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[null,"1.","Record Nr.",null,"UNINA9910830098803321"]
[null,null,"Titolo",null,"Multicomponent reactions [[electronic resource] /] / edited by Jieping Zhu, Hugues Bienaymé"]
[null,null,"Pubbl/distr/stampa",null,"Weinheim ; ; [Great Britain], : Wiley-VCH, c2005"]
[null,null,"ISBN",null,"1-280-51964-9"]
[{"$nulls":4},"9786610519644"]
[{"$nulls":4},"3-527-60511-8"]
[{"$nulls":4},"3-527-60424-3"]
[null,null,"Descrizione fisica",null,"1 online resource (486 p.)"]
[null,null,"Classificazione",null,"35.51"]
[null,null,"Disciplina",null,"547.2"]
[null,null,"Soggetti",null,"Catalysis"]
[{"$nulls":4},"Chemical reactions"]
[{"$nulls":4},"Chemistry, Organic"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Multicomponent Reactions; Contents; Preface; Contributors; 1 Asymmetric Isocyanide-based MCRs; 1.1 Introduction; 1.2 Racemization Issues; 1.3 Asymmetric Passerini Reactions; 1.3.1 Classical Passerini Reactions; 1.3.2 Passerini-type Reactions; 1.4 Asymmetric Intermolecular Ugi Reactions; 1.4.1 General Remarks; 1.4.2 Chiral Amines; 1.4.2.1 α-Methylbenzylamines; 1.4.2.2 Ferrocenylamines; 1.4.2.3 Glycosylamines; 1.4.2.4 Esters of α-amino Acids; 1.4.3 Chiral Isocyanides, Carboxylic Acids and Carbonyl Compounds; 1.4.4 Chiral Cyclic Imines; 1.5 Asymmetric Intramolecular Ugi Reactions"]
[{"$nulls":4},"1.5.1 With α-Amino Acids1.5.2 With Other Amino Acids; 1.5.3 With Keto Acids; 1.6 Other Asymmetric Isonitrile-based Multicomponent Reactions; 1.6.1 Tandem Ugi or Passerini Reaction/Intramolecular Diels-Alder (IMDA) Cyclizations; 1.6.2 Other Asymmetric Isonitrile-based Multicomponent Reactions; References; 2 Post-condensation Modifications of the Passerini and Ugi Reactions; 2.1 Convertible Isocyanides; 2.2 I-MCR Post-condensation Reactions in Synthesis of Open-chain Products; 2.2.1 Passerini 3CR + O-Deacylation; 2.2.2 Passerini-3CR + N-Deprotection + O N Acyl Migration"]
[{"$nulls":4},"2.2.3 Ugi-4CR + Oxidation2.2.4 Ugi-4CR + Hydrolysis; 2.2.5 Ugi-4CR in Peptide Synthesis; 2.3 I-MCR Post-condensation Reactions in the "]
[{"$nulls":4},"Synthesis of Heterocycles; 2.3.1 Three-, Four-, and Five-membered Rings and their Benzo-fused Derivatives; 2.3.1.1 Oxiranes and β-Lactams by Passerini-3CR + O- or N-alkylation; 2.3.1.2 β-Lactams and Succinimides by Ugi-4CR + C-Alkylation; 2.3.1.3 Furans, Pyrroles, and Indoles by Passerini-3CR or Ugi-4CR and Knoevenagel Condensation; 2.3.1.4 Butenolides by Passerini-3CR and the Horner-Emmons-Wadsworth Reaction"]
[{"$nulls":4},"2.3.1.5 Pyrroles and γ-Lactams by Ugi-4CR and Hydrolysis2.3.1.6 Indazolinones by Ugi-4CR with N-deprotection and Aromatic Nucleophilic Substitution; 2.3.1.7 Oxazole Derivatives and Imidazoles by Passerini-3CR or Ugi-4CR and Davidson Cyclization; 2.3.1.8 2-Imidazolines, Imidazolidin-2-ones and Benzimidazoles by Ugi-4CR with N-Deprotection and Cyclization; 2.3.1.9 Spiroimidazolones and Spirothioimidohydantoins by Ugi-4CR and Further Transformations; 2.3.2 Six-membered Rings and Their Benzo-fused Systems; 2.3.2.1 Pyridine Derivatives by Ugi-4CR and Aldol-type Condensation"]
[{"$nulls":4},"2.3.2.2 Pyridazine Derivatives by Ugi-4CR and Knoevenagel Condensation2.3.2.3 Phthalazine Derivatives by Ugi-4CR with N-Deprotection and Cyclization; 2.3.2.4 Piperazines and Pyrazin-2-ones by Ugi-4CR and Cyclization; 2.3.2.5 Ketopiperazines, 2,5-Diketopiperazines and Quinoxalines by Ugi-4CR with N-Deprotection and Intramolecular Amide Bond Formation; 2.3.2.6 2,5-Diketopiperazines and Morpholines from Bifunctional Ugi-4CR Reagents; 2.3.3 Seven-membered Rings and Their Benzo-fused Systems; 2.3.3.1 Azepines by Ugi-4CR and Ring-closing Metathesis"]
[{"$nulls":4},"2.3.3.2 1,4-Benzodiazepine-5-ones by Ugi-4CR with N-Deprotection and Aromatic Nucleophilic Substitution"]
[null,null,null,"Sommario/riassunto","In the very first book on this hot topic, the expert editors and authors present a comprehensive overview of these elegant reactions. From the contents:Organoboron compoundsFree-radical mediated multicomponent coupling reactionsApplications in drug discoveryMetal catalyzed reactionsTotal synthesis of natural productsAsymmetric isocyanide-based reactionsThe Biginelli reactionAsymmetric isocyanide-based reactionsThe Domino-Knoevenagel-Hetero-Diels-Alder Re"]