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[null,"1.","Record Nr.",null,"UNINA9910830374603321"]
[null,null,"Titolo",null,"Adhesives in biomedical applications / / edited by K. L. Mittal and S. Neogi"]
[null,null,"Pubbl/distr/stampa",null,"Hoboken, NJ : , : John Wiley & Sons, Inc. and Scrivener Publishing LLC, , [2023]"]
[{"$nulls":4},"©2023"]
[null,null,"ISBN",null,"1-394-20989-4"]
[{"$nulls":4},"1-394-20988-6"]
[null,null,"Edizione",null,"[1st ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (345 pages)"]
[null,null,"Collana",null,"Adhesion and Adhesives: Fundamental and Applied Aspects Series"]
[null,null,"Disciplina",null,"610/.28"]
[null,null,"Soggetti",null,"Polymers in medicine"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Part 1: General Topics -- Chapter 1 Historical Developments of Various Adhesives for Biomedical Applications -- 1.1 Origin of Adhesives -- 1.2 Prominence of Biomedical Adhesives in Wound Healing and Drug Delivery -- 1.2.1 Wound Healing -- 1.2.2 Drug Delivery -- 1.3 Generations of Bioadhesives -- 1.4 Timeline of Developments and Advances -- 1.5 Current and Future Applications -- 1.5.1 Wound Healing -- 1.5.2 Drug Delivery -- 1.5.3 Tissue Engineering -- 1.6 Summary -- References -- Chapter 2 Global Industry Development and Analysis of Adhesives for Biomedical Applications -- 2.1 Introduction -- 2.2 Research Landscape of Bioadhesives -- 2.3 Sources of Bioadhesives for Biomedical Applications -- 2.3.1 Natural Bioadhesives -- 2.3.1.1 Protein Bioadhesives -- 2.3.1.2 Carbohydrate-Based Bioadhesives -- 2.3.2 Synthetic Adhesives -- 2.3.2.1 Poly(ethylene glycol) -- 2.3.2.2 Polycyanoacrylate -- 2.3.2.3 Chondroitin Sulfate -- 2.4 Biomedical Applications of Bioadhesives -- 2.5 Latest Industrial Developments -- 2.5.1 Novel Adhesives -- 2.6 Summary -- Acknowledgment -- References -- Chapter 3 Biomedical Adhesives -- 3.1 Introduction -- 3.1.1 Definition of a Biomedical Adhesive -- 3.1.2 Proposed Mechanisms of Adhesion -- 3.1.2.1 Mechanical Interlocking -- 3.1.2.2 Electrostatic Attraction -- 3.1.2.3 Adsorption -- 3.1.2.4 Diffusion -- 3.1.2.5 Chemical Bonding -- 3.1.2.6 Weak Boundary Layers -- 3.1.3 Considerations for Development of Biomedical Adhesives -- 3.2 Types of Biomedical Adhesives and their Components "]
[{"$nulls":4},"-- 3.2.1 Soft Tissue Adhesives -- 3.2.1.1 Cyanoacrylate-Based Adhesives -- 3.2.1.2 Fibrin Glue-Based Adhesives -- 3.2.1.3 Protein-Based Adhesives -- 3.2.1.4 Polyurethane-Based Adhesives -- 3.2.1.5 Poly(ethylene glycol) (PEG)-Based Adhesives -- 3.2.1.6 Mussel-Derived Protein-Based Adhesives."]
