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[null,"1.","Record Nr.",null,"UNINA9910830911403321"]
[null,null,"Titolo",null,"Antibodies for infectious diseases / / edited by James E. Crowe, Jr., Diana Boraschi and Rino Rappuoli"]
[null,null,"Pubbl/distr/stampa",null,"Washington, District of Columbia : , : ASM Press, , 2015"]
[{"$nulls":4},"©2015"]
[null,null,"ISBN",null,"1-68367-340-9"]
[{"$nulls":4},"1-68367-098-1"]
[{"$nulls":4},"1-55581-741-6"]
[null,null,"Descrizione fisica",null,"1 online resource (476 p.)"]
[null,null,"Disciplina",null,"616.0798"]
[null,null,"Soggetti",null,"Immunoglobulins"]
[{"$nulls":4},"Communicable diseases - Immunological aspects"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"\"\"Cover \"\"; \"\"Half Title \"\"; \"\"Title Page \"\"; \"\"Copyright \"\"; \"\"Contents \"\"; \"\"Contr ibutors \"\"; \"\"Preface \"\"; \"\"INTRODUCTION\"\"; \"\"Chapter 1: History and Practice: Antibodies in Infectious Diseases\"\"; \"\"HISTORICAL PERSPECTIVE\"\"; \"\"INTRODUCTION TO ANTIBODIES\"\"; \"\"METHODS AND PLATFORMS FOR GENERATING ANTIBODIES\"\"; \"\"STRATEGIC CONSIDERATIONS IN DEVELOPING ANTIBODY-BASED THERAPIES FOR INFECTIOUS DISEASES\"\"; \"\"EXAMPLES OF ANTIBODIES THAT ARE OR WERE IN DEVELOPMENT FOR INFECTIOUS DISEASES\"\"; \"\"FUTURE PERSPECTIVES FOR ANTIBODY TREATMENTS IN INFECTIOUS DISEASES\"\"; \"\"ACKNOWLEDGMENT\"\"; \"\"CITATION\"\""]
[{"$nulls":4},"\"\"REFERENCES\"\"\"\"GENERAL FEATURES OF  IMMUNOGLOBULINS\"\"; \"\"Chapter 2: Functions of Antibodies\"\"; \"\"INTRODUCTION\"\"; \"\"ANTIBODY FUNCTIONS INDEPENDENT OF EFFECTOR CELLS OR EFFECTOR MOLECULES\"\"; \"\"INHIBITION OF LATER STEPS\"\"; \"\"ANTIBODY FUNCTIONS DEPENDENT ON COMPLEMENT\"\"; \"\"ANTIBODY FUNCTIONS DEPENDENT ON Fc-Fc RECEPTOR INTERACTIONS\"\"; \"\"OTHER ANTIBODY FUNCTIONS\"\"; \"\"CONCLUSIONS\"\"; \"\"ACKNOWLEDGMENTS\"\"; \"\"CITATION\"\"; \"\"REFERENCES\"\"; \"\"Chapter 3: Antibody Structure\"\"; \"\"BASICS OF ANTIBODY STRUCTURE\"\"; \"\"CDR H3: SIZE AND SUBTERFUGE\"\"; \"\"HEAVY CHAIN DOMINATION AND FRAMEWORK CONTACTS\"\""]
[{"$nulls":4},"\"\"DISULFIDES IN THE CDRs\"\"\"\"SELF-CARBOHYDRATE RECOGNITION: "]
[{"$nulls":4},"PENETRATING THE GLYCAN SHIELD\"\"; \"\"UNUSUAL INDELS\"\"; \"\"MECHANISMS OF ANTIBODY NEUTRALIZATION\"\"; \"\"SUMMARY\"\"; \"\"ACKNOWLEDGMENT\"\"; \"\"CITATION\"\"; \"\"REFERENCES\"\"; \"\"Chapter 4: The Role of Complement in Antibody Therapy for Infectious Diseases\"\"; \"\"INTRODUCTION\"\"; \"\"COMPLEMENT ACTIVATION\"\"; \"\"Ab-MEDIATED COMPLEMENT ACTIVATION\"\"; \"\"EFFECTOR RESPONSES AND THEIR ROLE IN MAb TREATMENTS\"\"; \"\"MANIPULATING Ab-MEDIATED COMPLEMENT RESPONSES\"\"; \"\"COMPLEMENT EVASIVE PROPERTIES OF PATHOGENS\"\"; \"\"CONCLUSIONS AND FUTURE PERSPECTIVE\"\""]
[{"$nulls":4},"\"\"ACKNOWLEDGMENTS\"\"\"\"CITATION\"\"; \"\"REFERENCES\"\"; \"\"Chapter 5: Immunoglobulin E and Allergy: Antibodies in Immune Inflammation and Treatment\"\"; \"\"IMMUNOLOGICAL MECHANISMS OF ALLERGIC DISEASES AND THE ROLE OF IgE ANTIBODIES\"\"; \"\"IgE ANTIBODIES IN INFECTIOUS DISEASES\"\"; \"\"ANTIBODIES IN THE TREATMENT OF ALLERGIES\"\"; \"\"THE OPPOSITE SIDE OF THE COIN: HARNESSING THE ALLERGIC RESPONSE AGAINST CANCER AND THE EMERGENCE OF ANTIBODIES OF THE IgE CLASS FOR CANCER THERAPY\"\"; \"\"CONCLUDING REMARKS AND FUTURE ROLES OF ANTIBODIES IN THERAPY\"\"; \"\"ACKNOWLEDGMENTS\"\"; \"\"CITATION\"\"; \"\"REFERENCES\"\""]
[{"$nulls":4},"\"\"ANTIBODY DISCOVERY  APPROACHES\"\"\"\"Chapter 6: Phage and Yeast Display\"\"; \"\"DISCOVERY OF THERAPEUTIC ANTIBODIES USING PHAGE DISPLAY TECHNOLOGY\"\"; \"\"DISCOVERY OF THERAPEUTIC ANTIBODIES USING YEAST DISPLAY TECHNOLOGY\"\"; \"\"CONCLUSIONS\"\"; \"\"ACKNOWLEDGMENT\"\"; \"\"CITATION\"\"; \"\"REFERENCES\"\"; \"\"Chapter 7: Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells\"\"; \"\"MANY WAYS TO MAKE HUMAN MONOCLONAL ANTIBODIES\"\"; \"\"EFFICIENT IMMORTALIZATION OF MEMORY B CELLS BY USING EBV AND CpG\"\""]
[{"$nulls":4},"\"\"LONG-TERM CULTURE OF SINGLE PLASMA CELLS AND THEIR INTERROGATION USING MULTIPLE ASSAYS\"\""]