{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":25,"n_cols":5,"rows_kept":25,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[20,2,20,3],[21,2,21,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910830671203321"]
[null,null,"Titolo",null,"Hansenula polymorpha : biology and applications"]
[null,null,"Pubbl/distr/stampa",null,"[Place of publication not identified], : Wiley VCH, 2002"]
[null,null,"ISBN",null,"1-280-56085-1"]
[{"$nulls":4},"9786610560851"]
[{"$nulls":4},"3-527-60235-6"]
[null,null,"Descrizione fisica",null,"1 online resource (360 pages)"]
[null,null,"Disciplina",null,"660.65"]
[null,null,"Soggetti",null,"Methylotrophic microorganisms - Biotechnology"]
[{"$nulls":4},"Yeast fungi - Biotechnology"]
[{"$nulls":4},"Recombinant proteins"]
[{"$nulls":4},"Fungal Proteins - biosynthesis"]
[{"$nulls":4},"Fungal Proteins - therapeutic use"]
[{"$nulls":4},"Recombinant Proteins - biosynthesis"]
[{"$nulls":4},"REcombinant Proteins - therapeutic use"]
[{"$nulls":4},"Gene Expression"]
[{"$nulls":4},"Biotechnology - methods"]
[{"$nulls":4},"Bioengineering"]
[{"$nulls":4},"Mechanical Engineering"]
[{"$nulls":4},"Engineering & Applied Sciences"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Bibliographic Level Mode of Issuance: Monograph"]
[null,null,null,"Sommario/riassunto","This text is addressed to reseachers and scientists working in the field with methylotrophic yeasts, in particular hansenula polymorpha, and provides a comphrehensive overview of the present status of hensenula polymorpha research, applications and methods. Aspects of the organism ranging from systematics, genetics, methanol metabolism and peroxisomal function to its use as a technology platform for the production of recombinant proteins are covered. A detailed chapter on laboratory methods is also included."]