[{"$nulls":4},"3.2.2 Hard Tissue Adhesives -- 3.2.2.1 Dental Cement -- 3.2.2.2 Bone Cements -- 3.3 Advances in Adhesives Development for Biomedical Uses -- 3.3.1 Bioglue in Surgery -- 3.3.2 Wound Dressing -- 3.4 Summary -- 3.5 Acknowledgements -- References -- Chapter 4 Bioadhesion: Fundamentals and Mechanisms -- 4.1 Introduction -- 4.2 Bioadhesion in Biological Systems -- 4.3 Bioadhesion/Mucoadhesion -- 4.3.1 Specific and Nonspecific Bioadhesion -- 4.4 The Mucosal Layer and Barriers to Drug Delivery -- 4.5 Barriers to Mucosal Drug Delivery -- 4.6 Factors Affecting Mucoadhesion -- 4.6.1 Bioadhesive Interactions -- 4.7 Mechanisms of Bioadhesion -- 4.7.1 Interface Energetics -- 4.7.2 Chemical Interactions -- 4.7.3 Mechanical Effects -- 4.8 Theories of Bioadhesion -- 4.8.1 Wetting Theory of Bioadhesion -- 4.8.2 Electrostatic Theory of Bioadhesion -- 4.8.3 Diffusion Theory of Bioadhesion -- 4.8.4 Adsorption Theory of Bioadhesion -- 4.8.5 Fracture Theory of Bioadhesion -- 4.9 Stages of Mucoadhesion -- 4.10 Modulation of Mucoadhesion -- 4.11 Molecular Biology in Bioadhesion -- 4.12 Administration of Bio- and Mucoadhesive Drug Delivery Systems -- 4.13 Prospects -- 4.14 Summary -- References -- Part 2: Specific Adhesives, Characteristics and Applications -- Chapter 5 Fibrin Glue: Sources, Characteristics and Applications -- 5.1 Introduction -- 5.2 Evolution of Fibrin Glue -- 5.3 Types of Fibrin Adhesives and their Working Mechanisms -- 5.4 Production Methods of Commercial Fibrin Adhesives -- 5.5 Comparison of Some Commercial Fibrin Adhesives -- 5.6 Recent Developments and Future Trend of Fibrin Adhesives -- 5.7 Summary -- References -- Chapter 6 Herbal Bioactives-Based Mucoadhesive Drug Delivery Systems -- 6.1 Introduction -- 6.2 Mucous Membrane -- 6.3 Theories of Adhesion -- 6.3.1 Electronic Theory -- 6.3.2 Adsorption Theory -- 6.3.3 Wetting Theory."]
[{"$nulls":4},"6.3.4 Diffusion Theory -- 6.3.5 Fracture Theory -- 6.4 Mucoadhesive Polymers -- 6.5 Mucoadhesive-Based Drug Delivery Systems (DDS): Administration Routes -- 6.5.1 Ocular Mucoadhesive DDS -- 6.5.2 Nasal DDS -- 6.5.3 Oromucosal DDS -- 6.5.4 Pulmonary Mucoadhesive DDS -- 6.5.5 Gastrointestinal Tract Mucoadhesive DDS -- 6.5.6 Vaginal Mucosal DDS -- 6.5.7 Rectal Mucoadhesive DDS -- 6.6 Clinical Studies -- 6.7 Patents on Herbal Bioactive-Based Mucoadhesive Drug Delivery Systems -- 6.8 Summary -- References -- Chapter 7 Adhesive Hydrogels -- 7.1 Introduction -- 7.1.1 Hydrogels -- 7.1.2 Conventional Adhesives in Biomedicine -- 7.1.3 Need for Adhesive Hydrogels -- 7.2 Mechanisms of Adhesion -- 7.2.1 Mechanical Interlocking -- 7.2.2 Wet Adhesion -- 7.2.3 Diffusion -- 7.2.4 van der Waals Force -- 7.2.5 Electrostatic Interaction -- 7.2.6 π-π Interaction -- 7.2.7 Hydrogen Bonding -- 7.2.8 Ionic and Covalent Bonding -- 7.3 Design Principles for Adhesive Hydrogels -- 7.4 Commonly Used Adhesive Hydrogels -- 7.4.1 Natural Polysaccharides -- 7.4.2 Poly(amino acid)s and Their Analogues -- 7.4.3 Adhesive Proteins -- 7.4.4 Synthetic Polymers -- 7.5 Prospective Applications of Adhesive Hydrogels -- 7.5.1 Biomedicine -- 7.5.2 Textiles -- 7.5.3 Food Science -- 7.5.4 Bioelectronics -- 7.5.5 Cosmetics -- 7.6 Summary -- References -- Chapter 8 Adhesives in Dermal Patches -- 8.1 Introduction -- 8.2 Types of Dermal Patches -- 8.2.1 Microreservoir Type Dermal Patches -- 8.2.2 Adhesive Dispersion Controlled Dermal Patches -- 8.2.3 Membrane Permeation Controlled Dermal Patches -- 8.2.4 Matrix Diffusion Controlled Dermal Patches -- 8.3 Evolution of "]
[{"$nulls":4},"Adhesives in Medical Applications -- 8.4 Types of Adhesives Used in Dermal Patches -- 8.4.1 PIB-Based PSAs -- 8.4.2 Silicone-Based PSAs -- 8.4.3 Acrylic PSAs -- 8.4.4 Other PSAs -- 8.5 Testing Physical Properties of PSAs."]
