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[null,"1.","Record Nr.",null,"UNINA9910346735003321"]
[null,null,"Autore",null,"Isidre Ferrer"]
[null,null,"Titolo",null,"Microglial Polarization in the Pathogenesis and Therapeutics of Neurodegenerative Diseases"]
[null,null,"Pubbl/distr/stampa",null,"Frontiers Media SA, 2018"]
[null,null,"Descrizione fisica",null,"1 online resource (327 p.)"]
[null,null,"Collana",null,"Frontiers Research Topics"]
[null,null,"Soggetti",null,"Neurosciences"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Sommario/riassunto","Microglia-mediated neuroinflammation is one of the shared prominent hallmarks among various forms of neurodegeneration. Depending on the milieu in which microglia become activated, the polarization of microglia shows to be heterogeneous with diverse functional phenotypes that range from pro-inflammatory phenotypes to immunosuppressive phenotypes. Therefore, targeting microglial polarization holds great promise for the treatment of neurodegeneration. This eBook focuses on the potential mechanisms of microglial polarization that are critically associated with a broad spectrum of neurodegenerative diseases, including Parkinson's disease (PD), Alzheimer's disease (AD), Amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), Traumatic brain injury (TBI), glaucomatous neurodegeneration and prion diseases. This topic also involves the therapeutic targeting of microglial polarization by nutritional and pharmacological modulators. Moreover, this topic describes advanced technologies employed for studying microglia. Age-related changes in microglia functions are also discussed. Overall, this eBook provides comprehensive understandings of microglial polarization in the course of neurodegeneration, linking with aging-related microglial alterations and technologies developed for microglial studies. Hopefully, it will also give comprehensive insights into various aspects of therapeutic treatment for neurodegeneration, through targeting microglial polarization."]
[null,"2.","Record Nr.",null,"UNINA9910956793203321"]
[null,null,"Autore",null,"Laura R. S (Ronald S.)"]
[null,null,"Titolo",null,"Empathetic education : an ecological perspective on educational knowledge / / Ronald S. Laura and Mathew C. Cotton"]
[null,null,"Pubbl/distr/stampa",null,"London, : Falmer, 1999"]
[null,null,"ISBN",null,"1-135-71094-5"]
[{"$nulls":4},"0-203-08632-5"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (186 p.)"]
[null,null,"Collana",null,"Knowledge, identity, and school life series ; ; 7"]
[null,null,"Disciplina",null,"333.707"]
[null,null,"Soggetti",null,"Environmental education"]
[{"$nulls":4},"Knowledge, Theory of"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographies and index."]
[null,null,"Nota di contenuto",null,"Intro -- Title -- Copyright -- Contents -- Introduction -- Chapter 1. The Price We Pay for Technology -- Chapter 2. Why Educational Knowledge Is Neither Theory Free Nor Value Free -- Chapter 3. Educational Ideology and Indoctrination -- Chapter 4. The Reductionist Ghost in the Educational Machine -- Chapter 5. Towards a Reconstruction of the Foundations of Environmental Education -- Chapter 6. Extending the Boundaries of Educational Knowledge -- Chapter 7. The Epistemic Resacrilization of Nature -- Index."]
[null,null,null,"Sommario/riassunto","This book argues that the knowledge base behind current teaching is flawed, and the resulting mind-sets and attitudes are often counterproductive to the aims of environmental education."]