{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":2,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":39,"n_cols":5,"rows_kept":39,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[5,2,5,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[9,2,9,3],[14,2,14,3],[15,2,15,3],[19,2,19,3],[20,2,20,3],[20,4,20,5],[21,2,21,3],[21,4,21,5],[22,2,22,3],[22,4,22,5],[23,2,23,3],[24,2,24,3],[28,2,28,3],[29,2,29,3],[31,2,31,3],[32,2,32,3],[33,2,33,3],[37,2,37,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910480511303321"]
[null,null,"Autore",null,"Villani Cédric <1973->"]
[null,null,"Titolo",null,"Hypocoercivity / / Cédric Villani"]
[null,null,"Pubbl/distr/stampa",null,"Providence, Rhode Island : , : American Mathematical Society, , 2009"]
[{"$nulls":4},"©2009"]
[null,null,"ISBN",null,"1-4704-0564-4"]
[null,null,"Descrizione fisica",null,"1 online resource (141 p.)"]
[null,null,"Collana",null,"Memoirs of the American Mathematical Society, , 0065-9266 ; ; Volume 202, Number 950"]
[null,null,"Disciplina",null,"515/.3533"]
[null,null,"Soggetti",null,"Differential equations, Partial - Asymptotic theory"]
[{"$nulls":4},"Differential equations, Parabolic - Asymptotic theory"]
[{"$nulls":4},"Fokker-Planck equation"]
[{"$nulls":4},"Transport theory"]
[{"$nulls":4},"Electronic books."]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","\"Volume 202, Number 950 (fourth of 5 numbers).\""]
[null,null,null,"Nota di bibliografia","Includes bibliographical references."]
[null,null,"Nota di contenuto",null,"\"\"Contents\"\"; \"\"Abstract\"\"; \"\"Introduction\"\"; \"\"Part I.   =  *  +  \"\"; \"\"1. Notation\"\"; \"\"2. Operators   =  *  +  \"\"; \"\"3. Coercivity and hypocoercivity\"\"; \"\"4. Basic theorem\"\"; \"\"5. Generalization\"\"; \"\"6. Hypocoercivity in entropic sense\"\"; \"\"7. Application: The kinetic Fokker-Planck equation\"\"; \"\"8. The method of multipliers\"\"; \"\"9. Further applications and open problems\"\"; \"\"Part II. The auxiliary operator method\"\"; \"\"10. Assumptions\"\"; \"\"11. Main theorem\"\"; \"\"12. Simplified theorem and applications\"\"; \"\"13. Discussion and open problems\"\"; \"\"Part III. Fully nonlinear equations\"\""]
[null,"2.","Record Nr.",null,"UNINA9910831050803321"]
[null,null,"Autore",null,"Machin David <1939->"]
[null,null,"Titolo",null,"Design of studies for medical research [[electronic resource] /] / David Machlin, Michael J. Campbell"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, NJ, : Wiley, c2005"]
[null,null,"ISBN",null,"1-280-27566-9"]
[{"$nulls":4},"9786610275663"]
[{"$nulls":4},"0-470-01299-4"]
[{"$nulls":4},"0-470-01298-6"]
[null,null,"Descrizione fisica",null,"1 online resource (286 p.)"]
[null,null,"Disciplina",null,"610.72"]
[{"$nulls":4},"610/.72"]
[null,null,"Soggetti",null,"Medicine - Research - Methodology"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references (p. [246]-254) and index."]
[null,null,"Nota di contenuto",null,"Design of Studies for Medical Research; Contents; Preface; Chapter 1 What is Evidence?; Chapter 2 Measurement, Forms and Questionnaires; Chapter 3 Principles of Study Size Calculation; Chapter 4 Randomisation; Chapter 5 Cross-sectional and Longitudinal Studies; Chapter 6 Surveys, Cohort and Case-Control Studies; Chapter 7 Clinical Trials - General Issues; Chapter 8 Early Clinical Trials; Chapter 9 Phase III Trials; Chapter 10 Diagnosis; Chapter 11 Prognostic Factor Studies; References; Tables; Index"]
[null,null,null,"Sommario/riassunto","The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development.  With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design.  This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples f"]