[{"$nulls":4},"8.5.1 Tack Test -- 8.5.2 Shear Adhesion or Creep Test -- 8.5.3 Peel Resistance Test -- 8.6 Prediction of Patch In Vivo Adhesive Performances -- 8.7 Adhesive Properties and Formulation Studies -- 8.8 Summary -- Acknowledgements -- References -- Chapter 9 Medical Adhesives from Extracted Mussel Adhesive Proteins -- 9.1 Introduction -- 9.2 The Mussel Byssus -- 9.2.1 Collagenous Thread Protein -- 9.2.2 Thread Matrix Protein -- 9.2.3 Mussel Foot Proteins (MFPs) -- 9.3 Mussel-Inspired Adhesion -- 9.3.1 History -- 9.3.2 Bioadhesives -- 9.3.2.1 Mechanisms of Biological Tissue Adhesion -- 9.3.3 Role of DOPA in Adhesion Process -- 9.3.3.1 DOPA Oxidation -- 9.3.3.2 Coacervation -- 9.3.3.3 Surface Drying -- 9.3.3.4 Catechol Modification -- 9.4 Mussel-Inspired Tissue Adhesives -- 9.4.1 Extraction of Mussel Protein -- 9.4.2 Synthesis of Catechol-Functionalized Polymers -- 9.4.2.1 Direct Functionalization -- 9.4.2.2 Polymerization of Modified Monomers -- 9.4.2.3 Methods to Synthesize Catechol Peptides -- 9.4.2.4 Recombinant Technology -- 9.4.3 Mussel-Inspired Medical Bioadhesives -- 9.4.3.1 Bioglues -- 9.4.3.2 Drug Delivery -- 9.4.3.3 Tissue Engineering -- 9.4.3.4 Cellular Engineering -- 9.5 Summary -- References -- Chapter 10 Dental Adhesives: State-of-the-Art, Current Perspectives, and Promising Applications -- 10.1 Introduction -- 10.2 Brief History of Dental Adhesive Systems -- 10.3 Classification and Composition of Adhesive Systems -- 10.3.1 Three-Step Etch-and-Rinse Conventional Adhesive System -- 10.3.2 Two-Step Etch-and-Rinse Conventional Adhesive System -- 10.3.3 Two-Step Self-Etch Adhesive System -- 10.3.4 One-Step Self-Etch Adhesive System -- 10.3.5 Universal or Multimode Adhesive System -- 10.4 Understanding the Challenges of Dental Adhesives Inside the Mouth -- 10.4.1 Host-Derived Proteolytic Enzymes -- 10.4.2 Adverse Chemical/Biochemical Interactions."]
[{"$nulls":4},"10.4.3 Mechanical Loading -- 10.5 New Approaches Targeting Longevity of Adhesive-Dentin Interfaces -- 10.6 Dental Adhesives Endowed With Antibacterial Properties -- 10.7 Summary -- 10.8 Acknowledgments -- References -- Chapter 11 Role of Adhesive-Based Systems for Diagnostic Imaging and Theranostic Applications -- 11.1 Introduction -- 11.2 Role of Adhesives in Diagnostic Imaging -- 11.2.1 X-Ray Imaging -- 11.2.2 Magnetic Resonance Imaging -- 11.2.3 Ultrasound Imaging -- 11.2.4 Endoscopy -- 11.2.5 Fluorescence Imaging -- 11.2.6 Other Applications -- 11.3 Theranostics -- 11.3.1 DOPA (3,4-dihydroxyl-L-phenylalanine) and Dopamine -- 11.3.2 Gelatin -- 11.3.3 Chitosan -- 11.3.4 Poly(lactic-co-glycolic acid) -- 11.3.5 Poly(acrylic acid) -- 11.4 Summary -- References -- Index -- EULA."]