{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":22,"n_cols":5,"rows_kept":22,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[2,4,2,5],[3,2,3,3],[4,2,4,3],[8,2,8,3],[9,2,9,3],[11,2,11,3],[15,2,15,3],[16,2,16,3],[20,2,20,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910830834403321"]
[null,null,"Autore",null,"Bégué Jean-Pierre"]
[null,null,"Titolo",null,"Bioorganic and medicinal chemistry of fluorine [[electronic resource] /] / Jean-Pierre Bégué, Danièle Bonnet-Delpon ; translated from French by Julien Legros"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, N.J., : John Wiley & Sons, c2008"]
[null,null,"ISBN",null,"1-281-38145-4"]
[{"$nulls":4},"9786611381455"]
[{"$nulls":4},"0-470-28189-8"]
[{"$nulls":4},"0-470-28187-1"]
[null,null,"Descrizione fisica",null,"1 online resource (385 p.)"]
[null,null,"Disciplina",null,"547.02"]
[{"$nulls":4},"547/.02"]
[null,null,"Soggetti",null,"Fluorine compounds - Therapeutic use"]
[{"$nulls":4},"Fluorine - Physiological effect"]
[{"$nulls":4},"Organofluorine compounds"]
[{"$nulls":4},"Bioorganic chemistry"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Translated from the French."]
[null,null,null,"Nota di bibliografia","Includes bibliographic references and index."]
[null,null,"Nota di contenuto",null,"General remarks on structural, physical, and chemical properties of fluorinated compounds -- Overview on the preparation of fluorinated compounds -- Effects of fluorine substitution on biological properties -- Fluorinated analogues of natural products -- Fluorinated derivatives of ?-amino acids and proteins -- Saccharidic fluorinated derivatives -- Inhibition of enzymes by fluorinated compounds -- Fluorinated drugs."]
[null,null,null,"Sommario/riassunto","Provides a thorough overview of the role of fluorine in pharmaceutical science and development Includes chapters on fluorinated analogues of natural products, fluorinated amino acids and peptides, and derivatives of sugars Classifies marketed and in-development fluorinated pharmaceuticals according to their therapeutic classes"]