
[null,null,"Disciplina",null,"572.86330285"]
[null,null,"Soggetti",null,"Computational biology"]
[{"$nulls":4},"Bioinformatics"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. 457-509)."]
[null,null,"Nota di contenuto",null,"Chapter 1. Molecular Biology for the Practical Bioinformatician -- Chapter 2. Strategy and Planning of Bioinformatics Experiments -- Chapter 3. DataMining Techniques for the Practical Bioinformatician -- Chapter 4. Techniques for Recognition of Translation Initiation Sites -- Chapter 5. How Neural Networks Find Promoters Using Recognition of Micro-Structural Promoter Components -- Chapter 6. Neural-StatisticalModel of TATA-Box Motifs in Eukaryotes -- Chapter 7. Tuning the Dragon Promoter Finder System for Human Promoter Recognition -- Chapter 8. RNA Secondary Structure Prediction -- Chapter 9. Protein Localization Prediction -- Chapter 10. Homology Search Methods -- Chapter 11. Analysis of Phylogeny: A Case Study on Saururaceae -- Chapter 12. Functional Annotation and Protein Families: From Theory to Practice -- Chapter 13. Discovering Protein-Protein Interactions -- Chapter 14. Techniques for Analysis of Gene Expression -- Chapter 15. Genome-Wide cDNA Oligo Probe Design and its Applications in Schizosaccharomyces Pombe -- Chapter 16. Mining New Motifs from cDNA Sequence Data -- Chapter 17. Technologies for Biological Data Integration -- Chapter 18. Construction of Biological Databases: A Case Study on the Protein Phosphatase DataBase (PPDB) -- Chapter 19. A Family Classification Approach to Functional Annotation of Proteins -- Chapter 20. Informatics for Efficient EST-Based Gene Discovery in Normalized and Subtracted cDNA Libraries."]
[null,null,null,"Sommario/riassunto","Computer scientists have increasingly been enlisted as \"bioinformaticians\" to assist molecular biologists in their research. This book is a practical introduction to bioinformatics for these computer scientists. The chapters are in-depth discussions by expert bioinformaticians on both general techniques and specific approaches to a range of selected bioinformatics problems. The book is organized into clusters of chapters on the following topics: - Overview of modern molecular biology and a broad spectrum of techniques from computer science -- data mining, machine learning, mathematical modeling, sequence alignment, data integration, workflow development, etc. - In-depth discussion of computational recognition of functional and regulatory sites in DNA sequences. - Incisive discussion of computational prediction of secondary structure of RNA sequences. - Overview of computational prediction of protein cellular localization, and selected discussions of inference of protein function. - Overview of methods for discovering protein-protein interactions. - Detailed discussion of approaches to gene expression analysis for the diagnosis of diseases, the treatment of diseases, and the understanding of gene functions. - Case studies on analysis of phylogenies, functional annotation of proteins, construction of purpose-built integrated biological databases, and development of workflows underlying the large-scale-effort gene discovery."]